arXiv:2609.35549v2 Announce Type: replace
Abstract: Rare-disease diagnosis is a long-tail reasoning problem: phenotypes are incomplete, individual disorders are sparsely documented, and relevant evid...
By Bo Zhang, Yuchen Wang, Dongbai Li, Matthew Yu Heng Wong, Qingkai Zeng, Lijun Wang, Tien-Yin Wong, Peng Cui, Tianyu Liu
arXiv:2608.22132v1 Announce Type: cross
Abstract: Biomedical multi-hop question answering (QA) requires models to connect evidence across intermediate entities such as diseases, drugs, proteins, and...
By Zhaohan Meng, Zaiqiao Meng, Siwei Liu, Hao Xu, Ke Yuan, Iadh Ounis
EvidenceNet is a disease‑specific dataset that transforms full‑text biomedical literature into structured evidence records and graph representations, preserving study design, provenance, and quantitative support. Using an LLM‑assisted pipeline, it extracts experimentally grounded findings, normalizes entities, scores evidence quality, and links related records via typed semantic relations. The released subsets—EvidenceNet‑HCC and EvidenceNet‑CRC—contain thousands of evidence records and richly connected graphs, with high extraction and relation‑type accuracy, enabling retrieval‑augmented question answering and graph‑based tasks such as link prediction and target prioritization.
By Chang Zong, Jinyu Chen, Sicheng Lv, Si-tu Xue, Huilin Zheng, Jian Wan, Lei Zhang
The paper introduces Oph‑Guid‑RAG, a multimodal retrieval‑augmented generation system tailored for ophthalmology clinical question answering. It treats each guideline page as an independent evidence unit, retrieving page images to preserve tables, flowcharts, and layout, and employs a controllable retrieval framework with routing and filtering to reduce noise. Evaluated on HealthBench, the system outperforms GPT‑5.2 and GPT‑5.4 on hard cases, achieving significant gains in overall score and accuracy, and ablation studies confirm the importance of reranking, routing, and retrieval design.
By Shuying Chen, Sen Cui, Zhong Cao
arXiv:2607. 12310v1 Announce Type: cross Abstract: While modern question answering (QA) systems excel on clean, schema-aligned corpora, real-world knowledge is rarely so neatly packaged.
By Michael Solodko, Steven Gong, Guangwei Yu, Satya Krishna Gorti, Jesse C. Cresswell, Victor Zhong
arXiv:2603. 03322v2 Announce Type: replace-cross Abstract: Recent advancements in Large Language Model (LLM) agents have demonstrated remarkable potential in automatic knowledge discovery.
By Chaoqun Yang, Xinyu Lin, Shulin Li, Wenjie Wang, Ruihan Guo, Fuli Feng, Tat-Seng Chua
arXiv:2608.30556v1 Announce Type: new
Abstract: Path-finding over knowledge graphs has become an effective way to ground LLM reasoning on multi-hop questions. However, biomedical QA introduces two di...
By Jun Hyeong Kim, Dongki Kim, Yinhua Piao, Sung Ju Hwang
The paper introduces BRIDGE, a bilevel optimization framework that jointly trains a large language model (LLM) and a retriever for agentic reinforcement learning (ARL). It demonstrates that adapting the retriever before the policy yields better rewards, and that BRIDGE outperforms existing methods on seven open‑domain QA benchmarks and medical QA tasks, achieving significant gains in accuracy and reasoning quality.
By Quan Xiao, Mingda Liu, Gaowen Liu, Katsuki Fujisawa, Tianyi Chen
arXiv:2610.18198v1 Announce Type: new
Abstract: Knowledge graph link prediction involving unseen entities and relations requires learning transferable reasoning patterns from observed graph structure...
By Naixing Xu
arXiv:2607. 24850v2 Announce Type: replace-cross Abstract: Recent advances in large language models (LLMs) have enabled search agents to autonomously tackle complex tasks across extended search and reasoning horizons.
By Lang Mei, Xiaohan Yu, Chong Chen, Liyan Liu, Xiangnan Chen, Jinchao Ma, Chao Feng, Li Huang, Siyu Mo, Sichen Kang, Yunkun Xu, Zhihan Yang, Zhujun Xue, Jingren Zhang, Qing He, Yingdi Huang, Hao Jiang, Ziao Ma, Zewei Pan, Minhao Sun, Zhuo Tao, Jinzhao Xiao, Gangtao Xin, Huanyao Zhang, Wenjian Zhang, Jiangshan Zhang, Guojie Zhu, Fangzhou Zou, Jiaxin Mao, Wentao Zhang
The paper introduces DASE, a query engine designed to efficiently link unstructured data for multi-step reasoning tasks. DASE combines a multi-step reasoning model, a sparse materialized embedding-similarity join index (SemJI), and a co‑designed execution layer to perform multi‑attribute filtering, multi‑vector search, exact relational joins, and thresholded embedding‑similarity joins. In scientific discovery workloads, DASE outperforms traditional RDBMS, rerank, and vector‑database baselines by 6x to 46x in retrieval speed while maintaining comparable recall, and it serves as a high‑recall prefilter that reduces downstream LLM evaluation cost and improves accuracy on benchmarks such as SemBench E‑Commerce.
By Jiaming Liang, Haydn Jones, Jacob R. Gardner, Mark Yatskar, Zachary Ives
MOSAIC is a training‑free framework that adapts Graph Retrieval‑Augmented Generation (GraphRAG) to each query by converting query‑specific evidence needs into a bounded policy over seed selection, traversal, stopping, and evidence selection. It keeps the corpus graph, indexes, scoring, grounding, and answer generation shared, while an LLM analyzer tailors the exploration strategy per query. On GraphRAG‑Bench, MOSAIC improves answer correctness by over 5 points on Medical and 4 points on Novel, achieves high evidence recall and context relevancy, and reduces path and evidence evaluations compared to fixed policies.
By EunKyeong Lee, Kyeong-Jin Oh, Jinwon Kim, Hye Woo Lee, Minsang Song, Hyeongjun Jang, Junyoung Youn