arXiv:2607. 06133v1 Announce Type: cross Abstract: Modern software systems increasingly depend on data for analysis, prediction, testing, and decision-making.
By Aurora Francesca Zanenga, Andrea Bombarda, Marsha Chechik, Saverio D'Amico, Rita De Sanctis, Alberto Zambelli, Claudio Menghi
arXiv:2607. 09404v1 Announce Type: new Abstract: Motivation: Rare disease (RD) diagnosis is frequently delayed due to the similarities in symptoms to common disease variants.
By Nicolai Dinh Khang Truong, Richard R\"ottger
arXiv:2609.23780v1 Announce Type: new
Abstract: Many real-world decisions require prioritizing high-risk cases, such as clinicians prioritizing high-risk patients before lower-risk ones. Falling rule...
By Varun Babbar, Zachery Boner, Margo Seltzer, Cynthia Rudin
arXiv:2606. 06990v1 Announce Type: new Abstract: The generation of high-fidelity synthetic Electronic Health Records (EHR) is crucial for advancing medical research while preserving patient privacy.
By Jalen Jiang, Chufan Gao, Ethan Rasmussen, Stephen Z. Xie, Jimeng Sun
The study evaluates whether synthetic data can replicate real epidemiological findings using a new method called adversarial random forests (ARF). Six epidemiological analyses—covering topics such as blood pressure, myocardial infarction, and diabetes—were replicated on ARF-generated synthetic data from three large cohorts, and the results consistently matched the original studies. The authors also show that ARF outperforms other tabular synthesizers in terms of utility, privacy, generalization, and computational efficiency, especially when dimensionality and variable complexity are reduced.
By Jan Kapar, Kathrin G\"unther, Lori Ann Vallis, Klaus Berger, Nadine Binder, Hermann Brenner, Stefanie Castell, Beate Fischer, Volker Harth, Bernd Holleczek, Timm Intemann, Till Ittermann, Andr\'e Karch, Thomas Keil, Lilian Krist, Berit Lange, Michael F. Leitzmann, Katharina Nimptsch, Nadia Obi, Iris Pigeot, Tobias Pischon, Tamara Schikowski, B\"orge Schmidt, Carsten Oliver Schmidt, Anja M. Sedlmair, Justine Tanoey, Harm Wienbergen, Andreas Wienke, Claudia Wigmann, Marvin N. Wright
arXiv:2606. 08903v1 Announce Type: new Abstract: Synthetic healthcare data are widely proposed as privacy-preserving substitutes for real patient data, yet their evaluation remains dominated by statistical similarity and predictive performance that do not reflect clinical validity.
By Nicholas I-Hsien Kuo, Blanca Gallego, Louisa Jorm
arXiv:2606. 00563v1 Announce Type: cross Abstract: Selection bias is a common and often unavoidable aspect of real-world data that challenges the generalizability of machine learning models.
By Kara Liu, Maggie Wang, Russ B. Altman
Synthetic healthcare data are widely proposed as privacy-preserving substitutes for real patient data, yet their evaluation remains dominated by statistical similarity and predictive performance that do not reflect clinical validity. We introduce a multi-dimensional evaluation framework grounded in epidemiology, assessing descriptive fidelity, clinical utility, and structural validity, corresponding to descriptive, predictive, and causal questions.
The paper presents a scalable method for meta‑learning interpretable decision trees by generating synthetic pre‑training data. It samples near‑optimal trees to create large, realistic datasets and uses the MetaTree transformer architecture to match the performance of real‑world pre‑training or costly optimal tree training. This approach cuts computational costs, offers flexible data generation, and supports efficient, scalable meta‑learning of decision trees.
By Kyaw Hpone Myint, Zhe Wu, Alexandre G. R. Day, Giri Iyengar
arXiv:2608. 06265v1 Announce Type: new Abstract: Synthetic clinical benchmarks for enterprise AI agents can pass existing utility checks and still remain structurally unrealistic, especially in privacy-sensitive healthcare settings where operational data are hard to access.
By Omid Bazgir, Md Nasir, Jacob Hoffman, Yang Yang, Manu Agrawal, Anusua Trivedi, Vinay Rao Dandin, Chris Gibbons, Christine Swisher
arXiv:2605. 17758v2 Announce Type: replace Abstract: Synthetic data is widely used in healthcare to create datasets that preserve statistical properties of real data without exposing sensitive patient information.
By Nitish Nagesh, Pengbao Zhou, Atchuth Naveen Chilaparasetti, Yajat Nagaraj Kiran, Tu Nguyen, Arshia Harish Puthran, Muhjaazee Love, Aadi Sharma, Mahdi Bagheri, Ian Harris, Amir M. Rahmani
arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.
By Akarsh K Nair, Muhammad Arifur Rahman, Nicholas Shopland, Andy Burton, Jun He, Yuan Shen, David Baldwin, Emma O'Dowd, Amna Burzic, Mufti Mahmud, David J. Brown