arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.
By Akarsh K Nair, Muhammad Arifur Rahman, Nicholas Shopland, Andy Burton, Jun He, Yuan Shen, David Baldwin, Emma O'Dowd, Amna Burzic, Mufti Mahmud, David J. Brown
arXiv:2607. 09404v1 Announce Type: new Abstract: Motivation: Rare disease (RD) diagnosis is frequently delayed due to the similarities in symptoms to common disease variants.
By Nicolai Dinh Khang Truong, Richard R\"ottger
arXiv:2608. 12805v1 Announce Type: new Abstract: Access to clinical data is essential for developing reliable healthcare machine learning systems, but direct use of electronic health records is constrained by privacy regulation, institutional review, data-use agreements, and the risk of re-identification.
By Akanta Das, Al Amin Farhad, Mrinmoy Sarkar Anto, David Rehkopf, Ayin Vala, Tanmoy Sarkar Pias
arXiv:2606. 18518v1 Announce Type: cross Abstract: The development of medical AI is constrained by limited access to high-quality clinical data due to institutional silos and strict privacy regulations such as HIPAA and GDPR.
By Arshia Ilaty, Hossein Shirazi, Manasi Chitale, Kedar Hegde, Dhanalakshmi Ramesh, Rashmi S. Manjunath, Amir Rahmani, Hajar Homayouni
arXiv:2606. 08903v1 Announce Type: new Abstract: Synthetic healthcare data are widely proposed as privacy-preserving substitutes for real patient data, yet their evaluation remains dominated by statistical similarity and predictive performance that do not reflect clinical validity.
By Nicholas I-Hsien Kuo, Blanca Gallego, Louisa Jorm
arXiv:2606. 15447v1 Announce Type: new Abstract: Electronic health record foundation models typically treat ICD diagnosis codes as flat tokens, overlooking the clinically meaningful hierarchical structure that captures disease families, subcategories, and fine-grained diagnostic detail.
By Megha Thukral, Dong Gyun Kang, Rudra Pratap Singh, Shruthi Kashinath Hiremath, Katrin H\"ansel, Thomas Pl\"otz
Synthetic healthcare data are widely proposed as privacy-preserving substitutes for real patient data, yet their evaluation remains dominated by statistical similarity and predictive performance that do not reflect clinical validity. We introduce a multi-dimensional evaluation framework grounded in epidemiology, assessing descriptive fidelity, clinical utility, and structural validity, corresponding to descriptive, predictive, and causal questions.
arXiv:2605. 17758v2 Announce Type: replace Abstract: Synthetic data is widely used in healthcare to create datasets that preserve statistical properties of real data without exposing sensitive patient information.
By Nitish Nagesh, Pengbao Zhou, Atchuth Naveen Chilaparasetti, Yajat Nagaraj Kiran, Tu Nguyen, Arshia Harish Puthran, Muhjaazee Love, Aadi Sharma, Mahdi Bagheri, Ian Harris, Amir M. Rahmani
arXiv:2608. 16273v1 Announce Type: cross Abstract: Foresight-England (Foresight-E) is the first national-scale generative foundation model of electronic health records (EHRs), developed as a research pilot strictly for COVID-19 research.
By Simon Ellershaw, Christopher Tomlinson, Zeljko Kraljevic, Spiros Denaxas, Harry Hemingway, Cathie Sudlow, Angela M. Wood, Anoop D. Shah, Richard Dobson
arXiv:2607. 19403v1 Announce Type: cross Abstract: Validating federated learning frameworks on real clinical data is an essential step between proof-of-concept demonstrations in controlled synthetic environments and deployment in real multicenter healthcare settings.
By Rodrigo Tertulino, Laercio Alencar, Ricardo Almeida
arXiv:2606. 28798v1 Announce Type: new Abstract: Objective: ICD codes are central to reimbursement, research, and population health surveillance, yet automated coding systems often struggle to integrate diagnostic signals from both clinical narratives and structured electronic health record (EHR) variables.
By Chengyuan Liu, Xinyue Zhang, Yao Li, Guanting Chen
arXiv:2505. 16941v4 Announce Type: replace-cross Abstract: Foundation models (FMs) promise to address core limitations of traditional supervised machine learning: (i) reliance on large amounts of labeled data, (ii) task specificity, and (iii) poor transportability.
By Vincent Jeanselme, Zilin Jing, Aparajita Kashyap, Chao Pang, Florent Pollet, Young Sang Choi, Xinzhuo Jiang, Yuta Kobayashi, Yanwei Li, Sara Matijevic, Karthik Natarajan, Shalmali Joshi