Flexible Flows for Biological Sequence Design
arXiv:2606. 10543v1 Announce Type: cross Abstract: Designing functional biological sequences requires navigating vast discrete spaces under strict evolutionary and biophysical constraints.
arXiv:2606. 07400v1 Announce Type: new Abstract: Many scientific problems require inferring unobserved mechanistic latent states from indirect observations.
arXiv:2606. 10543v1 Announce Type: cross Abstract: Designing functional biological sequences requires navigating vast discrete spaces under strict evolutionary and biophysical constraints.
arXiv:2506. 03672v2 Announce Type: replace-cross Abstract: Combinatorial Optimization problems are widespread in domains such as logistics, manufacturing, and drug discovery, yet their NP-hard nature makes them computationally challenging.
arXiv:2606. 15458v1 Announce Type: cross Abstract: Variational inference (VI) is a core engine of modern AI, enabling scalable approximate Bayesian learning and uncertainty-aware training of large probabilistic and generative models.
arXiv:2606. 02133v1 Announce Type: cross Abstract: Non-monotonic sequence generation methods, such as masked diffusion models, provide a flexible alternative to left-to-right autoregressive modeling by allowing tokens to be generated in non-fixed and prescribed orders.
arXiv:2602. 17162v3 Announce Type: replace Abstract: Genomic Foundation Models (GFMs) typically rely on Masked Language Modeling (MLM) or Next-Token Prediction (NTP) to learn the "Laws of Nature".
arXiv:2606. 00934v1 Announce Type: cross Abstract: Network data are ubiquitous across the social sciences, biology, and information systems.
arXiv:2512. 09185v4 Announce Type: replace-cross Abstract: Understanding disease progression is a central clinical challenge with direct implications for early diagnosis and personalized treatment.
arXiv:2604. 01577v3 Announce Type: replace-cross Abstract: We study out of distribution generalization in streaming tasks where models are trained on short sequences but must operate over much longer, unknown horizons under bounded memory.
arXiv:2505. 04486v4 Announce Type: replace-cross Abstract: Flow matching models have shown great potential in image generation tasks among probabilistic generative models.
arXiv:2605. 16836v2 Announce Type: replace-cross Abstract: Hypergraphs provide a principled framework for modeling polyadic interactions, with applications in recommendation systems, social networks, and molecular modeling.
arXiv:2603. 19636v2 Announce Type: replace Abstract: Accurate RNA structure modeling remains difficult because RNA backbones are highly flexible, non-canonical interactions are prevalent, and experimentally determined 3D structures are comparatively scarce.
arXiv:2606. 27681v1 Announce Type: new Abstract: World models in partially observed environments rely on latent representations that summarize interaction history, but in many modern LLM-based architectures predictive performance fails to reflect representation quality due to history bypass, rendering the latent state unidentifiable.