arXiv:2608. 15266v1 Announce Type: cross Abstract: Functional connectome analysis examines brain-region interactions to understand and identify disorders such as autism spectrum disorder and Alzheimer's disease.
By Sijing Wu, Dongyuan Li, Miaoting Huang, Weiwei Ye, Ying Zhang, Feng Xia, Renhe Jiang
arXiv:2607. 26746v1 Announce Type: cross Abstract: Accurate identification of Alzheimers disease (AD) using resting-state functional magnetic resonance imaging (rs-fMRI) remains challenging due to the high dimensionality, noise, and complex inter-regional dependencies inherent in functional brain connectivity, which limit the effectiveness of traditional approaches based on handcrafted connectivity features or conventional machine learning models.
By Harshiddhi Pathak, Gowtham Reddy N, Mrinal Acharya, Manjunatha Mahadevappa
arXiv:2608. 07393v1 Announce Type: new Abstract: Functional Magnetic Resonance Imaging ( fMRI ) data are often pooled into collaborative multi-site consortia, as deep learning models for analyses require large datasets to generalize well.
By Deepank Girish, Yi Hao Chan, Yubin Zheng, Sukrit Gupta, Jagath C. Rajapakse
Brain-PACE is a deep Siamese MRI framework that directly estimates the pace of structural brain ageing from paired T1‑weighted MRI scans, extending the LILAC model with spatial attention, soft label distribution learning, and a Cramér distance objective. In a study of participants with mild cognitive impairment, 42.6 % showed accelerated ageing, and faster Brain‑PACE scores correlated with greater functional and cognitive impairment as well as higher regional tau burden in key brain regions. The method improves probabilistic performance, reduces prediction bias, and provides predictive uncertainty, offering a complementary longitudinal imaging phenotype sensitive to early neurodegeneration.
By Samuel Maddox (School of Computing Sciences, University of East Anglia), Jacob Newman (School of Computing Sciences, University of East Anglia), Saber Sami (Norwich Medical School, University of East Anglia), Michal Mackiewicz (School of Computing Sciences, University of East Anglia), for the Alzheimer's Disease Neuroimaging Initiative, the Australian Imaging Biomarkers, Lifestyle flagship study of ageing
arXiv:2607. 06629v1 Announce Type: new Abstract: Brain age -- the age inferred from a physiological recording -- is an emerging biomarker whose deviation from chronological age tracks neurological and psychiatric burden, and EEG is an attractive substrate for it because it is cheap, portable, and temporally rich.
By Roy Segal, Yoni Svechinsky, Tomer Fekete
arXiv:2606. 29200v1 Announce Type: new Abstract: Multi-site functional MRI (fMRI) studies are essential for robust neuropsychiatric diagnosis yet suffer severe domain shifts from scanner heterogeneity, demographics, and site-specific acquisition protocols.
By Kunyu Zhang, Tianxiang Xu
arXiv:2605.28397v2 Announce Type: replace
Abstract: Predicting which people with mild cognitive impairment will develop dementia matters for early treatment. Yet structural imaging models have relied...
By Sara Fin, Alireza Moayedikia, Uffe Kock Wiil, Alicia Troncoso
arXiv:2608. 07287v1 Announce Type: new Abstract: Headache is the most common neurological disorder in children and substantially affects quality of life.
By Guilherme S. Imai Aldeia, Clara Moon, Julie Shulman, Navil Sethna, Allison Smith, Alyssa Lebel, William G. La Cava, Scott Holmes
The study presents an explainable multimodal deep‑learning framework that combines a 3D CNN for T1‑weighted MRI with a feedforward network for harmonized clinical and demographic data to diagnose Alzheimer’s disease. Using 6,479 ADNI records and 1,703 OASIS‑3 records, the authors compare various model configurations on three‑way and pairwise diagnostic tasks, finding that performance and explanations vary by task, modality, fusion strategy, and cohort. SHAP and Integrated Gradients consistently highlight the MMSE score as the most influential tabular feature, while CAM‑based explanations differ across model setups and cohorts, indicating that explainability is not a stable property under cohort shift.
By Yusuf Brima, Marcellin Atemkeng, Lakshmana Rao Namamula, Antoine Vacavant
arXiv:2608.23936v1 Announce Type: new
Abstract: We present a dynamical-systems based model for resting-state functional magnetic resonance imaging (rs-fMRI), trained on a dataset of roughly 40K rs-fM...
By Sourav Pal, Viet Luong, Hoseok Lee, Tingting Dan, Guorong Wu, Richard Davidson, Won Hwa Kim, Vikas Singh
This review discusses how neuroimaging data can be represented as symmetric positive-definite (SPD) matrices and analyzed using the Riemannian geometry of the SPD manifold. It surveys the evolution from modality-specific SPD representations to geometric shallow and deep learning methods, emphasizing how these approaches maintain structural constraints while integrating modern AI techniques. The paper frames SPD matrix learning as a bridge between classical geometric statistics and contemporary machine learning in neuroimaging and brain‑computer interface research.
By Ce Ju, Reinmar Kobler, Antoine Collas, Motoaki Kawanabe, Cuntai Guan, Bertrand Thirion
arXiv:2607. 28681v1 Announce Type: cross Abstract: Functional magnetic resonance imaging (fMRI) is a widely used technique for studying the brain.
By Yang Zhang, Xiao Zhou, Jonathan Warrell, Avram Holmes, Xuan Zhang, Mark Gerstein