arXiv:2605. 23453v2 Announce Type: replace Abstract: We conducted a reproducibility-oriented re-evaluation of prior migraine classification studies, correcting for data leakage and metric bias.
arXiv:2606. 26053v1 Announce Type: cross Abstract: Synthetic data augmentation is widely used to mitigate class imbalance, but its theoretical effects on score-based classification remain poorly understood.
Synthetic data augmentation is widely used to mitigate class imbalance, but its theoretical effects on score-based classification remain poorly understood. This paper develops a framework for characterizing when synthetic minority augmentation can improve threshold-integrated and threshold-optimized metrics, including AUROC, AUPRC, best-threshold balanced accuracy, and best-threshold \(\F_1\) score.
arXiv:2509. 07605v2 Announce Type: replace-cross Abstract: Class imbalance poses a significant challenge to supervised classification, particularly in critical domains like medical diagnostics and anomaly detection where minority class instances are rare.
arXiv:2505. 13518v3 Announce Type: replace-cross Abstract: Imbalanced datasets, where one class significantly outnumbers others, remain a persistent challenge in machine learning, often biasing predictions toward the majority class and degrading classifier performance.
The paper investigates how uncertainty quantification fails in selective prediction systems when clinical data exhibit severe class imbalance, leading to systematic exclusion of minority patients. Through experiments on 56 synthetic scenarios and three neurodegenerative disease cohorts, the authors show that standard uncertainty measures become proxies for class membership rather than true ambiguity, and that combining class‑aware correction (CCR) with threshold‑aware metrics restores proper monotonicity and protects minority patients. The study proposes adopting threshold‑aligned uncertainty measures and class‑stratified evaluation to mitigate this bias and improve safety in clinical AI pipelines.
arXiv:2609.01410v1 Announce Type: cross Abstract: Generative data augmentation is widely used to mitigate class imbalance, yet its theoretical effect on downstream generalization remains poorly under...
The paper introduces a framework that distinguishes two causes of saturation in clinical prediction: a learner gap, where the model fails to use available information, and a measurement‑channel ceiling, where the recorded variables limit performance. It provides theoretical characterizations, finite‑sample diagnostics, and empirical audits across three large cohorts, showing that well‑tuned models approach the frontier while deficient learners leave large gaps. A PRISMA‑guided synthesis across 104 tasks reveals consistent channel‑level patterns, suggesting that improving the learner or the measurement channel can audit and potentially lift performance.
The paper benchmarks six long‑tail loss functions—cross‑entropy, weighted CE, class‑balanced loss, focal loss, LDAM, and logit‑adjusted softmax—across three single‑cell foundation model architectures (scGPT, scBERT, Geneformer) and three datasets (Multiple Sclerosis, Zheng68K, human Pancreas). It shows that overall accuracy masks systematic failures on rare, disease‑relevant cell types, with a consistent gap between overall accuracy, Macro‑F1, and rare‑class recall under plain cross‑entropy. The study identifies two distinct regimes of rare‑class failure, predicts reweighting efficacy by absolute training‑set size, and finds class‑balanced loss and LDAM to be the most reliable across all settings.
OCT-FedSIR is a reliability‑aware spectral framework designed for federated learning of OCT image classification in the presence of client‑dependent annotation noise and heterogeneous data distributions. It integrates class‑balanced spectral estimation, logit adjustment, complementary spectral descriptors, selective spectral relabeling, and noise‑aware federated optimization. Across 117 experimental conditions on three datasets, OCT‑FedSIR achieved a mean accuracy of 86.73%, outperforming RoFL (79.94%) and FedCorr (78.75%) and successfully identifying and correcting corrupted annotations with high precision.
arXiv:2609.23926v1 Announce Type: cross Abstract: Density-Ratio Rescoring (DRR) augments a classifier trained at the original class prior with a survey-raking dual score. Raking reweights the majorit...
arXiv:2607. 14984v1 Announce Type: new Abstract: Per-subgroup fairness audits of medical image classifiers face a sample-size problem: minority subgroups in held-out test sets have so few samples that the resulting confidence intervals on per-subgroup performance are wider than the bias the audit is meant to detect.
The study evaluates whether inflammatory biomarkers can predict cognitive impairment in older Hispanic adults using interpretable machine learning on a small clinical dataset. A leakage‑safe Bernoulli/Categorical Naive Bayes model was trained on 165 participants from the Panama Aging Research Initiative, with continuous predictors discretized via supervised chi‑square and income treated categorically. The biomarker I‑309 (CCL1) emerged as the sole reliable incremental predictor, boosting ROC‑AUC from 0.630 to 0.740 and achieving statistically significant performance across repeated cross‑validation and random partitions.