Background/Objectives: Dermoscopic skin lesion classifiers often lose accuracy under domain shift across imaging devices, illumination, and capture artifacts. We study how data augmentation improves the robustness of a binary malignant-versus-non-malignant classifier, with emphasis on out-of-domain (OOD) generalization.
arXiv:2606. 13135v1 Announce Type: cross Abstract: Purpose.
By Elena S. Kozachok, Sergey S. Seregin, Aleksandr V. Kozachok, Ilya P. Latyshev, Oleg I. Samovarov
arXiv:2609.36400v1 Announce Type: cross
Abstract: Deep learning classifiers for dermoscopic skin lesions often reach high in-distribution accuracy while quietly relying on spurious background cues su...
By Youssef Attia, Debasmita Mukherjee
The study examines why dermatology AI models, largely trained on light‑skinned, cancer‑focused images, perform poorly when applied to diverse patient populations. By comparing a cancer‑trained baseline, two dermatology foundation models, and a general‑purpose vision model on tone‑stratified and disease‑shifted datasets, the authors find that disease‑distribution shift, rather than skin‑tone underrepresentation, is the primary cause of generalization failure. Representation analysis shows that cancer‑specialized features lack transferable structure, while dermatology‑pretrained features maintain stronger clustering, and lightweight adaptation with about ten labeled examples per category can recover most performance.
By Nirajan Kunwor, Sanjaya Poudel, Quoc-Huy Trinh, Jahidul Arafat, Sunil Kumar Gaire
The paper introduces AdaConRed, a label‑free post‑conformal decision rule that transforms ambiguous conformal prediction sets into single class assignments for medical image classification. It employs a five‑stage pipeline—vision‑language generative augmentation, a frozen DermFoundation encoder, a lightweight MLP classifier, an entropy‑modulated margin‑aware nonconformity score, and a reassignment step for transitional samples—to improve accuracy on OSCC and ISIC benchmarks. Results show notable gains in malignant class accuracy while maintaining overall performance.
By Saibal Ghosh, Samarup Bhattacharya, Sanjoy Kumar Saha, Umapada Pal, Tapabrata Chakraborti
LENS‑GRF is a permutation‑invariant lesion evidence network that uses a Set‑Transformer and gated residual fusion to combine global facial context with localized lesion patches for four‑class acne severity grading. The framework integrates adaptive facial skin segmentation, a Vision Transformer prior, and a lesion set transformer that encodes spatial geometry, with a gating mechanism that modulates local residual contributions. In experiments on ACNE04 and PLSBRACNE01, the fully automated model achieved 80.82% accuracy, while using ground‑truth lesion annotations raised accuracy to 95.89% and a Quadratic Weighted Kappa of 0.9753; zero‑shot evaluation on the full cohort yielded 35.00% accuracy versus 42.50% for a global baseline, and oracle analyses on a 148‑subject cohort showed improved accuracy and QWK up to 47.97% and 0.5799.
By Muhammad Muhtasim Shahriar, M. F. Mridha
FedHisto-PAST v2 is a parameter‑efficient, stain‑aware federated learning framework for cross‑site lung histopathology classification, combining a frozen HIBOU‑B foundation model with techniques such as paired‑view prediction, feature consistency, prototype learning, and adaptive aggregation. In a five‑client, non‑IID simulation and an exploratory LungHist700 cohort, the method achieved a Macro‑F1 of 0.7286 and a balanced accuracy of 0.7305, with the prediction‑level consistency component providing the most clear independent benefit. The framework updated only about 1.25% of the model parameters, demonstrating efficient adaptation while acknowledging limitations in privacy guarantees and clinical validation.
By Muhammad Muhtasim Shahriar, M. M. Golam Hafiz, Saad Aloteibi, Mohammad Ali Moni
arXiv:2609.38560v1 Announce Type: new
Abstract: Mycosis fungoides (MF) is a rare form of cutaneous T-cell lymphoma that is often misdiagnosed in early stages due to its visual similarity to benign in...
By Mohamed Hazem, Tarek Waleed, Omar Khaled, Nada Omar, Mahmoud Raslan, Marwa Mohamed Fawzy, Aya Fahim, Rania M. Mogawer, Ahmed Mourad, Kariman Mansour, Muhammad Rushdi
MDSkin-Net is a multi‑task skin lesion analysis framework that integrates Pattern Analysis priors into a hybrid CNN‑Transformer architecture. It introduces a Pattern Analysis‑Guided Attention Module (PAGAM) with improved Efficient Channel Attention, Multi‑Scale Spatial Attention, and Biased Asymmetry Attention, along with a multi‑scale spatial alignment regularization that uses segmentation masks as soft supervision. Trained only on the ISIC 2017 training split, the model achieves high segmentation and classification performance on multiple datasets, demonstrating strong zero‑shot generalization across different cohorts.
By Yijian Li, Saad Bedros, Paul Bigliardi, Mei Bigliardi Qi, Vassilios Morellas, Nikolaos Papanikolopoulos
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
By Zhi Li (Caris Life Sciences, Irving, TX, United States), Eghbal Amidi (Caris Life Sciences, Irving, TX, United States), Yating Cheng (Caris Life Sciences, Irving, TX, United States), Tyson Dawson (Caris Life Sciences, Irving, TX, United States), Gorkem Can Ates (Caris Life Sciences, Irving, TX, United States), Shuzhen Kuang (Caris Life Sciences, Irving, TX, United States), Norsang Lama (Caris Life Sciences, Irving, TX, United States), Md Ashequr Rahman (Caris Life Sciences, Irving, TX, United States), Zhiying Lu (Caris Life Sciences, Irving, TX, United States), Elisabeth K. Kong (Caris Life Sciences, Irving, TX, United States), Milan Radovich (Caris Life Sciences, Irving, TX, United States), David Spetzler (Caris Life Sciences, Irving, TX, United States), Matthew Oberley (Caris Life Sciences, Irving, TX, United States), George W. Sledge (Caris Life Sciences, Irving, TX, United States), Ming Chen (Caris Life Sciences, Irving, TX, United States)
arXiv:2607. 12075v1 Announce Type: cross Abstract: Background: Deep learning models can classify thyroid nodules on ultrasound, but reliable clinical decision support also requires calibrated probabilities, uncertainty estimation, and selective referral, particularly under dataset shift.
By Md. Sadibul Hasan Sadib, Md. Mohayminul Mukit, Rahmatul Kabir Rasel Sarker, Tahmid Alam Tamim, Md. Monir Hossain Shimul
Accurate dermatological diagnosis naturally necessitates equitable performance across diverse populations, yet a systematic lack of expertly annotated images, especially for underrepresented skin tones and rare diseases, impedes progress toward measurably fair methods. We introduce cgDDI (Controllable Generation of Diverse Dermatological Imagery), a hybrid framework that (1) synthesizes realistic healthy skin samples without disturbing other input properties, (2) maps single-sample rare lesions onto novel skin-tones and locations non-parametrically, and (3) allows for efficient parametric generation with as few as 10 training samples.