arXiv Machine Learning

Artemis: Anatomy-Resolved inTervention for Eliminating Multimodal NeuroImage confounderS

arXiv:2606. 18287v1 Announce Type: new Abstract: Multimodal neuroimaging, integrating functional connectivity from fMRI and structural connectivity from DTI, enables non-invasive analysis of brain networks using graph neural networks.

arXiv AI
Jul 9

Latent graph encoding of multimodal neuroimaging features with generative AI architectures

arXiv:2607. 07027v1 Announce Type: cross Abstract: While generative models enable encoding of complex neuroimaging data for feature generation and reconstruction, developing optimal architectural frameworks with appropriate encoding and latent space processes is crucial for studying structural and functional properties of the brain.

By Ishaan Batta, Meenu Ajith, Vince Calhoun
arXiv AI
Jun 2

Brain-Atlas-Guided Generative Counterfactual Attention for Explainable Cognitive Decline Diagnosis Using Multimodal Connectomes

arXiv:2606. 01237v1 Announce Type: new Abstract: Mild cognitive impairment (MCI) and subjective cognitive decline (SCD) are closely associated with the early Alzheimer's disease continuum, where accurate and explainable diagnosis is important for early risk assessment and intervention.

By Xiongri Shen, Jiaqi Wang, Zhenxi Song, Yi Zhong, Leilei Zhao, Xin He, Baiying Lei, Zhiguo Zhang
arXiv AI
3d ago

BrainNet Studio: A Unified Toolkit for Brain Network Construction, Intelligent Analysis, and Visualization

BrainNet Studio is a unified toolkit that enables the construction, analysis, and visualization of both static and dynamic brain networks. It integrates 27 algorithms—including deep learning, graph neural networks, and spatiotemporal sequence models—to support classification, biomarker identification, and the extraction of discriminative brain regions and connections. The toolkit also employs a large language model to generate researcher‑verifiable summaries of functional and structural connectivity, as well as structure‑function coupling, at individual and group levels.

By Xiwei Zeng, Shengrong Li, Yiheng Liu, Chunwei Tian, Daoqiang Zhang, Qi Zhu
arXiv AI
Jun 15

GMN4AD: Graph Matching Network for Alzheimer's Disease Diagnosis with Test-Time Domain Adaptation using Multi-centered Structure Magnetic Resonance Imaging

arXiv:2606. 13919v1 Announce Type: cross Abstract: Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that affects millions of older adults, with prevalence expected to rise significantly in the coming years.

By Chen Zhao, Huan Huang, Yixin Xie, Jiajing Huang, Weihua Zhou, Nandakumar Narayanan
arXiv Machine Learning
Sep 16

Explainable Graph-theoretical Machine Learning with Application to Alzheimer's Disease Prediction

The paper introduces Explainable Graph-theoretical Machine Learning (XGML) to build individual metabolic brain graphs from FDG-PET data and identify subgraphs predictive of multivariate Alzheimer’s disease outcomes. Using ADNI data, the best model—kernel density estimation with Hellinger distance and random forest—achieved a Pearson correlation of 0.595 across eight cognitive scores, with the highest performance on ADAS13, ADAS11, and ADASQ4. Key edges were found to be jointly but differentially predictive, indicating potential network biomarkers for cognitive decline, though external validation on OASIS3 showed weaker performance likely due to cohort differences.

By Narmina Baghirova, Duy-Thanh V\~u, Duy-Cat Can, Christelle Schneuwly Diaz, Julien Bodlet, Guillaume Blanc, Georgi Hrusanov, Bernard Ries, Oliver Y. Ch\'en
arXiv Machine Learning
Jul 23

Geometry-Guided Generative Representation for Functional Brain Graphs

arXiv:2511. 04539v2 Announce Type: replace-cross Abstract: In network neuroscience, functional brain systems are often characterized using separate yet related graph-theoretic or spectral descriptors, overlooking how these properties covary and partially overlap across individuals and conditions.

By Subati Abulikemu, Tiago Azevedo, Michail Mamalakis, John Suckling