arXiv AI By Siyao Wang, Florian Guitton, Shuojie Fu, Guanyu Tao, Kai Sun, Wenjia Bai

LongAgent: History-Guided Agentic Search for Longitudinal Outcome Prediction

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LongAgent is an agent-based method designed to extract predictive representations from heterogeneous longitudinal medical data. It autonomously searches over variable sets, temporal windows, and aggregation functions, using a history memory to guide exploration. On synthetic data, it achieves a mean prediction RMSE of 1.7376, outperforming the best non-agent baseline by 0.0151, and performs comparably to the best baseline on a real clinical dataset.

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