arXiv Computer Vision

From Adult Renal Masses to Pediatric Wilms Tumors: Evaluating Cross-Domain Generalization of Kidney Lesion Segmentation on MRI

The study investigates whether a deep learning segmentation model trained on adult kidney MRI can generalize to pediatric Wilms tumors. Trained on single‑sequence T1 or T2 adult MRI, the model achieved a median Dice similarity coefficient (DSC) of 0.86 on an adult test set and 0.85 on a pediatric cohort, compared to 0.90 for a pediatric‑specific nnU‑Net. Although the adult‑trained model performed well, the modest performance gap indicates that pediatric training data remain valuable.

arXiv AI
Jun 9

Robust Renal Mass Segmentation on CT: A Validation Study of an AI-Based Framework

arXiv:2505. 07573v2 Announce Type: replace-cross Abstract: Renal mass segmentation has important potential to enhance the clinical workflow, especially in settings requiring quantitative assessments.

By Sarah de Boer, Hartmut H\"antze, Kiran Vaidhya Venkadesh, Myrthe A. D. Buser, Gabriel E. Humpire Mamani, Lina Xu, Lisa C. Adams, Jawed Nawabi, Keno K. Bressem, Bram van Ginneken, Mathias Prokop, Alessa Hering
arXiv Machine Learning
Sep 16

NeuroTS-Net: Multi-Class Semantic Segmentation of Pediatric Brain Tumors in Multi-Modal MRI

NeuroTS-Net is a 3‑D encoder‑decoder CNN designed for multi‑class semantic segmentation of pediatric brain tumors in multi‑modal MRI. It uses a dual‑scale raw‑detail stream, adaptive low‑resolution context selection, and detail‑preserving multipath downsampling to maintain fine intensity and boundary information while modeling broader tumor context. Trained on the BraTS 2026 pediatric dataset, it outperformed nnU‑Net and MedNeXt, achieving Dice scores of 0.938/0.937 on internal validation and 0.927/0.926 on the official challenge set.

By Darius Peteleaza, Razvan-Gabriel Dumitru, Bogdan Neamtu, Arpad Gellert, Mariana Sandu, Claudiu Matei
arXiv Computer Vision
5d ago

Segment Anything Pancreas: A Unified MRI Segmentation Model for Pancreatic Cancer Radiotherapy

The paper introduces Pancreas‑MedNeXt, a unified MRI segmentation model that simultaneously delineates the entire pancreas, its subregions, pancreatic tumors, and surrounding organs at risk (OARs) from a single MRI volume. Using a shared MedNeXt encoder‑decoder and an annotation‑aware loss, the model is trained on partially labeled data and fine‑tuned for multitask output heads. In cross‑validation on 142 PANTHER patients and external test sets, Pancreas‑MedNeXt outperforms state‑of‑the‑art methods, achieving higher Dice similarity coefficients for pancreas, tumor, and OARs. "whyItMatters":"The model’s superior performance and unified approach could streamline contouring workflows for pancreatic cancer radiotherapy, potentially improving treatment planning efficiency."

By Zach Eidex, Mojtaba Safari, Kundan Thind, Parag J. Parikh, Zhen Tian, Xiaofeng Yang
arXiv Computer Vision
Sep 4

Improving Clinical Target Volume Segmentation Accuracy using Anatomical Priors and Active Learning for the AGITG TOPGEAR Clinical Trial

The study explores how adding anatomical priors and active learning can improve the accuracy of deep learning models for segmenting the Clinical Target Volume (CTV) in gastric cancer radiotherapy. Using 100 retrospective CT scans, an nnU‑Net model trained on 10 expert‑contoured cases was enhanced with voxel‑wise anatomical prior maps and iterative active learning over four rounds. The combined approach raised the mean Dice Similarity Coefficient from 0.84 to 0.87, demonstrating that both techniques individually and together improve segmentation performance and generalizability.

By Phillip Chlap, Mark Lee, Trevor Leong, Matthew Field, Jason Dowling, Hang Min, Julie Chu, Jennifer Tan, Phillip K. Tran, Tomas Kron, Annette Haworth, Martin A. Ebert, Shalini K. Vinod, Lois Holloway
arXiv AI
Sep 10

Deep Learning-Based Segmentation of Peritoneal Cancer Index Regions from CT Imaging

arXiv:2604.27697v2 Announce Type: replace-cross Abstract: Peritoneal metastases (PM) are staged using the surgically determined Peritoneal Cancer Index (sPCI), which requires invasive laparoscopic as...

By Pieter C. Gort, Lotte J. S. Fleurkens-Ewals, Lenah D. Kampmeijer, Anna F. van Herwijnen, Marion W. Tops-Welten, Cris H. B. Claessens, Joost Nederend, Ignace H. J. T. De Hingh, Max J. Lahaye, Misha D. P. Luyer, Fons van der Sommen
arXiv AI
Sep 16

Beyond In-Distribution Metrics: A Systematic Out-of-Distribution Evaluation of Congenital Heart Disease Segmentation

The paper presents the first systematic evaluation of out‑of‑distribution generalization for congenital heart disease (CHD) segmentation, using the ImageCHD cohort as a held‑out target. It compares several segmentation architectures under different training regimes, showing that in‑distribution performance is a poor predictor of cross‑cohort robustness: nnU‑Net drops from 0.77 to 0.51 Dice, while SwinUNETR maintains higher performance at 0.67 Dice. Limited target‑domain adaptation with only 11 labeled ImageCHD cases boosts all SwinUNETR variants above 0.76 Dice, highlighting the importance of explicit cross‑dataset testing.

By Aniketh Vijesh, Shrisharanyan Vasu, Abhijit Ramesh, Clare Pomeroy-Ward, Harikrishnan Anil Maya, Sarin Xavier, Mahesh Kappanayil, Gilad Gressel
arXiv AI
Aug 19

Comprehensive framework for evaluation of deep neural networks in detection and quantification of lymphoma from PET/CT images: clinical insights, pitfalls, and observer agreement analyses

This study presents a clinically relevant framework for evaluating deep neural networks that segment lymphoma lesions in PET/CT images, addressing gaps such as out‑of‑distribution testing and comparison with expert annotators. Using 611 multi‑institutional cases, the authors assess four networks (ResUNet, SegResNet, DynUNet, SwinUNETR) with lesion‑specific metrics, detection criteria, and metabolic‑characteristic‑based thresholds, finding that models perform best on large, intense lesions. The work also demonstrates that network errors mirror those of physicians, highlighting shared challenges with small, faint lesions.

By Shadab Ahamed, Yixi Xu, Sara Kurkowska, Claire Gowdy, Joo H. O, Ingrid Bloise, Don Wilson, Patrick Martineau, Fran\c{c}ois B\'enard, Fereshteh Yousefirizi, Rahul Dodhia, Juan M. Lavista, William B. Weeks, Carlos F. Uribe, Arman Rahmim
Hugging Face Trending Papers
Jun 21

Multi-cancer detection using a computationally efficient CNN with transfer learning

This study introduces a computationally efficient convolutional neural network (CNN) architecture enhanced with transfer learning for multi-cancer detection using biomedical images. The proposed lightweight CNN model is designed to reduce computational complexity while maintaining high classification performance, making it suitable for deployment in resource-constrained environments.