arXiv Machine Learning By Mahshad Lotfinia, Daniel Truhn, Andreas Maier, Soroosh Tayebi Arasteh

FRAME: separating sampling variation from representational cause in medical imaging fairness

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The paper introduces FRAME, a two‑step framework for auditing fairness claims in medical imaging. First, it derives a fair‑model reference distribution that captures the portion of subgroup performance differences attributable to sampling variation. Second, it tests the remaining difference using operators in representation space to assess whether demographic information or disease entanglement drives the bias. Across a large dataset of 702,206 images and 36 encoders, the reference explains a substantial median share of race and age differences, while interventions such as injecting demographic decodability or entangling disease direction have limited impact on the residual bias.

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Demographically-Conditioned Synthetic Medical Images for Bias Mitigation and Bias Detection in Disease Classifiers

arXiv:2607. 14984v1 Announce Type: new Abstract: Per-subgroup fairness audits of medical image classifiers face a sample-size problem: minority subgroups in held-out test sets have so few samples that the resulting confidence intervals on per-subgroup performance are wider than the bias the audit is meant to detect.

By Mahmoud Ibrahim, Bart Elen, Chang Sun, Gokhan Ertaylan, Michel Dumontier
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Beyond Predictive Fairness: Quantifying Attribution Consistency Across Demographic Groups in Diabetic Retinopathy Screening

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