arXiv AI

From Reasoning to Pixels: Grounded Medical Multimodal LLMs for VQA and Segmentation

The paper introduces MedREAL, a unified framework that aligns linguistic reasoning with spatial grounding for medical visual question answering and segmentation. MedREAL employs Seg Anchored Reasoning Pooling (SARP) to extract semantic evidence from segmentation tokens and a Reasoning-to-Visual (R2V) fusion mechanism to integrate these features into a segmentation pipeline. Using the newly created MedRAVS-13K dataset, MedREAL achieves superior performance, reporting 68.49% gIoU and 70.47% cIoU, and generates evidence masks that consistently match textual diagnoses.

arXiv AI
Jul 28

ClinFusion: A Vision-Centric Multimodal LLM System for Holistic Medical Understanding

arXiv:2607. 24743v1 Announce Type: cross Abstract: Multimodal large language models (MLLMs) hold immense potential to revolutionize clinical practice, yet deploying them in the medical domain is fundamentally a vision-centric challenge: models must absorb knowledge from heterogeneous 2D and 3D medical images, and evaluation protocols must align with radiologists' clinical practice and provide an accurate, fine-grained and factualness-driven assessment.

By Hangjie Yuan, Yichen Qian, Zhiwei Tang, Xianzhe Xu, Lirong Wu, Sicheng Yang, Jinwang Wang, Pengju Wang, Zhitao Zeng, Yizeng Han, Yan Xing, Shengxuan Luo, Tao Feng, Qing Xie, Weigen Yao, Yi Yang, Zuozhu Liu, Jiasheng Tang, Shaocheng Wang, Jitao Wang, Jiahong Dong, Weihua Chen, Feng Xu, Fan Wang
Hugging Face Trending Papers
Jul 27

ClinFusion: A Vision-Centric Multimodal LLM System for Holistic Medical Understanding

Multimodal large language models (MLLMs) hold immense potential to revolutionize clinical practice, yet deploying them in the medical domain is fundamentally a vision-centric challenge: models must absorb knowledge from heterogeneous 2D and 3D medical images, and evaluation protocols must align with radiologists' clinical practice and provide an accurate, fine-grained and factualness-driven assessment. In this paper, we introduce ClinFusion, a vision-centric MLLM designed for holistic medical understanding that systematically addresses these limitations.

arXiv AI
Jun 11

OpenMedReason: Scientific Reasoning Supervision for Medical Vision-Language Models

arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.

By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv AI
Sep 15

Concept-Grounded Reasoning with Prompt-Driven Localization for Interpretable Structured Report Generation

The paper introduces CORAL, a multimodal framework that combines spatial grounding and concept-level supervision for medical report generation. CORAL uses a prompt-driven segmentation model to localize lesions and a Concept Bottleneck module to predict multi-class clinical attributes, feeding these textual concept tokens and mask-modulated visual features into a multimodal large language model. Experiments on BUS-CoT and IU X-ray datasets show that CORAL improves diagnostic accuracy, concept consistency, and report quality compared to existing general-purpose and medical MLLMs.

By Xinyue Xu, Hongbin Lin, Juangui Xu, Hualiang Wang, Lehan Wang, Lijie Hu, Weiyang Liu, Adrian Weller, Xiaomeng Li
arXiv AI
Jun 30

IMCBench: A benchmark for multimodal LLMs in Image-grounded Medical Conversations

arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.

By Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Anchal Nema, Nivedita Wadhwa, Prashams S Jain, Rebecca Abraham, Will Kimbrough, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
arXiv Computer Vision
Sep 10

Synergistic Vision-Language Reinforcement Enables Scalable On-Demand Analysis across Diverse Clinical Tasks

arXiv:2505.03380v2 Announce Type: replace Abstract: Accurate delineation of tumors and surrounding organs-at-risk is essential for radiotherapy, surgery and treatment response assessment, yet remains...

By Haonan Wang, Jiaji Mao, Lehan Wang, Qixiang Zhang, Marawan Elbatel, Yi Qin, Huijun Hu, Baoxun Li, Wenhui Deng, Weifeng Qin, Hongrui Li, Jialin Liang, Jun Shen, Xiaomeng Li