arXiv Machine Learning

Real PMIDs, Wrong Papers: Harness Design for Biomedical Claim-Verification Agents

arXiv AI
Aug 26

Generating Biomedical Fact-Checking Reports with RL-Enhanced Agentic Search

The paper introduces BioCheck Agent, an LLM-based system that generates structured biomedical fact‑checking reports using agentic search and a reinforcement‑learning framework called EG‑GRPO. Unlike prior methods that output only supported or refuted labels, BioCheck Agent synthesizes conclusions with retrieved evidence from PubMed, employing advanced Boolean search operators. Experiments show that, compared to the base Qwen3.5‑4B model, BioCheck Agent improves label prediction accuracy on SciFact by 9.95 %, raises evidence quality by 3.7 %, and reduces hallucinations by 19.63 %.

By Jiongxiao Wang, Dingli Ma, Chaoqun Ni
arXiv AI
Jul 8

Prompt-to-Paper: Agentic AI System for Bioinformatics

arXiv:2607. 05456v1 Announce Type: new Abstract: While recent advances in large language models have enabled end-to-end automated manuscript generation, existing systems suffer from three critical deficiencies: (i) generated claims are not deterministically grounded in verifiable literature, (ii) experimental results are frequently fabricated rather than executed, and (iii) there exists no standardized, multi-dimensional framework to assess whether AI-generated manuscripts meet the quality and rigor required for real-world publication.

By Ramsha Kamran, Maheera Amjad, Zartasha Mustansar, Arsalan Shaukat, Salma Sherbaz, Muhammad U. S. Khan
arXiv AI
Sep 10

AtomCite: Verification and Correction of Supplied Page-Level Citations in Multi-Page Documents

AtomCite is an agentic framework that verifies and corrects page‑level citations in multi‑page documents by parsing answers into claims, checking each claim against the cited page image, and applying a deterministic repair policy. The authors introduce DocCite, the first benchmark for this task, built on MP‑DocVQA and DUDE, containing 928 injected instances and 1,909 verified natural errors. Across Gemini, Claude, and GPT models, AtomCite achieves about 93% verification accuracy and improves citation precision from 34% to 87‑90%, while also enhancing hallucination detection in open‑source models.

By Chen Qian, Yimeng Wang, Yu Chen, Lingfei Wu, Andreas Stathopoulos
arXiv Computation and Language
Aug 24

MedRAGChecker: Claim-Level Verification for Biomedical Retrieval-Augmented Generation

MedRAGChecker is a claim-level verification framework designed for biomedical retrieval‑augmented generation (RAG). It decomposes generated answers into atomic claims and assesses each claim’s support by combining evidence‑grounded natural language inference with biomedical knowledge‑graph consistency signals. The aggregated claim decisions provide diagnostics that distinguish retrieval and generation failures, such as faithfulness, under‑evidence, contradiction, and safety‑critical errors, and the system is distilled into compact models for scalable evaluation.

By Yuelyu Ji, Min Gu Kwak, Hang Zhang, Xizhi Wu, Chenyu Li, Yanshan Wang
arXiv AI
Oct 7

BioStudyBench: Evaluating Agents on Post-Cutoff Biomedical Studies

BioStudyBench is a new benchmark that tests AI agents on 25 long‑horizon analysis tasks derived from biomedical studies published between July and September 2026, after the models’ knowledge cutoffs. Each task gives the agent a neutral research question but no data files, requiring it to locate and download relevant public data, search literature using tools limited to pre‑cutoff records, and perform data analysis to report findings. The benchmark shows that providing data and tools improves model performance by an average of 47 percentage points, with closed‑weight models outperforming open‑weight ones (best open‑weight 81.3% vs. best closed‑weight 94.7%).

By David Li, Shaamil Karim, Christian Gensbigler