arXiv AI

Geometry-Aware Distillation for Prompt Tuning Biomedical Vision-Language Models

arXiv:2606. 04922v1 Announce Type: cross Abstract: Current prompt-based and adapter-based tuning of vision-language models (VLMs) is attractive for medical imaging, where clinical data sensitivity favors frozen backbones and annotations are limited.

arXiv AI
Sep 21

LiteMedCoT-VL: Parameter-Efficient Adaptation for Medical Visual Question Answering

LiteMedCoT-VL is a parameter‑efficient pipeline that transfers chain‑of‑thought reasoning from a 235B teacher model to a 2B student model using LoRA fine‑tuning on explanation‑enriched data. The approach enables a compact vision‑language model to perform medical visual question answering without relying on image captions, achieving 64.9% accuracy on the PMC‑VQA benchmark—an 11‑point improvement over the zero‑shot Qwen3‑VL‑4B baseline. Visual grounding analysis confirms that the model bases its predictions on image content rather than textual priors.

By Runze Ma, Shunbo Jia, Haonan Lyu, Guo Liu, Caizhi Liao
arXiv AI
Jun 11

OpenMedReason: Scientific Reasoning Supervision for Medical Vision-Language Models

arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.

By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv Computation and Language
Sep 22

Representation-guided in-context learning for medical image interpretation with multimodal large language models

arXiv:2609.24057v1 Announce Type: cross Abstract: Medical image interpretation is central to diagnosis and care, yet adapting general-purpose multimodal large language models (MLLMs) often requires r...

By Minda Zhao, Fangyu Hu, Yan Luo, Yutong Yang, Jiahui Cai, Kaichen Zhou, Manling Li, Paul Liang, Yilun Du, Lucy Q. Shen, Mengyu Wang
arXiv Computer Vision
Sep 17

Lumen: Parameter-Efficient Alignment of Pretrained Vision and Language Encoders for Zero-Shot Computational Pathology

Lumen is a pathology vision‑language model that aligns frozen unimodal foundation models (Virchow2 and BioMedBERT) using rank‑4 adapters and projection heads, training only 0.40% of the total parameters on the QUILT‑1M corpus. It achieves the highest mean chance‑corrected balanced accuracy (0.546) across nine zero‑shot patch benchmarks and demonstrates strong performance on lymph‑node metastasis detection, with AUROC scores of 0.964 internally and 0.955 externally. While it ranks third in cross‑modal retrieval, Lumen’s low‑parameter training yields competitive results at both patch and slide levels.

By Kiarash Tajbakhsh, Abdelrahman Faqieh, Michael Jopiti, Javier Garcia-Baroja, Philipp Zens, Branislav Zagrapan, Yuri Tolkach, Martin D. Berger, Aurel Perren, Bastian Dislich, Inti Zlobec, Amjad Khan
arXiv AI
Jul 28

ClinFusion: A Vision-Centric Multimodal LLM System for Holistic Medical Understanding

arXiv:2607. 24743v1 Announce Type: cross Abstract: Multimodal large language models (MLLMs) hold immense potential to revolutionize clinical practice, yet deploying them in the medical domain is fundamentally a vision-centric challenge: models must absorb knowledge from heterogeneous 2D and 3D medical images, and evaluation protocols must align with radiologists' clinical practice and provide an accurate, fine-grained and factualness-driven assessment.

By Hangjie Yuan, Yichen Qian, Zhiwei Tang, Xianzhe Xu, Lirong Wu, Sicheng Yang, Jinwang Wang, Pengju Wang, Zhitao Zeng, Yizeng Han, Yan Xing, Shengxuan Luo, Tao Feng, Qing Xie, Weigen Yao, Yi Yang, Zuozhu Liu, Jiasheng Tang, Shaocheng Wang, Jitao Wang, Jiahong Dong, Weihua Chen, Feng Xu, Fan Wang
arXiv Machine Learning
Aug 18

Comprehensive language-image pre-training for 3D medical image understanding

arXiv:2510. 15042v3 Announce Type: replace-cross Abstract: In the 3D medical image domain, vision-language pre-training is used to create vision-language encoders (VLEs) that can support radiologists by retrieving patients with similar abnormalities, predicting likelihoods of abnormality, or, with downstream adaptation, generating radiological reports.

By Tassilo Wald, Ibrahim Ethem Hamamci, Yuan Gao, Sam Bond-Taylor, Harshita Sharma, Maximilian Ilse, Cynthia Lo, Olesya Melnichenko, Anton Schwaighofer, Noel C. F. Codella, Maria Teodora Wetscherek, Klaus H. Maier-Hein, Panagiotis Korfiatis, Valentina Salvatelli, Javier Alvarez-Valle, Fernando P\'erez-Garc\'ia