arXiv AI

Agentic Artificial Intelligence for Multistage Physics Experiments at a Large-Scale User Facility Particle Accelerator

arXiv:2509. 17255v2 Announce Type: replace-cross Abstract: We present the first language-model-driven agentic artificial intelligence (AI) system to autonomously execute multi-stage physics experiments on a production synchrotron light source.

arXiv AI
Jun 4

Archi: Agentic Operations at the CMS Experiment

arXiv:2606. 04755v1 Announce Type: cross Abstract: We present Archi, an open-source, end-to-end framework for scientific collaborations that combines the systematic ingestion and organization of heterogeneous data sources with the deployment of configurable, private, and extensible agents that retrieve and reason over them.

By Pietro Lugato, Luca Lavezzo, Jason Mohoney, Hasan Ozturk, Muhammad Hassan Ahmed, Juan Pablo Salas, Viphava Ohm, Krittin Phornsiricharoenphant, Gabriele Benelli, Mariarosaria D'Alfonso, Manasvita Joshi, Warren Nam, Aron Soha, Samantha Sunnarborg, Austin Swinney, Jack Tucker, Dmytro Kovalskyi, Tim Kraska, Christoph Paus
Hugging Face Trending Papers
Jun 3

Archi: Agentic Operations at the CMS Experiment

We present Archi, an open-source, end-to-end framework for scientific collaborations that combines the systematic ingestion and organization of heterogeneous data sources with the deployment of configurable, private, and extensible agents that retrieve and reason over them. An instance of Archi has been deployed for the Computing Operations team of the CMS experiment at CERN's LHC since February 2026 as a support agent for technical operators, offering retrieval and analysis capabilities by combining documentation, historical data, and live monitoring systems.

arXiv AI
Sep 7

MaxKernel: Agentic Kernel Generation for TPUs

MaxKernel is a multi‑agent system designed to generate high‑performance custom kernels for TPUs. It offers three paradigms: a Human‑in‑the‑Loop agent for collaborative design, an Autonomous agent that runs a fully automated optimization loop, and a Graph‑Based Autonomous Search for global exploration. All paradigms share specialized sub‑agents for planning, implementation, debugging, testing, and profiling, and the system consistently matches expert hand‑tuned baselines on the JaxBench suite and real‑world workloads.

By Shangkun Wang, Nina Cai, Charles Hoong, Julian Walker, Gerson Kroiz, George Vanica, Deepak Patil, Andi Gavrilescu, Hassan Sipra, Sethu Sankaran
arXiv Machine Learning
Sep 25

LabFactory: Building and Evaluating Executable AI Labs

LabFactory is a framework that transforms a scientific brief into an executable AI lab, integrating models, knowledge resources, tools, and a controller behind a fixed interface. The builder packages the lab in a metered workspace, and a separate host evaluates the delivered artifact on held‑out inputs, ensuring the system itself is the evaluation target. Across 28 constructions in seven scientific domains, the delivered labs surpassed reference values on all 33 subtests, demonstrating that an AI agent can fully realize a scientific brief into a working, inspectable lab.

By Jinge Wu, Hongjian Zhou, Mingde Zeng, Jiayuan Zhu, Junde Wu, Jiazhen Pan, Lei Clifton, Andrew Liu, David A. Clifton
arXiv AI
Aug 20

Science Done on a Machine by a Machine: AI Agents in Computational Chemistry

The Perspective reviews the rapid growth of agentic AI systems in computational chemistry, noting an increase from a handful in 2024 to about fifty by August 2026. These systems are evolving from assisting with specific tasks to autonomously designing, executing, and analyzing in‑silico experiments, even drafting manuscripts. While fully autonomous AI scientists are not yet realized and human oversight remains, the trend toward commoditized generalist agents suggests a future where specialized systems may become obsolete, prompting reflection on the field’s direction and priorities.

By Pavlo O. Dral, Hassan Nawaz, Arif Ullah
arXiv AI
Aug 6

PICopilot: An LLM-based Agentic Framework for Assisting Photonic Integrated Circuit Design via Script Generation

arXiv:2608. 01791v2 Announce Type: replace-cross Abstract: The rapid development of photonic integrated circuits (PICs) is shifting the design flow from traditional graphical user interface (GUI)-based methods to script-based methods for higher flexibility, portability, and maintainability.

By Xiaohan Jiang, Zeyu Li, Wei Zhang, Jiang Xu