arXiv:2608. 08430v1 Announce Type: cross Abstract: Virtual cells employ machine learning models to simulate and predict cellular behaviors, serving as a critical computational framework for investigating health and disease.
arXiv:2509. 01916v2 Announce Type: replace Abstract: Causal disentanglement from soft interventions is identifiable under the assumptions of linear interventional faithfulness and availability of both observational and interventional data.
arXiv:2606. 24488v1 Announce Type: cross Abstract: Learning causal models from fragmented biomedical data is challenging because clinical, molecular, and imaging variables are often incomplete or not jointly observed.
arXiv:2606. 08816v1 Announce Type: cross Abstract: Predicting the effect of an unseen gene knockout perturbation on transcriptomic gene expression remains a highly challenging problem for virtual cell models.
arXiv:2605. 07267v2 Announce Type: replace Abstract: Personalized healthcare decisions require reasoning about how physiological and behavioral variables influence an individual patient over time.
arXiv:2606. 06440v1 Announce Type: new Abstract: Data-driven causal relationship identification is pertinent to advancing understanding of complex systems both within and beyond science.
arXiv:2606. 01042v1 Announce Type: cross Abstract: Perturbation experiments are central to understanding cellular mechanisms, but remain costly and sparse, motivating prediction of gene expression responses for unobserved conditions.
arXiv:2606. 18287v1 Announce Type: new Abstract: Multimodal neuroimaging, integrating functional connectivity from fMRI and structural connectivity from DTI, enables non-invasive analysis of brain networks using graph neural networks.
arXiv:2606. 05972v1 Announce Type: new Abstract: Causal graphs provide a high-level language for making mechanisms transparent.
arXiv:2607. 11510v1 Announce Type: new Abstract: Causal discovery from observational tabular data remains fundamentally challenging, primarily due to the heterogeneity of underlying causal mechanisms and the high-dimensional combinatorial search space of Directed Acyclic Graphs (DAGs).
arXiv:2607. 21859v2 Announce Type: replace Abstract: Constructing causal directed acyclic graphs (DAGs) is a core step in biomedical causal analysis, yet it remains a largely manual process.
arXiv:2608. 06824v1 Announce Type: cross Abstract: A central task in virtual cell modeling is predicting single-cell transcriptional responses to unseen genetic perturbations and drug combinations, and biological networks provide valuable priors on gene relationships.
arXiv:2608. 12640v1 Announce Type: cross Abstract: Causal discovery aims to uncover the underlying causal relationships given data generated from a system.