arXiv AI

Collapsibility of Performance Metrics in Clinical Predictive AI

arXiv AI
Aug 20

FairGlucose: A CGM Fairness Benchmark Reveals Subgroup Disparities Hidden in Population-Level Validation

FairGlucose is a 300‑patient CGM cohort balanced across 12 demographic strata, providing 132,480 forecasting samples and 3,945 behavioral events. Benchmarking 33 models on 2‑hour glucose forecasting revealed that population‑level validation masks significant subgroup disparities, with error ratios ranging from 0.8 to 1.4 and T1D patients experiencing 6 mg/dL higher error than T2D. The study shows that these gaps persist across all models, align with clinically hard cases, and vary with input‑length sensitivity, underscoring the need for subgroup‑disaggregated reporting in digital health AI.

By Junjie Luo, Xuzhe Zhi, Rui Han, Abhimanyu Kumbara, Anand K. Iyer, Mansur E. Shomali, Ritu Agarwal, Guodong Gordon Gao
arXiv Machine Learning
Aug 27

FRAME: separating sampling variation from representational cause in medical imaging fairness

The paper introduces FRAME, a two‑step framework for auditing fairness claims in medical imaging. First, it derives a fair‑model reference distribution that captures the portion of subgroup performance differences attributable to sampling variation. Second, it tests the remaining difference using operators in representation space to assess whether demographic information or disease entanglement drives the bias. Across a large dataset of 702,206 images and 36 encoders, the reference explains a substantial median share of race and age differences, while interventions such as injecting demographic decodability or entangling disease direction have limited impact on the residual bias.

By Mahshad Lotfinia, Daniel Truhn, Andreas Maier, Soroosh Tayebi Arasteh
Google AI Blog
Mar 15, 2024

HEAL: A framework for health equity assessment of machine learning performance

Posted by Mike Schaekermann, Research Scientist, Google Research, and Ivor Horn, Chief Health Equity Officer & Director, Google Core Health equity is a major societal concern worldwide with disparities having many causes. These sources include limitations in access to healthcare, differences in clinical treatment, and even fundamental differences in the diagnostic technology.

By Google AI