arXiv AI

BioEVAL: A global, multi-institutional benchmark of large language and multimodal models for bioengineering

BioEVAL is a global, multi‑institutional benchmark that evaluates large language and multimodal models on experimental reasoning tasks in bioengineering. It comprises 608 items across 11 bioengineering subfields, including 359 vetted multiple‑choice questions, 218 literature synthesis tasks, and 10 multimodal image‑interpretation problems. The benchmark was used to assess models such as ChatGPT, Gemini, and Grok, revealing accuracies up to 90% on MCQs, a 0.72 similarity score on literature synthesis, and 80% accuracy on multimodal tasks, with notable variation across subfields.

arXiv AI
Sep 18

BioPhys-Bridge: A Benchmark for Interdisciplinary Scientific Reasoning in Physics-Grounded Biological Research

BioPhys-Bridge is a newly released benchmark dataset designed to evaluate language models on evidence‑grounded scientific reasoning within biophysical literature. Each of its 500 cases includes evidence blocks, stable IDs, quantitative values, units, equations, assumptions, mechanisms, and next‑step decisions, covering six biological domains and nine physical model families. The dataset enforces strict quality gates and has already been evaluated against several models, with DeepSeek‑V4‑Flash achieving the highest evidence‑ID F1 score of 0.360.

By Qingyang Xu
arXiv AI
Sep 12

Sci-MMR: Benchmarking Multi-Step Evidence-Grounded Scientific Reasoning in Multimodal Agents

Sci‑MMR is a new benchmark for multi‑step evidence‑grounded scientific reasoning in multimodal agents, featuring 235 multi‑hop tasks across four disciplines and an average of nine figure panels per task. It evaluates not just final answer accuracy but also the recovery of structured evidence from scientific claims, citations, visual data, and supporting regions. Experiments on eight state‑of‑the‑art models show a gap of over 20 points between answer accuracy and complete evidence recovery, highlighting significant challenges in evidence acquisition and integration.

By Jiaqiang Li, Yajie Yang, Zhiheng Xi, Jiadong Chen, Enyu Zhou, Senjie Jin, Yang Nan, Jiazheng Zhang, Han Wang, Yanxin Li, Dingwei Zhu, Bicheng Deng, Yuhui Wang, Xiang Zheng, Qi Zhang, Lei Bai, Xingjun Ma, Tao Gui
arXiv AI
2d ago

MatToolBench: Benchmarking Multimodal Agents in Real-World Materials Science Workflows

MatToolBench is a new benchmark that evaluates multimodal GUI agents on professional materials science software. It contains 204 tasks across 10 tools in three modalities—GUI operation, OriginPro scripting, and code-based database queries—executed inside a Windows 11 VM. The benchmark offers fine-grained, expert-decomposed scoring and a high-performing multimodal judge for aesthetic assessment, revealing that strong general benchmark performance does not transfer to scientific workflows.

By Mei Wu, Rui Xie, Runyu Zhang, Yuqiang Li, Tianfan Fu, Bo Chen, Kai Yu, Xin Chen, Lu Chen
arXiv AI
1d ago

OSWorld-Science: A Benchmark of Computer Use Agents for Learning and Using Scientific Software

OSWorld-Science is a benchmark and evaluation environment for computer-using agents that use visual language models (VLMs) to perform scientific software tasks. It includes 12 VLMs and 146 high-quality tasks across domains such as molecular drawing, pathology image analysis, statistical computing, and physical simulation, with artifact-based evaluation and a harness that logs interactions and supports model comparison. The benchmark was developed through expert proposals and iterative human–AI co‑design, and results show that current VLMs still struggle with key scientific questions, offering insights into factors like language, reasoning, and context length.

By Dingyuan Dai, Heli Qi, Lei Liu, Yinxi Li, Baiding Chen, Zijun Dou, Qingcheng Zeng, Qi Kang, Oliver Sun, Eric Wang, Bo Zhou, Haixin Wang, Yufan Du, Shi Bo, Ruihan Lin, Mengqi Yuan, Dunjie Lu, Steven Dillmann, Yiming Shi, Tina Su, Amy Xin, Minghao Liu, Xi Wang, Xu Huang, Ge Zhang, Pengyu Nie, Zhen Yang, Jie Tang, Juanzi Li, Weihao Xuan, Tianyu Liu
arXiv AI
Jun 24

BioMedArena: An Open-source Toolkit for Building and Evaluating Biomedical Deep Research Agents

arXiv:2605. 06177v2 Announce Type: replace Abstract: Reproducing and comparing deep research agents today is hard: the same backbone evaluated on the same benchmark can report different accuracies across papers because the harness and tool registry differ, and integrating a new model into a comparable evaluation surface costs weeks of model-specific engineering.

By Jinge Wu, Hongjian Zhou, Mingde Zeng, Jiayuan Zhu, Junde Wu, Jiazhen Pan, Ayush Noori, Sean Wu, Honghan Wu, Fenglin Liu, David A. Clifton
arXiv AI
Jun 8

MCERF: Advancing Multimodal LLM Evaluation of Engineering Documentation with Enhanced Retrieval

arXiv:2604. 09552v2 Announce Type: replace-cross Abstract: Engineering rulebooks and technical standards contain multimodal information like dense text, tables, and illustrations that are challenging for retrieval augmented generation (RAG) systems.

By Kiarash Naghavi Khanghah, Hoang Anh Nguyen, Anna C. Doris, Amir Mohammad Vahedi, Daniele Grandi, Faez Ahmed, Hongyi Xu
arXiv AI
Aug 3

M3MAD-Bench: Multi-Dimensional Evaluation of Multi-Agent Debate Across Domains and Modalities

arXiv:2601. 02854v2 Announce Type: replace Abstract: As an agent-level reasoning and coordination paradigm, Multi-Agent Debate (MAD) orchestrates multiple agents through structured debate to improve answer quality and support complex reasoning.

By Ao Li, Jinghui Zhang, Luyu Li, Yuxiang Duan, Lang Gao, Mingcai Chen, Weijun Qin, Shaopeng Li, Fengxian Ji, Ning Liu, Lizhen Cui, Xiuying Chen, Yuntao Du
arXiv AI
Jun 30

IMCBench: A benchmark for multimodal LLMs in Image-grounded Medical Conversations

arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.

By Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Anchal Nema, Nivedita Wadhwa, Prashams S Jain, Rebecca Abraham, Will Kimbrough, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
arXiv Computation and Language
Sep 22

Lingshu: A Generalist Foundation Model for Unified Multimodal Medical Understanding and Reasoning

Lingshu is a medical‑specialized multimodal large language model that addresses key limitations of existing medical MLLMs, such as narrow knowledge coverage, hallucinations, and weak reasoning. The authors curate a comprehensive dataset combining medical imaging, texts, and general‑domain data, then train Lingshu in multiple stages to embed medical expertise and improve task performance. They also introduce MedEvalKit, a unified evaluation framework, and demonstrate that Lingshu outperforms current open‑source multimodal models on multimodal QA, text‑based QA, and medical report generation.

By Weiwen Xu, Hou Pong Chan, Long Li, Mahani Aljunied, Ruifeng Yuan, Jianyu Wang, Chenghao Xiao, Guizhen Chen, Chaoqun Liu, Zhaodonghui Li, Yu Sun, Junao Shen, Chaojun Wang, Jie Tan, Deli Zhao, Tingyang Xu, Hao Zhang, Yu Rong
arXiv AI
1d ago

From Compound Figures to Medical Multi-image Reasoning: Scaling Multimodal Large Language Models with Biomedical Literature

arXiv:2511.22232v2 Announce Type: replace-cross Abstract: Multimodal large language models (MLLMs) are increasingly capable in medical imaging, yet most focus on single-image settings. Clinical inter...

By Zhen Chen, Yihang Fu, Rong Zhou, Serina Applebaum, Min Kyu Kim, Aidan Gilson, Morten Lee, Salahudeen Mirza, Gabriel Madera, Mauro Giuffre, Yuanting Pan, Roy Jiang, Hyunjae Kim, Hua Xu, Qingyu Chen
arXiv AI
2d ago

OmniVCBench: Benchmarking Evidence-Grounded Multimodal Reasoning Towards AI Virtual Cells

OmniVCBench is a figure‑centric, source‑traceable benchmark designed to evaluate the interpretation component of Artificial Intelligence Virtual Cells (AIVCs). It comprises 6,077 curated question–answer pairs drawn from scientific figures and experimental contexts, organized into three scientific reasoning tasks that mirror the AIVC Predict–Explain–Discover agenda. The benchmark also introduces AIVC‑Judge, a task‑conditioned MLLM‑as‑a‑judge framework with reference‑aware rubrics, and a Model‑Derived Hard‑Negative Mining strategy to generate multiple‑choice distractors for efficient evaluation.

By Manyu Li, Xunkai Li, Yongfu Xiong, Yi Liu, Rong-Hua Li, Guoren Wang