arXiv Machine Learning July 16, 2026 By Wenxi Liu, Michael Trimboli, Xianqi Li

AI-Augmented Adaptive Digital Twin Modeling for Brain Tumor Evolution Prediction and Treatment Scheduling

Read the original on arXiv Machine Learning →

arXiv:2607. 13877v1 Announce Type: new Abstract: Brain tumor progression exhibits spatially heterogeneous growth, patient-specific treatment response, and complex interactions with surrounding anatomy, making accurate long-term prediction challenging.

Summary generated by The Flow from the publisher's feed. The full article lives at arXiv Machine Learning.

diffusion

arXiv AI

Jun 17

Treatment Response Optimized Clinical Decision Support AI System via Digital Twin Simulation

arXiv:2606. 17405v1 Announce Type: new Abstract: Clinical decision support AI systems (CDSASs) must adapt to evolving patient conditions in real-time while adhering to strict safety constraints.

By Xinyu Qin, Anil K. Sood, Ruiheng Yu, Sara Corvigno, Elaine Stur, Lu Wang

reinforcement-learning safety

arXiv AI

Jul 7

Graph Representation Learning of Longitudinal Medical Imaging Trajectories for Treatment Response Prediction

arXiv:2607. 04912v1 Announce Type: cross Abstract: In patients with breast cancer, pathological complete response (pCR) has been established as a clinically meaningful surrogate marker for long-term outcomes.

By Johannes Kiechle, Richard Osuala, Daniel M. Lang, Stefan M. Fischer, Ivana Jan\'i\v{c}kov\'a, Karim Lekadir, Julia A. Schnabel, Jan C. Peeken

benchmarks

arXiv Machine Learning

Jun 2

MedGym:A Unified Continuous-Time Benchmark for Dynamic Medical Treatment Reinforcement Learning

arXiv:2606. 01028v1 Announce Type: new Abstract: Medical treatment recommendation poses several challenges to reinforcement learning (RL): patient physiology evolves in continuous time, measurements and interventions are performed at irregular intervals, and treatment effects vary substantially across individuals.

By Yuepeng Wang, Ken Kawano, Yongqi Zhou, Yoshihiko Fujisawa, Richard Weiss, Akifumi Wachi, Katsuki Fujisawa, Ying Chen, Mehrshad Sadria, Xin Liu, Kyoung-Sook Kim, Xiao Hu, Sebastien Gros, Xun Shen

reinforcement-learning benchmarks safety

arXiv Machine Learning

Jul 7

CLARITY: Medical World Model for Guiding Treatment Decisions by Modeling Context-Aware Disease Trajectories in Latent Space

arXiv:2512. 08029v3 Announce Type: replace Abstract: Clinical decision-making in oncology requires predicting dynamic disease evolution, a task current static AI predictors cannot perform.

By Tianxingjian Ding, Yuanhao Zou, Chen Chen, Mubarak Shah, Yu Tian

llms diffusion benchmarks

arXiv AI

Jul 13

EHR-MPC: Inference-Time Control for Sepsis Treatment with Generative Patient Digital Twins

arXiv:2607. 08793v1 Announce Type: cross Abstract: Sepsis is a leading cause of mortality, yet optimal treatment policies remain contested.

By Joshua Pickard, Wei Qi, Na Li, Ann Woolley, Lisa Cosimi, Roy Kishony, Deborah Hung

reinforcement-learning

arXiv Machine Learning

Jul 16

Multimodal Empirical Bayes Variational Autoencoders for Joint Longitudinal and Time-to-Event Modeling

arXiv:2607. 13984v1 Announce Type: cross Abstract: Longitudinal tumor measurements, dropout information, and genetic covariates provide complementary information about treatment response, but integrating these data sources within a single population modeling framework remains challenging.

By Anders Sj\"oberg, Nils Olsson, Marcus Baaz, Mats Jirstrand

multimodal

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Treatment Response Optimized Clinical Decision Support AI System via Digital Twin Simulation

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