arXiv:2607. 04344v1 Announce Type: cross Abstract: While Large Vision-Language Models (VLMs) demonstrate remarkable generic capabilities, their clinical reasoning in specialized domains like ocular surface diseases (OSDs) is severely hindered by a paucity of high-fidelity, multimodal instruction-tuning data.
By Hao Wei, Wenjin Qi, Dasen Dai, Minqing Zhang, Wu Yuan
arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.
By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv:2607. 24743v1 Announce Type: cross Abstract: Multimodal large language models (MLLMs) hold immense potential to revolutionize clinical practice, yet deploying them in the medical domain is fundamentally a vision-centric challenge: models must absorb knowledge from heterogeneous 2D and 3D medical images, and evaluation protocols must align with radiologists' clinical practice and provide an accurate, fine-grained and factualness-driven assessment.
By Hangjie Yuan, Yichen Qian, Zhiwei Tang, Xianzhe Xu, Lirong Wu, Sicheng Yang, Jinwang Wang, Pengju Wang, Zhitao Zeng, Yizeng Han, Yan Xing, Shengxuan Luo, Tao Feng, Qing Xie, Weigen Yao, Yi Yang, Zuozhu Liu, Jiasheng Tang, Shaocheng Wang, Jitao Wang, Jiahong Dong, Weihua Chen, Feng Xu, Fan Wang
Multimodal large language models (MLLMs) hold immense potential to revolutionize clinical practice, yet deploying them in the medical domain is fundamentally a vision-centric challenge: models must absorb knowledge from heterogeneous 2D and 3D medical images, and evaluation protocols must align with radiologists' clinical practice and provide an accurate, fine-grained and factualness-driven assessment. In this paper, we introduce ClinFusion, a vision-centric MLLM designed for holistic medical understanding that systematically addresses these limitations.
The paper introduces MedUAG, a unified medical multimodal model that supports both understanding and generation tasks. It presents MedUAGCorpus, the largest dataset of over 6 million instances across 14 imaging modalities, and MedUAGBench, a benchmark covering 12 diverse generation tasks with standardized protocols. Experiments show that MedUAG performs strongly across many medical understanding and generation tasks, setting a competitive baseline for future medical multimodal systems.
By Zijie Meng, Yuncheng Zhang, Hualiang Wang, Yitian Tang, Xiaotang Gai, Chen Shen, Songtao Jiang, Shaosheng Cao, Jian Wu, Xian Wu, Zuozhu Liu
LiteMedCoT-VL is a parameter‑efficient pipeline that transfers chain‑of‑thought reasoning from a 235B teacher model to a 2B student model using LoRA fine‑tuning on explanation‑enriched data. The approach enables a compact vision‑language model to perform medical visual question answering without relying on image captions, achieving 64.9% accuracy on the PMC‑VQA benchmark—an 11‑point improvement over the zero‑shot Qwen3‑VL‑4B baseline. Visual grounding analysis confirms that the model bases its predictions on image content rather than textual priors.
By Runze Ma, Shunbo Jia, Haonan Lyu, Guo Liu, Caizhi Liao
The paper introduces ThoughtMed-1M, a large-scale medical visual question answering dataset built from de‑identified images and clinician‑generated commentaries, designed to capture structured clinical reasoning and image‑text alignment. Using this dataset, the authors train FOLTMed, a foundational large language model that achieves state‑of‑the‑art performance on 42 medical VQA benchmarks, with a macro accuracy of 85.4% and improved factuality and similarity metrics over existing models.
By Lingxuan Hou, Yuhua Xie, Yue Hu, Yan Zhuang, Junqi Li, Chengzhi Xia, Binh Phu Nguyen, Abubakar Siddique, Minh Nguyen, Yao Hou, Yanju Bao, Kexin Liu, Ke Chen, Jianjun Sun, Zeqi Li, Trung Nguyen, Jiangli Lin
arXiv:2603.02790v2 Announce Type: replace
Abstract: Foundation models are changing the way we develop medical artificial intelligence. By learning broadly generalizable features across diverse data m...
By Michelle Stegeman (and on behalf of the UNICORN consortium), Lena Philipp (and on behalf of the UNICORN consortium), Fennie van der Graaf (and on behalf of the UNICORN consortium), Marina D'Amato (and on behalf of the UNICORN consortium), Cl\'ement Grisi (and on behalf of the UNICORN consortium), Luc Builtjes (and on behalf of the UNICORN consortium), Joeran S. Bosma (and on behalf of the UNICORN consortium), Judith Lefkes (and on behalf of the UNICORN consortium), Rianne A. Weber (and on behalf of the UNICORN consortium), James A. Meakin (and on behalf of the UNICORN consortium), Thomas Koopman (and on behalf of the UNICORN consortium), Anne Mickan (and on behalf of the UNICORN consortium), Mathias Prokop (and on behalf of the UNICORN consortium), Ewoud J. Smit (and on behalf of the UNICORN consortium), Fr\'ed\'erique Meeuwsen (and on behalf of the UNICORN consortium), Geert Litjens (and on behalf of the UNICORN consortium), Jeroen van der Laak (and on behalf of the UNICORN consortium), Bram van Ginneken (and on behalf of the UNICORN consortium), Maarten de Rooij (and on behalf of the UNICORN consortium), Henkjan Huisman (and on behalf of the UNICORN consortium), Colin Jacobs (and on behalf of the UNICORN consortium), Francesco Ciompi (and on behalf of the UNICORN consortium), Alessa Hering (and on behalf of the UNICORN consortium)
Lingshu is a medical‑specialized multimodal large language model that addresses key limitations of existing medical MLLMs, such as narrow knowledge coverage, hallucinations, and weak reasoning. The authors curate a comprehensive dataset combining medical imaging, texts, and general‑domain data, then train Lingshu in multiple stages to embed medical expertise and improve task performance. They also introduce MedEvalKit, a unified evaluation framework, and demonstrate that Lingshu outperforms current open‑source multimodal models on multimodal QA, text‑based QA, and medical report generation.
By Weiwen Xu, Hou Pong Chan, Long Li, Mahani Aljunied, Ruifeng Yuan, Jianyu Wang, Chenghao Xiao, Guizhen Chen, Chaoqun Liu, Zhaodonghui Li, Yu Sun, Junao Shen, Chaojun Wang, Jie Tan, Deli Zhao, Tingyang Xu, Hao Zhang, Yu Rong
arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.
By Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Anchal Nema, Nivedita Wadhwa, Prashams S Jain, Rebecca Abraham, Will Kimbrough, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
arXiv:2607.12896v3 Announce Type: replace
Abstract: Medical image segmentation foundation models are expected to generalize across diverse clinical scenarios, yet existing universal methods remain fr...
By Yunzhou Li, Jiesi Hu, Yanwu Yang, Hanyang Peng, Chenfei Ye, Jianfeng Cao, Yixuan Yuan, Ting Ma
arXiv:2604.16729v2 Announce Type: replace-cross
Abstract: State-of-the-art large language models (LLMs) show high performance in general visual question answering. However, a fundamental limitation r...
By Ayhan Can Erdur, Daniel Scholz, Jiazhen Pan, Benedikt Wiestler, Daniel Rueckert, Jan C. Peeken