arXiv Computer Vision

M2LG-DG: A Multi-modal Local-Global Domain Generalization Framework for Cross-site Major Depressive Disorder Classification

arXiv AI
Sep 21

Rhamba: Region-Aware Hybrid Attention-Mamba Framework for Self-Supervised Learning in Resting-State fMRI

Rhamba is a region‑aware pretraining framework for resting‑state fMRI that combines anatomically guided masking with hybrid Attention‑Mamba architectures. The study pretrained models on the ABIDE dataset using three masking strategies (Any, Majority, Pure) and evaluated four architectural variants, finding that the Mamba‑Attention (MA) hybrid achieved the best average AUROC on downstream schizophrenia and ADHD classification tasks. Explainable AI via Integrated Gradients highlighted that performance depends on the interaction between masking strategy and architecture rather than a single dominant configuration.

By Pankaj Pandey, Ruthwik Reddy Doodipala, Pratheek Eranki, Carolina Torres-Rojas, Manob Jyoti Saikia, Ranganatha Sitaram
arXiv Machine Learning
Sep 18

HyperAMS-Net: Adaptive Multi-Scale Spatial Hypergraph Network for Brain Disorder Classification

HyperAMS‑Net is a deep learning framework that classifies brain disorders from resting‑state fMRI or structural MRI data. It combines adaptive multi‑scale convolution, hypergraph attention, spatial‑channel attention, and adaptive feature fusion to capture complementary patterns across multiple scales and higher‑order dependencies. Evaluated on ABIDE, REST‑meta‑MDD, and ADNI datasets, it achieves state‑of‑the‑art accuracy and AUC, with ablation studies showing hypergraph attention as the most critical component.

By Proloy Kumar Mondal, Md Kamran Hussin Chowdhury, Hoi Leong Lee
arXiv Machine Learning
Jul 30

An Attention-Based Framework for Alzheimers Disease Classification Using Resting-State fMRI

arXiv:2607. 26746v1 Announce Type: cross Abstract: Accurate identification of Alzheimers disease (AD) using resting-state functional magnetic resonance imaging (rs-fMRI) remains challenging due to the high dimensionality, noise, and complex inter-regional dependencies inherent in functional brain connectivity, which limit the effectiveness of traditional approaches based on handcrafted connectivity features or conventional machine learning models.

By Harshiddhi Pathak, Gowtham Reddy N, Mrinal Acharya, Manjunatha Mahadevappa
arXiv Computer Vision
Oct 28

Systematic Morphometric Brain Autoencoding for Representation Learning in Neurodegenerative Diseases

The paper introduces SYMBA, a self‑supervised pretraining framework tailored for structural T1‑weighted brain MRI. SYMBA uses anatomically constrained masking, a multi‑scale structural similarity reconstruction loss, and a progressive curriculum to capture distributed morphometric patterns. Evaluated on nine heterogeneous cohorts and two unseen datasets, SYMBA outperforms existing neuroimaging foundation models, achieving high AUROC scores for Alzheimer’s disease classification, mild cognitive impairment conversion, and amyloid status prediction, and shows strong sample efficiency in low‑label settings.

By Nuria Balb\'as-Esteban, Albert Belenguer-Llorens, Elaheh Moradi, Jussi Tohka, Vanessa G\'omez-Verdejo, Carlos Sevilla-Salcedo