arXiv AI By Shuying Chen, Sen Cui, Zhong Cao

Guideline-grounded retrieval-augmented generation for ophthalmic clinical decision support

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The paper introduces Oph‑Guid‑RAG, a multimodal retrieval‑augmented generation system tailored for ophthalmology clinical question answering. It treats each guideline page as an independent evidence unit, retrieving page images to preserve tables, flowcharts, and layout, and employs a controllable retrieval framework with routing and filtering to reduce noise. Evaluated on HealthBench, the system outperforms GPT‑5.2 and GPT‑5.4 on hard cases, achieving significant gains in overall score and accuracy, and ablation studies confirm the importance of reranking, routing, and retrieval design.

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