BrainNet Studio is a unified toolkit that enables the construction, analysis, and visualization of both static and dynamic brain networks. It integrates 27 algorithms—including deep learning, graph neural networks, and spatiotemporal sequence models—to support classification, biomarker identification, and the extraction of discriminative brain regions and connections. The toolkit also employs a large language model to generate researcher‑verifiable summaries of functional and structural connectivity, as well as structure‑function coupling, at individual and group levels.
By Xiwei Zeng, Shengrong Li, Yiheng Liu, Chunwei Tian, Daoqiang Zhang, Qi Zhu
arXiv:2607. 28681v1 Announce Type: cross Abstract: Functional magnetic resonance imaging (fMRI) is a widely used technique for studying the brain.
By Yang Zhang, Xiao Zhou, Jonathan Warrell, Avram Holmes, Xuan Zhang, Mark Gerstein
arXiv:2608.30418v1 Announce Type: cross
Abstract: Resting-state functional magnetic resonance imaging (rs-fMRI) functional connectivity (FC) matrices are widely used for individual-level prediction,...
By Ce Ju, Antoine Collas, Florent Bouchard, Bertrand Thirion
arXiv:2608. 07393v1 Announce Type: new Abstract: Functional Magnetic Resonance Imaging ( fMRI ) data are often pooled into collaborative multi-site consortia, as deep learning models for analyses require large datasets to generalize well.
By Deepank Girish, Yi Hao Chan, Yubin Zheng, Sukrit Gupta, Jagath C. Rajapakse
arXiv:2606. 29200v1 Announce Type: new Abstract: Multi-site functional MRI (fMRI) studies are essential for robust neuropsychiatric diagnosis yet suffer severe domain shifts from scanner heterogeneity, demographics, and site-specific acquisition protocols.
By Kunyu Zhang, Tianxiang Xu
arXiv:2608.20380v1 Announce Type: cross
Abstract: Resting-state functional magnetic resonance imaging (rs-fMRI) has enabled non-invasive mapping of functional brain interactions for computer-aided di...
By Dengyi Zhao, Zhiheng Zhou, Zihan Wang, Guiying Yan, Xingqin Qi
arXiv:2606. 03310v1 Announce Type: cross Abstract: Understanding complex interactions between brain regions is critical for early neurodegenerative disease classification such as Alzheimer's Disease (AD) and Parkinson's Disease (PD).
By Jaeyoon Sim, Soojin Hwang, Seunghun Baek, Guorong Wu, Won Hwa Kim
Functional brain networks exhibit a hierarchical organization across ROI, community, and whole-brain levels, supporting local processing, inter-community coordination, and global integration. Recent studies have demonstrated that brain community-aware modeling is beneficial for both diagnosis and biomarker identification of brain networks.
arXiv:2607. 26746v1 Announce Type: cross Abstract: Accurate identification of Alzheimers disease (AD) using resting-state functional magnetic resonance imaging (rs-fMRI) remains challenging due to the high dimensionality, noise, and complex inter-regional dependencies inherent in functional brain connectivity, which limit the effectiveness of traditional approaches based on handcrafted connectivity features or conventional machine learning models.
By Harshiddhi Pathak, Gowtham Reddy N, Mrinal Acharya, Manjunatha Mahadevappa
arXiv:2607. 07077v1 Announce Type: cross Abstract: Functional brain networks exhibit a hierarchical organization across ROI, community, and whole-brain levels, supporting local processing, inter-community coordination, and global integration.
By Yapeng Li, Bo Jiang, Ziyan Zhang, Dongdong Chen, Zhengzheng Tu
The study investigates how the geometry of resting‑state functional connectivity (FC) influences classification of brain phenotypes and cross‑site transfer, rather than focusing on model design. It finds that FC variation across subjects is concentrated in a small effective subspace, and that differences in subspace orientation across cohorts can limit transfer even when effective ranks are similar. By projecting onto leading components at the effective‑rank scale, most classification performance is retained, and the alignment of site‑specific subspaces predicts transfer performance.
"whyItMatters":"The findings highlight that aligning effective subspaces across sites is crucial for improving generalization of FC‑based classifiers, offering a geometric diagnostic for cross‑site harmonization efforts."
By Xiao Fan, Jingyuan Li, Yubo Han, Hongbin Guo, Guanya Li, Yang Hu, Wenchao Zhang, Weibin Ji, Yi Zhang
arXiv:2606. 01237v1 Announce Type: new Abstract: Mild cognitive impairment (MCI) and subjective cognitive decline (SCD) are closely associated with the early Alzheimer's disease continuum, where accurate and explainable diagnosis is important for early risk assessment and intervention.
By Xiongri Shen, Jiaqi Wang, Zhenxi Song, Yi Zhong, Leilei Zhao, Xin He, Baiying Lei, Zhiguo Zhang