arXiv AI By Haoyuan Li, Mathias Funk, Aaqib Saeed

Beyond Federated Learning: Decentralized Agentic Systems for Self-Evolving Clinical Intelligence

Read the original on arXiv AI →

The Flow has not summarised this story yet — read it at arXiv AI.

arXiv AI
Aug 25

MACD: Multi-Agent Clinical Diagnosis with Self-Learned Knowledge for LLM

The paper introduces MACD, a Multi-Agent Clinical Diagnosis framework that enables large language models to self‑learn clinical knowledge through a multi‑agent pipeline of summarization, refinement, and application. MACD is extended into a human‑AI collaborative workflow where multiple diagnostician agents consult iteratively, guided by a judge agent and human oversight. Evaluation on the MIMIC‑MACD cohort shows significant gains in diagnostic accuracy—an average 11.6 percentage‑point improvement over authoritative knowledge for open‑weight LLMs and an 18.3‑percentage‑point boost over physician‑only diagnosis in text‑only vignettes.

By Wenliang Li, Rui Yan, Xu Zhang, Li Chen, Hongji Zhu, Jing Zhao, Junjun Li, Mengru Li, Wei Cao, Zihang Jiang, Wei Wei, Kun Zhang, Shaohua Kevin Zhou
arXiv AI
Aug 26

CoMMa: Contribution-Aware Medical Multi-Agents for Decentralized Oncology Decision Support

CoMMa is a decentralized large language model (LLM) agent framework designed for oncology decision support. It allows specialists to work on partitioned clinical data streams, enforcing data decentralization and enhancing role specialization through agent-specific fine‑tuning. The framework introduces a contribution‑aware aggregation mechanism that replaces stochastic reasoning with deterministic embedding projections, enabling explicit credit assignment and a stable, interpretable decision pathway.

By Yichen Wu, Kailong Fan, Sangjoon Park, Yuhan Liu, Zhiyi Shi, Sekeun Kim, Dania Daye, Hana Farzaneh, Xiang Li, Raul Uppot, Yujin Oh, Quanzheng Li
arXiv Machine Learning
Sep 4

A cautionary tale on the cost-effectiveness of collaborative AI in real-world medical applications

The paper evaluates the cost‑effectiveness of consensus‑based learning (CBL) versus federated learning (FL) across seven medical datasets, three tasks, and eight modalities involving 3 to 23 clients. CBL achieves accuracy comparable to FL while dramatically cutting training time (15‑fold) and communication cost (60‑fold). The study suggests that CBL offers a more sustainable and democratized approach to deploying collaborative AI in real‑world healthcare settings.

By Francesco Cremonesi, Lucia Innocenti, Sebastien Ourselin, Vicky Goh, Michela Antonelli, Marco Lorenzi