arXiv AI

Self-Building Labs

The paper introduces the self‑building laboratory (SBL), an autonomous system that designs, configures, and operates its own laboratory setup based on a high‑level scientific goal. Unlike existing self‑driving laboratories that can only run pre‑built procedures, the SBL starts from any existing environment—whether empty or partially equipped—and builds missing capabilities such as lab layout, digital twin, robot skills, and experimental workflows. The authors demonstrate the system across multiple robots and setups, including a real‑world quantum‑dot synthesis experiment, showing that researchers can shift from manual configuration to simply specifying scientific objectives.

arXiv AI
Jul 28

Stress-testing large language model agents in a robotic chemistry laboratory

arXiv:2607. 23045v1 Announce Type: new Abstract: AI is evaluated through knowledge, reasoning and plan generation, yet scientific agency requires reliable physical action and adaptation to evidence.

By Lulu Guo, Yingkai Sun, Xiaobo Li, Luyao Ge, Ziming Wang, Haitao Zheng, Jingyu Li, Huijuan Zhang, Bingxu Chen, Daobin Liu, Yuebo Liu, Jie Li, Xiaohui Li, Linjiang Chen, Yi Luo, Jun Jiang
arXiv AI
Jul 1

A Self-Evolving Agentic System for Automated Generation and Execution of Biological Protocols

arXiv:2606. 31763v1 Announce Type: new Abstract: Autonomous wet-lab experimentation requires more than plausible protocol text: biological intent, quantitative procedures, device constraints and experimental feedback must remain aligned from protocol and SOP design to code and physical execution.

By Yankai Jiang, Weiting Tang, Haoran Sun, Zhenyu Tang, Yuejie Hou, Yingnan Han, Rubo Wang, Yueyuxiao Yang, Cheng Liang, Lilong Wang, Wenjie Lou, Xiaosong Wang, Lei Bai, Meng Yang
arXiv Machine Learning
Sep 25

LabFactory: Building and Evaluating Executable AI Labs

LabFactory is a framework that transforms a scientific brief into an executable AI lab, integrating models, knowledge resources, tools, and a controller behind a fixed interface. The builder packages the lab in a metered workspace, and a separate host evaluates the delivered artifact on held‑out inputs, ensuring the system itself is the evaluation target. Across 28 constructions in seven scientific domains, the delivered labs surpassed reference values on all 33 subtests, demonstrating that an AI agent can fully realize a scientific brief into a working, inspectable lab.

By Jinge Wu, Hongjian Zhou, Mingde Zeng, Jiayuan Zhu, Junde Wu, Jiazhen Pan, Lei Clifton, Andrew Liu, David A. Clifton
arXiv AI
Sep 16

Evaluating Verified Autonomy in Quantum Engineering

The paper introduces Quantum‑Harbor, a virtual laboratory that lets AI agents interact with quantum systems in a controlled setting, enabling verification of their actions and conclusions. Using this platform, the authors created QIQCBench, a benchmark of 49 expert‑authored tasks covering calibration, control, error correction, compilation, sensing, and networking. Testing 17 state‑of‑the‑art agentic systems on QIQCBench revealed wide variation in verified performance, highlighting a gap between demonstrated capability and reliable operation and positioning Quantum‑Harbor as a foundation for measuring progress toward verified autonomy in quantum engineering.

By Naixu Guo, Changhao Li, Siyu Cheng, Qicheng Tang, Binzhao Luo, Bikun Li, Yuxuan Du, Shihao Ru, Jiaqi Cai
arXiv AI
Jun 12

LabVLA: Grounding Vision-Language-Action Models in Scientific Laboratories

arXiv:2606. 13578v1 Announce Type: cross Abstract: Scientific laboratories increasingly rely on AI systems to reason about experiments, but the physical act of doing science remains largely outside their reach.

By Baochang Ren, Xinjie Liu, Xi Chen, Yanshuo Liu, Chenxi Li, Daqi Gao, Zeqin Su, Jintao Xing, Zirui Xue, Rui Li, Xiangyu Zhao, Shuofei Qiao, Minting Pan, Wangmeng Zuo, Lei Bai, Dongzhan Zhou, Ningyu Zhang, Huajun Chen
arXiv AI
Oct 28

Making Self-Driving Laboratories Auditable:A Unified Framework for Hybrid Actions,Measurements, and Safe Execution

The paper introduces a unified framework for self‑driving laboratories (SDLs) that integrates experimental planning, automated execution, and measurement feedback. It comprises four components: LAM, a measurement‑conditioned policy that generates robot trajectories and typed instrument API calls; OpenSDL, an execution substrate that maps operations to heterogeneous devices and records causal events; Safe‑SDL, a runtime gate that performs pre‑dispatch checks and monitors execution with signal temporal logic; and L3‑Bench, a benchmark protocol evaluating physical outcomes, timing, reproducibility, safety, and fault recovery. Together, these elements aim to address coordination and traceability challenges in SDL workflows.

By Zihan Zhang, Zeyu Wu, Xin Zhang, Mingyu Luo, Haohui Que, Tong Zhu