arXiv Statistics ML

Sequential versus fully conditional specification for tree-based synthesis of health data

arXiv Machine Learning
Oct 22

Can synthetic data reproduce real-world findings in epidemiology? A replication study using adversarial random forests

The study evaluates whether synthetic data can replicate real epidemiological findings using a new method called adversarial random forests (ARF). Six epidemiological analyses—covering topics such as blood pressure, myocardial infarction, and diabetes—were replicated on ARF-generated synthetic data from three large cohorts, and the results consistently matched the original studies. The authors also show that ARF outperforms other tabular synthesizers in terms of utility, privacy, generalization, and computational efficiency, especially when dimensionality and variable complexity are reduced.

By Jan Kapar, Kathrin G\"unther, Lori Ann Vallis, Klaus Berger, Nadine Binder, Hermann Brenner, Stefanie Castell, Beate Fischer, Volker Harth, Bernd Holleczek, Timm Intemann, Till Ittermann, Andr\'e Karch, Thomas Keil, Lilian Krist, Berit Lange, Michael F. Leitzmann, Katharina Nimptsch, Nadia Obi, Iris Pigeot, Tobias Pischon, Tamara Schikowski, B\"orge Schmidt, Carsten Oliver Schmidt, Anja M. Sedlmair, Justine Tanoey, Harm Wienbergen, Andreas Wienke, Claudia Wigmann, Marvin N. Wright
arXiv Machine Learning
Jun 9

Synthetic but Not Realistic: The Evaluation Challenge in Generative Modelling for Structured Electronic Medical Records

arXiv:2606. 08903v1 Announce Type: new Abstract: Synthetic healthcare data are widely proposed as privacy-preserving substitutes for real patient data, yet their evaluation remains dominated by statistical similarity and predictive performance that do not reflect clinical validity.

By Nicholas I-Hsien Kuo, Blanca Gallego, Louisa Jorm
Hugging Face Trending Papers
Jun 8

Synthetic but Not Realistic: The Evaluation Challenge in Generative Modelling for Structured Electronic Medical Records

Synthetic healthcare data are widely proposed as privacy-preserving substitutes for real patient data, yet their evaluation remains dominated by statistical similarity and predictive performance that do not reflect clinical validity. We introduce a multi-dimensional evaluation framework grounded in epidemiology, assessing descriptive fidelity, clinical utility, and structural validity, corresponding to descriptive, predictive, and causal questions.

arXiv AI
Oct 9

Towards Scalable Meta-Learning of near-optimal Interpretable Models via Synthetic Model Generations

The paper presents a scalable method for meta‑learning interpretable decision trees by generating synthetic pre‑training data. It samples near‑optimal trees to create large, realistic datasets and uses the MetaTree transformer architecture to match the performance of real‑world pre‑training or costly optimal tree training. This approach cuts computational costs, offers flexible data generation, and supports efficient, scalable meta‑learning of decision trees.

By Kyaw Hpone Myint, Zhe Wu, Alexandre G. R. Day, Giri Iyengar
arXiv AI
Aug 7

Improving the Realism of Synthetic Clinical Benchmarks Under Utility Constraints

arXiv:2608. 06265v1 Announce Type: new Abstract: Synthetic clinical benchmarks for enterprise AI agents can pass existing utility checks and still remain structurally unrealistic, especially in privacy-sensitive healthcare settings where operational data are hard to access.

By Omid Bazgir, Md Nasir, Jacob Hoffman, Yang Yang, Manu Agrawal, Anusua Trivedi, Vinay Rao Dandin, Chris Gibbons, Christine Swisher
arXiv Machine Learning
Jul 7

Memisis: Orchestrating and Evaluating Synthetic Data for Tabular Health Datasets

arXiv:2605. 17758v2 Announce Type: replace Abstract: Synthetic data is widely used in healthcare to create datasets that preserve statistical properties of real data without exposing sensitive patient information.

By Nitish Nagesh, Pengbao Zhou, Atchuth Naveen Chilaparasetti, Yajat Nagaraj Kiran, Tu Nguyen, Arshia Harish Puthran, Muhjaazee Love, Aadi Sharma, Mahdi Bagheri, Ian Harris, Amir M. Rahmani
arXiv AI
Jul 23

SynPre-FL: Synthetic data-driven pretraining integrated Federated Learning training framework

arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.

By Akarsh K Nair, Muhammad Arifur Rahman, Nicholas Shopland, Andy Burton, Jun He, Yuan Shen, David Baldwin, Emma O'Dowd, Amna Burzic, Mufti Mahmud, David J. Brown