arXiv Machine Learning

AskChem: Claim-Centered Infrastructure for Chemistry Literature Synthesis

arXiv:2607. 28618v1 Announce Type: cross Abstract: Chemistry literature synthesis often requires assembling specific findings scattered across many publications, yet existing literature-search systems primarily return ranked document lists.

arXiv AI
Sep 23

ScholarStack: Layered Research Asset Orchestration and Cross-Task Reuse for Scientific Agents

arXiv:2609.23735v2 Announce Type: new Abstract: Scientific agents support a range of literature-based research tasks, such as retrieval, question answering, evidence-grounded generation, and claim as...

By ScholarSeed AI Team, Caoqinwei Gong, Xue Jiang, Wei Luo, Xiaoyu Qiu, Jiayi Sheng, Yi Wang, Zheng Yu, Ao Zhang, Haifan Zhang, Hanwei Zhang, Jihai Zhang, Yuan Cao, Wei Chen, Liyun Dai, Wenkai Fang, Guanglei Wang, Kai Ying, Tingyu Zhu, Wotao Yin
arXiv Computation and Language
Sep 11

INDRA: A New AI Tool for Exploring Tobacco, Fossil Fuel, and Chemical Industry Archives

INDRA is a research platform that integrates multiple archival collections—such as UCSF’s Industry Documents Library, Columbia and CUNY’s ToxicDocs, and Stanford’s SRITA—into a single, LLM‑readable corpus. It employs three safeguards: a closed evidentiary sandbox, real‑time provenance tagging, and a deterministic system‑level protocol to ensure that model outputs are clearly distinguished from archival evidence and from the model’s own inferences. The platform enables large‑language‑model‑powered investigations across these archives while keeping the conditions of knowledge production transparent and auditable.

By Daniel Akselrad, Robert N. Proctor
arXiv AI
3d ago

Large Knowledge Model: A Knowledge Foundation for Agentic Science at Scale

arXiv:2609.27297v2 Announce Type: replace Abstract: Agentic science envisions many autonomous agents investigating concurrently while building on a shared, evolving body of scientific knowledge. This...

By Yuan Huang, Sihan Hu, Hongyu Gu, Chao Ma, Jiaxing Zhang, Zhiyong Zou, Caiyu Fan, Yan Xiao, Mingjun Xu, Chenyu Xie, Mingzhen Ju, Zhehao Ma, Qi Zhang, Baozong Wang, Yu Li, Zhiyuan Yao, Ruoxue Liao, Xinyu Li, Linfeng Zhang, Kun Chen, Weinan E
arXiv AI
Sep 24

Large Knowledge Model: From Papers to a Scientific Reasoning Landscape

The paper introduces the Large Knowledge Model (LKM), a scientific knowledge infrastructure that converts research literature into shared, computationally accessible reasoning graphs. LKM aligns questions, claims, and reasoning chains across papers, creating a Scientific Reasoning Landscape with Question, Workflow, and Evidence views. The system enhances scientific search, evidence‑grounded QA, and research planning, achieving notable accuracy gains on ChemBench, PubMedQA, and SciBench.

By Yuan Huang, Sihan Hu, Hongyu Gu, Chao Ma, Jiaxing Zhang, Zhiyong Zou, Caiyu Fan, Yan Xiao, Mingjun Xu, Chenyu Xie, Mingzhen Ju, Zhehao Ma, Qi Zhang, Baozong Wang, Yu Li, Zhiyuan Yao, Ruoxue Liao, Xinyu Li, Linfeng Zhang, Kun Chen, Weinan E
arXiv AI
3d ago

PathAnchor: Path-Structured Evidence for Scientific Agents

PathAnchor is a new scientific reasoning system that uses path-structured evidence workspaces instead of independent passages or concepts. It retrieves source-linked Material‑Sensor‑Signal‑System trajectories that preserve role, direction, and supporting evidence, and a controller uses read‑only tools to search, trace, and open exact evidence before producing a claim‑cited answer. In evaluations on 120 flexible‑sensor questions, PathAnchor achieved an 82.6% score, outperformed six other systems, and improved source recall, citation completeness, and reduced tool calls compared to unordered concept graphs.

By Qiuhui Chen, Jiafan Lu, Shuaimin Tang, Tao Dai, Suyuan Wang, Chenrui Ji, Zhenglei Zhou, Weimin Zhong
arXiv AI
Sep 16

AquiLLM: Evaluating Faithfulness in Open-Weight RAG-LLM Systems for Scientific Research

arXiv:2609.16519v1 Announce Type: new Abstract: Scientific research increasingly relies on large, heterogeneous data sources, motivating interest in retrieval-augmented generation (RAG) systems that...

By Bernie Boscoe, Srinath Saikrishnan, Vikram Seenivasan, Jack Stark, Andrew Lizarraga, Morgan Himes, Jonathan Soriano, PJ Allen, Tuan Do
arXiv AI
Sep 12

From Document Silos to Process Intelligence: A Multi-Layer Knowledge Graph for CMC Process Development

The paper introduces a modular agentic-AI platform that transforms heterogeneous CMC process-development documents into a dual-layer knowledge graph. The base layer creates a lexical Document‑Section‑Chunk hierarchy, while the intelligence layer extracts ontology‑aligned entities and links cross‑document concepts, all anchored by provenance. LLM agents navigate these layers to answer queries, and a novel three‑tier evaluation protocol demonstrates high retrieval‑augmented generation performance on proprietary data from a Sanofi program.

By Reza Amirmoshiri, Faryad Sahneh, Yasser Jangjou
arXiv AI
Jul 28

VecTree-RAG: An Agentic Retrieval-Augmented Generation Framework Combining Vector and Tree Retrieval for Efficiency and Accuracy

arXiv:2607. 23006v1 Announce Type: cross Abstract: Scientific question answering requires a retrieval system to solve two distinct problems: identifying which papers are relevant and locating the supporting evidence within those papers.

By Xinyan Zhong, Yuwei Shi, Yuqi Wei, Chen Shen, Tianhang Zhou, Zhenghao Wu