arXiv:2606. 13919v1 Announce Type: cross Abstract: Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that affects millions of older adults, with prevalence expected to rise significantly in the coming years.
By Chen Zhao, Huan Huang, Yixin Xie, Jiajing Huang, Weihua Zhou, Nandakumar Narayanan
arXiv:2608.20380v1 Announce Type: cross
Abstract: Resting-state functional magnetic resonance imaging (rs-fMRI) has enabled non-invasive mapping of functional brain interactions for computer-aided di...
By Dengyi Zhao, Zhiheng Zhou, Zihan Wang, Guiying Yan, Xingqin Qi
arXiv:2607. 28681v1 Announce Type: cross Abstract: Functional magnetic resonance imaging (fMRI) is a widely used technique for studying the brain.
By Yang Zhang, Xiao Zhou, Jonathan Warrell, Avram Holmes, Xuan Zhang, Mark Gerstein
arXiv:2606. 03322v1 Announce Type: cross Abstract: The graphical representation of the brain offers critical insights into diagnosing and prognosing neurodegenerative disease via relationships between regions of interest (ROIs).
By Jaeyoon Sim, Minjae Lee, Guorong Wu, Won Hwa Kim
The paper introduces Explainable Graph-theoretical Machine Learning (XGML) to build individual metabolic brain graphs from FDG-PET data and identify subgraphs predictive of multivariate Alzheimer’s disease outcomes. Using ADNI data, the best model—kernel density estimation with Hellinger distance and random forest—achieved a Pearson correlation of 0.595 across eight cognitive scores, with the highest performance on ADAS13, ADAS11, and ADASQ4. Key edges were found to be jointly but differentially predictive, indicating potential network biomarkers for cognitive decline, though external validation on OASIS3 showed weaker performance likely due to cohort differences.
By Narmina Baghirova, Duy-Thanh V\~u, Duy-Cat Can, Christelle Schneuwly Diaz, Julien Bodlet, Guillaume Blanc, Georgi Hrusanov, Bernard Ries, Oliver Y. Ch\'en
arXiv:2608. 14847v1 Announce Type: new Abstract: Electroencephalogram (EEG) is a non-invasive and relatively low-cost procedure that measures brain electricity for the detection of cognitive diseases.
By An Phan, Yufei Jin, Xingquan Zhu