arXiv:2605. 00527v3 Announce Type: replace-cross Abstract: Lissajous confocal laser endomicroscopy (CLE) is a promising solution for high-speed in vivo optical biopsy for handheld scenarios.
arXiv:2609.15669v1 Announce Type: cross Abstract: Multimodal image registration is a key component of many clinical workflows, yet it remains challenging because corresponding anatomical structures o...
Multimodal image registration is a key component of many clinical workflows, yet it remains challenging because corresponding anatomical structures often exhibit substantially different image intensit...
arXiv:2511. 03826v4 Announce Type: replace-cross Abstract: Accurate and efficient registration of whole slide images (WSIs) is essential for high-resolution, nuclei-level analysis in multi-stained tissue slides.
C3VDReg is a benchmark for local-to-local colonoscopic registration that uses the Colonoscopy 3D Video Dataset (C3VD) to generate 10,015 partial-to-partial point cloud pairs, with 2,088 held‑out test pairs. Each pair consists of a source point cloud from depth reprojection and a target point cloud from CT mesh raycasting, evaluated under a standardized protocol of 8,192 points per cloud and fixed pose conventions. Experiments show that high geometric overlap does not guarantee reliable pose recovery, revealing translation ambiguity along repetitive tubular anatomy as a key failure mode.
arXiv:2410.14083v2 Announce Type: replace Abstract: This paper describes a new spatial correspondence representation based on paired regions-of-interest (ROIs), for medical image registration. The di...
The paper investigates test‑time adaptation (TTA) techniques for 3D point‑cloud registration in laparoscopic surgery, where synthetic training data must be adapted to noisy, sparse, and occluded real intraoperative reconstructions. It adapts three families of TTA methods—model, normalization, and input adaptation—to handle asymmetric shifts between preoperative meshes and intraoperative clouds, replacing classification‑based entropy objectives with correspondence‑based ones. Experiments on synthetic and real targets show that input adaptation consistently reduces registration error with low inference latency, making it the most promising approach for surgical applications.
Domain Elastic Transform (DET) is a grid‑free, probabilistic framework that jointly aligns geometry and high‑dimensional vector‑valued functions on irregular sparse manifolds, such as those found in spatial transcriptomics. By treating data as functions rather than voxelized images, DET performs unsupervised, scalable registration through sampled point alignment and displacement interpolation, guided by a joint spatial‑functional Bayesian likelihood. Evaluations on MERFISH mouse‑brain slices and Stereo‑seq mouse‑embryo atlases show DET achieving superior spatial overlap and topology compared to existing pipelines, with an accelerated variant delivering high label‑transfer accuracy.
The paper examines how residual misalignments from registration procedures introduce structured label noise in supervised synthetic CT (sCT) generation. It shows that voxel‑wise metrics are heavily influenced by the consistency between training and evaluation registrations, and that training with anatomically consistent registrations reduces variability and improves robustness. Introducing a perceptual loss based on a pretrained Segment Anything encoder yields sharper, more anatomically coherent sCT and highlights the need for anatomy‑oriented evaluation.
UniReg is a conditional unified model for medical image registration that adapts deformation field estimation based on anatomical priors, registration type constraints, and instance-specific features. It combines the precision of task‑specific learning with the generalization of traditional optimization, enabling effective alignment across diverse CT and MR scenarios within a single framework. Experiments show UniReg outperforms state‑of‑the‑art learning‑based methods in accuracy while providing strong cross‑scenario generalization and reducing training cost and model redundancy.
Monocular colonoscopic 3D reconstruction is important for surgical robotic colonoscopy, but remains challenging due to weak texture, specular reflections, limited view overlap, and non-rigid tissue mo...
arXiv:2609.23961v1 Announce Type: new Abstract: Monocular colonoscopic 3D reconstruction is important for surgical robotic colonoscopy, but remains challenging due to weak texture, specular reflectio...