arXiv AI

DIGOM: Disentangled Interaction Graphs for Outcome prediction in Multimodal healthcare

DIGOM (Disentangled Interaction Graphs for Outcome prediction in Multimodal healthcare) is a graph-based framework that jointly models intra‑patient cross‑modal, cross‑patient same‑modal, and cross‑patient cross‑modal interactions. It learns a sparse multiplex graph with patient‑adaptive connectivity through a differentiable sampling mechanism, enabling end‑to‑end learning without a fixed neighbor count. Evaluated on MIMIC‑IV and NIH‑TB datasets across five clinical prediction tasks, DIGOM achieves the highest AUROC while using fewer connections than existing multi‑interaction approaches, and shows robustness to missing modalities and task‑specific connectivity patterns.

arXiv Machine Learning
Jul 7

OC-Distill: Ontology-aware Contrastive Learning with Cross-Modal Distillation for ICU Risk Prediction

arXiv:2604. 16878v2 Announce Type: replace Abstract: Early prediction of severe clinical deterioration and remaining length of stay can enable timely intervention and better resource allocation in high-acuity settings such as the ICU.

By Zhongyuan Liang, Junhyung Jo, Hyang-Jung Lee, Sang Kyu Kim, Irene Y. Chen
arXiv Machine Learning
Jul 20

Toward Federated Multimodal Graph Foundation Models: A Topology-Aware Multimodal Alignment Framework

arXiv:2607. 15687v1 Announce Type: new Abstract: Multimodal-attributed graphs (MAGs), whose nodes carry modalities such as images and text alongside topological structure, now pervade applications including social platforms, e-commerce, and biomedical networks, offering richer semantic signals than single-modality graphs.

By Xunkai Li, Guohao Fu, Yuming Ai, Zhengyu Wu, Hongchao Qin, Rong-Hua Li, Guoren Wang
arXiv AI
Aug 21

MKG-CARE: Case-Aware Reasoning with Multimodal Knowledge Graphs for Explainable Medical Image Diagnosis

arXiv:2605. 22547v3 Announce Type: replace-cross Abstract: Medical image diagnosis has achieved significant progress with deep learning, yet existing methods often rely on isolated visual evidence and lack the ability to effectively leverage similar cases and external knowledge.

By Yiming Xu, Yixuan Liu, Yuhang Zhang, Ling Zheng, Yihan Wang, Qi Song
arXiv Computer Vision
Sep 7

Real-World Multi-Modal and Longitudinal Lung Cancer Dataset

The paper presents a newly curated, multi-center, multi-modal, and longitudinal lung cancer dataset comprising 1,365 patients with whole-slide images, CT scans, PET scans, structured clinical data, transcriptomics, and follow-up information. The dataset features substantial, non-uniform missingness across modalities, making it ideal for evaluating robust multi-modal fusion strategies. Benchmarks on 12‑month overall survival, disease‑specific survival, and longitudinal hazard prediction demonstrate that integrating complementary modalities consistently outperforms uni-modal approaches, even under severe missing data.

By Rita Cordeiro Mendes, Maria Rita Fonseca Verdelho, Carlos Santiago, Catarina Barata
arXiv Machine Learning
Aug 27

DeMMO: Longitudinal and Cross-Disease Modelling of Digital Mobility Outcomes via Multi-Task Learning

DeMMO is an interpretable framework that models longitudinal digital mobility outcomes (DMOs) across multiple diseases and outcomes using multi-task learning. It introduces a cross-disease, cross-outcome relation-learning mechanism that learns signed relationships from longitudinal DMO coefficient matrices, allowing selective information sharing even when disease cohorts lack shared participants. Evaluated on the Mobilise‑D dataset, DeMMO outperforms nine strong baselines and identifies reliable longitudinal DMO patterns for clinical validation.

By Menghui Zhou, Zhipeng Yuan, Vitaveska Lanfranchi, Po Yang