arXiv AI
Oct 26

MEDMKG: Benchmarking Medical Knowledge Exploitation with Multimodal Knowledge Graph

MEDMKG is a new Medical Multimodal Knowledge Graph that combines visual data from MIMIC‑CXR with structured clinical knowledge from UMLS. The construction pipeline uses rule‑based tools and large language models for concept extraction and relationship modeling, and introduces a Neighbor‑aware Filtering algorithm to improve graph quality and compactness. Experiments on six datasets across three tasks show that MEDMKG enhances performance of twenty‑four baseline methods and four state‑of‑the‑art vision‑language backbones, providing a solid foundation for adaptive multimodal knowledge integration in medical AI.

By Xiaochen Wang, Yuan Zhong, Lingwei Zhang, Lisong Dai, Ting Wang, Fenglong Ma
arXiv AI
Oct 26

DIGOM: Disentangled Interaction Graphs for Outcome prediction in Multimodal healthcare

DIGOM (Disentangled Interaction Graphs for Outcome prediction in Multimodal healthcare) is a graph-based framework that jointly models intra‑patient cross‑modal, cross‑patient same‑modal, and cross‑patient cross‑modal interactions. It learns a sparse multiplex graph with patient‑adaptive connectivity through a differentiable sampling mechanism, enabling end‑to‑end learning without a fixed neighbor count. Evaluated on MIMIC‑IV and NIH‑TB datasets across five clinical prediction tasks, DIGOM achieves the highest AUROC while using fewer connections than existing multi‑interaction approaches, and shows robustness to missing modalities and task‑specific connectivity patterns.

By Hakima Laribi, Olivier Lefebvre, Dan Poenaru, Martin Valli\`eres
arXiv AI
Aug 21

MKG-CARE: Case-Aware Reasoning with Multimodal Knowledge Graphs for Explainable Medical Image Diagnosis

arXiv:2605. 22547v3 Announce Type: replace-cross Abstract: Medical image diagnosis has achieved significant progress with deep learning, yet existing methods often rely on isolated visual evidence and lack the ability to effectively leverage similar cases and external knowledge.

By Yiming Xu, Yixuan Liu, Yuhang Zhang, Ling Zheng, Yihan Wang, Qi Song
arXiv AI
Sep 7

REFINE: LLM Refinement over Budgeted Text-Attributed Graphs for Personalized Medical Concept Representation

REFINE is a framework that refines medical concept representations by creating patient‑specific temporal graphs from a global text‑attributed knowledge graph. It uses a reinforcement learning policy to allocate a personalized graph expansion budget for each observed code, then processes the resulting graph with a heterogeneous GNN and a frozen LLM that refines representations via graph‑aware soft prompts. Experiments on MIMIC‑III and MIMIC‑IV demonstrate that REFINE consistently improves various EHR prediction backbones, surpasses strong baselines, and shows robust gains across ablation studies, KG selection, and data insufficiency scenarios.

By Mohsen Nayebi Kerdabadi, Arya Hadizadeh Moghaddam, Dongjie Wang, Zijun Yao
arXiv Machine Learning
Sep 21

HERMES: Contrast-Aware Knowledge Graph Reasoning from Clinical Notes for Patient Outcome Prediction

HERMES is a graph-based framework that uses only clinical text to predict patient outcomes. It builds personalized Knowledge Graphs from clinical notes via Large‑Language‑Model‑guided extraction and Contrastive Logic Modeling, capturing temporal dynamics and treatment changes. A Graph Attention Network then synthesizes patient representations, and experiments on MIMIC‑III and MIMIC‑IV show HERMES outperforms text‑only baselines for in‑hospital mortality and 30‑day readmission prediction.

By Gia-Bach Nguyen, Hoang-Ha Nguyen, Tuan-Cuong Vuong, Trang Mai Xuan, Duy Quoc Ngo, Tien-Cuong Nguyen, Huan Vu, Thien Van Luong