The paper presents Libo Zhang’s algorithmic solution for the autoPETV Grand Challenge, focusing on interactive lesion segmentation in whole-body PET/CT scans. The method encodes user scribbles as two additional input channels and trains a large residual‑encoder U‑Net (≈140 M parameters) through a three‑phase curriculum over 4000 epochs, progressively moving from fully automatic segmentation to handling user‑provided scribbles and finally correcting its own mistakes via simulated error‑driven steps. Using 1811 studies for training and an ensemble of five‑fold checkpoints, the approach achieves a mean AUC‑Dice of 3.836 and a mean AUC‑DMM of 3.869 in interactive five‑fold cross‑validation, with significant gains from the first corrective scribble.
By Libo Zhang
arXiv:2608.30844v1 Announce Type: cross
Abstract: Interactive lesion segmentation in whole-body PET/CT requires a model to provide a strong initial prediction while also responding efficiently to spa...
By Xinglong Liang, Chunyao Lu, Tianyu Zhang, Jiaju Huang, Tao Tan, Yunchao Yin, Lishan Cai
The paper introduces an anatomy-aware, promptable segmentation model for whole-body lesion detection in FDG and PSMA PET/CT scans, tailored for the AUTOPET V challenge. The approach builds on nnU-Net, employing a two-stage training process: an initial pre-training phase for strong baseline segmentation and an online interactive phase that refines predictions using scribble prompts. Anatomical context is integrated via organ supervision with a shared head predicting both lesions and organs, reducing false positives, while a tracer classifier directs studies to either a combined FDG+PSMA model or a PSMA-specific model. Cross-validation results show that organ-supervised training yields the most stable performance, the interactive stage consistently improves Dice scores, and PSMA-specific training delivers the best tracer-wise results.
By Pablo Lozano-Jimenez, Sergio Romero-Tapiador, Ruben Tolosana
The paper introduces the first adaptation of the MedSAM2 foundation model for interactive 3D segmentation of interstitial lung disease (ILD) on thoracic CT scans. It evaluates three fine‑tuning strategies and four prompt types—bounding‑boxes, points, lassos, and scribbles—finding that full model fine‑tuning yields the best performance, improving Dice scores by 4.7 percentage points over the baseline. A proof‑of‑concept workflow is presented where MedSAM2 is first initialized with an automatic prior and then refined by radiologist prompts, with all resources released on GitHub.
By Vasilis Dedousis, Lubnaa Abdur Rahman, Lorenzo Brigat{\omicron}, Ethan Dack, Andreas Christe, Christoph Frank, Manuela Funke-Chambour, Justus Roos, Adrian Huber, Lukas Ebner, Stavroula Mougiakakou
arXiv:2606. 28392v1 Announce Type: cross Abstract: Accurate lesion segmentation in PET/CT is critical for oncology, yet remains challenging because physiologic tracer uptake and artifacts can mimic malignant signal.
By Jiasheng Wang, Tanun Jitwatcharakomol, Piyawadee Jongpradubgiat, Simeng Zhu
arXiv:2607. 25164v1 Announce Type: cross Abstract: A CT examination captures multiple organs, but many biomedical questions concern abnormalities, prognosis, or longitudinal change in a specific organ.
By Zhixuan Ge, Anqi Li, Sadeer Al-Kindi, Hanwen Xu, Wei Qiu
DALE-CT introduces depth‑aware 2D slice encoders that learn an anatomical world model of chest CT scans without 3D or positional supervision. By sampling self‑supervised views across a physical $z$‑axis slab, the encoder captures how anatomy changes between neighboring slices, enabling it to recover slice ordering and distinguish slices by anatomy alone. The model, trained on a large 287k‑scan corpus, achieves state‑of‑the‑art performance on CT‑RATE and is released with full code and evaluation tools.
By Evan W. Damron, Mahmut S. Gokmen, Mitchell A. Klusty, Caroline N. Leach, Emily B. Collier, V. K. Cody Bumgardner
arXiv:2606. 04365v1 Announce Type: cross Abstract: Radiology reports describe kidney lesions by type, size, enhancement, and attenuation, yet existing 3D methods predict only at the patient or organ level.
By Renjie Liang, Zhengkang Fan, Jinqian Pan, Chenkun Sun, Jiang Bian, Russell Terry, Jie Xu
arXiv:2608. 16377v1 Announce Type: cross Abstract: Instance-level lesion detection has been an increasingly larger focal point in medical image segmentation besides the more standard voxel-level overlap.
By Qinghui Liu, Jon Andr\'e Ottesen, Atle Bj{\o}rnerud, Kyrre Eeg Emblem
arXiv:2609.00473v1 Announce Type: cross
Abstract: Manual annotation remains a major bottleneck in ultrasound (US) bone segmentation, where experts typically iteratively refine rough brush masks rathe...
By Arash Tavangar, Larissa K. Chiu, Hamidreza Khodashenas, Gregory K. Berry, Amir Hooshiar
arXiv:2608. 05960v1 Announce Type: cross Abstract: Routine CT interpretation is inherently comprehensive, capturing incidental findings across the entire scan volume.
By Maulik Chevli, Johannes Brandt, Rickmer Braren, Daniel Rueckert, Philip M\"uller
arXiv:2608. 12086v1 Announce Type: cross Abstract: Vision-language models, such as contrastive language-image pre-training (CLIP)-based approaches, have reached state-of-the-art (SOTA) results in medical artificial intelligence.
By Nikolette Pedersen, Regitze Sydendal, Veronika Cheplygina, Th\'eo Sourget