arXiv:2604. 04287v2 Announce Type: replace Abstract: Foundation models in genomics have shown mixed success compared to their counterparts in natural language processing.
By Maxime Rochkoulets, Lovro Vr\v{c}ek, Mile \v{S}iki\'c
arXiv:2609.36952v1 Announce Type: cross
Abstract: Large language models (LLMs) excel at token-level generation but may learn undesirable abstract semantics and lack comprehensive perception. LLM-JEPA...
By Jingnan Pu, Zi-En Fan, Feng Lian
arXiv:2609.37675v1 Announce Type: new
Abstract: Protein Language Models (PLMs) have made remarkable progress following scaling laws established in natural language processing across sequence- and str...
By Biswajit Banerjee, Claudia Alvarez Carreno, Anton S. Petrov
arXiv:2606. 05173v1 Announce Type: cross Abstract: Masked language modelling (MLM) has been the dominant pre-training objective for text encoders since BERT, yet it encourages representations that are strongly anchored to surface-form token identity rather than deeper semantic structure.
By Aimen Boukhari
arXiv:2605.07938v2 Announce Type: replace
Abstract: Single-cell representation learning (SCRL) from gene expression data offers a way to uncover the complex regulatory logic underlying cellular funct...
By Sachini Weerasekara, Natasha Darras, Sagar Kamarthi, Colles Price, Jacqueline Isaacs
CellMSA introduces a novel single‑cell representation learning framework that leverages a multiple‑sequence‑alignment‑inspired context model. For each target cell, it retrieves relevant cells across batches and related cell types, summarizing cross‑cell patterns into a context‑dependent gene‑pair representation that is fed into a pair‑aware encoder. Pretraining on a massive human single‑cell corpus (≈109 million cells) and subsequent benchmarks demonstrate consistent performance gains over existing methods.
By Suyuan Zhao, Minghao Liu, Yizhen Luo, Zaiqing Nie