arXiv AI

OpenMedQ: Broad Open Pretraining for Medical Vision-Language Models

arXiv:2606. 12953v1 Announce Type: new Abstract: We present OpenMedQ, a medical vision-language model pretrained on the broadest fully-open medical mix to date: 14 datasets totaling ~3.

arXiv AI
Jun 11

OpenMedReason: Scientific Reasoning Supervision for Medical Vision-Language Models

arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.

By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv AI
Jun 8

MMBU: A Massive Multi-modal Biomedical Understanding Benchmark to Probe the Perception Capabilities of Vision-Language Models

arXiv:2606. 06696v1 Announce Type: cross Abstract: Vision and language models (VLMs) hold immense promise to transform biomedical imaging workflows, from detecting lesions in chest X-rays to profiling cellular features in microscopy.

By Ryan D'Cunha, Alejandro Lozano, Xiaoxiao Sun, Daniel Vela Jarquin, Min Woo Sun, Josiah Aklilu, James Burgess, Yuhui Zhang, Ryan Nayebi, Paola Avila, Robayo, Jin Ye, Ming Hu, Zhongying Deng, Junjun He, Xin Chen, Yue Yao, Robert Tibshirani, Jeffrey J. Nirschl, Serena Yeung-Levy
arXiv Computer Vision
Sep 17

Lumen: Parameter-Efficient Alignment of Pretrained Vision and Language Encoders for Zero-Shot Computational Pathology

Lumen is a pathology vision‑language model that aligns frozen unimodal foundation models (Virchow2 and BioMedBERT) using rank‑4 adapters and projection heads, training only 0.40% of the total parameters on the QUILT‑1M corpus. It achieves the highest mean chance‑corrected balanced accuracy (0.546) across nine zero‑shot patch benchmarks and demonstrates strong performance on lymph‑node metastasis detection, with AUROC scores of 0.964 internally and 0.955 externally. While it ranks third in cross‑modal retrieval, Lumen’s low‑parameter training yields competitive results at both patch and slide levels.

By Kiarash Tajbakhsh, Abdelrahman Faqieh, Michael Jopiti, Javier Garcia-Baroja, Philipp Zens, Branislav Zagrapan, Yuri Tolkach, Martin D. Berger, Aurel Perren, Bastian Dislich, Inti Zlobec, Amjad Khan
arXiv Computer Vision
Sep 7

Solve the Missing First Step: Can VLMs Standardize Raw Heterogeneous Medical Data?

The paper introduces the Medical Data Standardization Benchmark (MDS‑Bench), which evaluates vision‑language models (VLMs) on their ability to process raw, heterogeneous medical data. Models must identify source formats, convert raw images into VLM‑compatible inputs, extract relevant text, and organize the results into structured image‑text pairs. Experiments show that even the top VLM, Gemini 3 Flash, achieves only a 48.6% end‑to‑end success rate, underscoring the challenge of raw data standardization in clinical settings.

By Xin Chen, Dongliang Xu, Cunhao Zhu, Xudong Luo, Haoyang Lyu, Xiaoxiao Sun, Serena Yeung-Levy, Yue Yao
arXiv Computation and Language
Sep 22

MedGPT-oss: Training a General-Purpose Vision-Language Model for Biomedicine

arXiv:2603.00842v2 Announce Type: replace Abstract: Biomedical multimodal assistants have the potential to unify radiology, pathology, and clinical-text reasoning, yet a critical deployment gap remai...

By Kai Zhang, Zhengqing Yuan, Cheng Peng, Songlin Zhao, Mengxian Lyu, Ziyi Chen, Yanfang Ye, Wei Liu, Ying Zhang, Kaleb E Smith, Lifang He, Lichao Sun, Yonghui Wu
arXiv AI
Aug 20

MedUAG: Unified Understanding and Generation for Medical Multimodal Models

The paper introduces MedUAG, a unified medical multimodal model that supports both understanding and generation tasks. It presents MedUAGCorpus, the largest dataset of over 6 million instances across 14 imaging modalities, and MedUAGBench, a benchmark covering 12 diverse generation tasks with standardized protocols. Experiments show that MedUAG performs strongly across many medical understanding and generation tasks, setting a competitive baseline for future medical multimodal systems.

By Zijie Meng, Yuncheng Zhang, Hualiang Wang, Yitian Tang, Xiaotang Gai, Chen Shen, Songtao Jiang, Shaosheng Cao, Jian Wu, Xian Wu, Zuozhu Liu
arXiv AI
Jun 24

HiPath: Hierarchical Vision-Language Alignment for Structured Pathology Report Prediction

arXiv:2603. 19957v2 Announce Type: replace-cross Abstract: Pathology reports are structured, multi-granular documents encoding diagnostic conclusions, histological grades, and ancillary test results across one or more anatomical sites; yet existing pathology vision-language models (VLMs) reduce this output to a flat label or free-form text.

By Ruicheng Yuan, Zhenxuan Zhang, Anbang Wang, Liwei Hu, Xiangqian Hua, Yaya Peng, Jiawei Luo, Guang Yang