arXiv AI

FICAug: Feature-Informed Clustering and Augmentation for Facial-Expression-Based Parkinson's Disease Screening

arXiv Computer Vision
Sep 11

DINO-Med: A Unified Patch-Based Adaptation Framework for Multi-Modal Medical Image Analysis Applied to Liver Fibrosis Staging

DINO-Med introduces a patch‑based framework that adapts natural‑image foundation models, specifically DINOv3, to multi‑modal medical imaging. The method uses training‑free registration, automated localization, and mask‑filtered patch extraction to aggregate patch‑level features into subject‑level diagnostics. In liver fibrosis staging, DINOv3 outperforms handcrafted radiomics, ResNet, and SAM‑Med2D features, achieving 78.4% accuracy for mild fibrosis (S1) and 75.8% for cirrhosis (S4) on the CARE 2025 cohort.

By Boya Wang, Ruizhe Li, Chao Chen, Xin Chen
arXiv Machine Learning
Jun 8

Explaining Unsupervised Disease Staging in Huntington's Disease: Insights into Model Representations and Clusters

arXiv:2606. 07135v1 Announce Type: new Abstract: Huntington's disease (HD) is a progressive neurodegenerative disorder that affects motor, cognitive, and behavioral functions, where accurate characterization of disease progression remains essential to improve patient outcome and quality of life.

By Lubna Mahmoud Abu Zohair, Hind Zantout
Hugging Face Trending Papers
Sep 10

DINO-Med: A Unified Patch-Based Adaptation Framework for Multi-Modal Medical Image Analysis Applied to Liver Fibrosis Staging

The paper introduces DINO-Med, a patch‑based framework that adapts natural‑image foundation models to multi‑modal medical imaging, specifically for liver fibrosis staging. It processes raw multimodal scans through training‑free registration, automated localization, and mask‑filtered patch extraction, then aggregates patch‑level insights into subject‑level diagnostics. Using the CARE 2025 Liver Track 4 cohort, the DINOv3‑based approach achieved the highest classification accuracy (78.4% for mild fibrosis and 75.8% for cirrhosis) compared to other feature representations.

arXiv Machine Learning
Jun 18

ActiTect: A Generalizable Machine Learning Pipeline for REM Sleep Behavior Disorder Screening through Standardized Actigraphy

arXiv:2511. 05221v3 Announce Type: replace Abstract: Isolated rapid eye movement sleep behavior disorder (iRBD) is a major prodromal marker of $\alpha$-synucleinopathies, often preceding the clinical onset of Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy.

By David Bertram, Anja Ophey, Sinah R\"ottgen, Konstantin Kufer, Gereon R. Fink, Elke Kalbe, Clint Hansen, Walter Maetzler, Maximilian Kapsecker, Lara M. Reimer, Stephan Jonas, Andreas T. Damgaard, Natasha B. Bertelsen, Casper Skjaerbaek, Per Borghammer, Karolien Groenewald, Pietro-Luca Ratti, Michele T. Hu, No\'emie Moreau, Michael Sommerauer, Katarzyna Bozek
arXiv AI
Jun 30

Towards Modality-Agnostic Medical Image Anomaly Detection: A Training-Free Manifold Refinement Approach

arXiv:2604. 19191v2 Announce Type: replace-cross Abstract: Deploying AI-based anomaly detection across diverse clinical imaging settings remains challenging because most existing methods rely on modality-specific architectures, anatomical priors, or extensive retraining, limiting their use as general-purpose screening tools.

By Pritam Kar, Gouri Lakshmi S, Saptarshi Bej
arXiv AI
Jul 8

Hierarchical Classification via Cascading Feature Elimination: Application to Human Phenotype Ontology-Aligned Facial Phenotyping (FaceMesh2HPO)

arXiv:2607. 05585v1 Announce Type: cross Abstract: FaceMesh2HPO is a framework for classifying facial phenotypic descriptors aligned with the Human Phenotype Ontology (HPO) to support clinical diagnosis.

By Fabio Hellmann, Alexander Hustinx, Benjamin D. Solomon, GestaltMatcher Database Consortium, Tzung-Chien Hsieh, Peter Krawitz, Elisabeth Andr\'e
arXiv Computation and Language
Sep 21

Cross-Lingual Parkinson's Disease Severity Assessment Using Pre-trained Speech Embeddings: A Multi-Class Evaluation

The paper evaluates pre‑trained speech embeddings from four state‑of‑the‑art speech foundation models for cross‑lingual Parkinson's disease severity assessment. Experiments span three datasets in zero‑shot and k‑shot settings, showing that these embeddings can transfer meaningfully across languages, though performance varies with dataset characteristics, preprocessing, and adaptation strategy. Misclassifications linked to inter‑speaker variability and atypical speech patterns underscore the need for more robust feature extraction, modeling, and explainability to support reliable clinical insights.

By Simon Pals, Cristian Tejedor-Garcia
arXiv Machine Learning
Jul 22

Local Label-Informed Feature Transfer for Generating Ground-Truth Medical Images: A Comparison of GAN- and Diffusion-Based Approaches

arXiv:2607. 18882v1 Announce Type: cross Abstract: Validating Explainable Artificial Intelligence (XAI) methods in medical imaging requires ground-truth data with known locations of informative features.

By Rick Wilming, Irem Ozseker, Luca Matteo Cornils, Ahc\`ene Boubekki, Benedict Clark, Danny Panknin, Stefan Haufe