arXiv:2608. 14355v1 Announce Type: new Abstract: Spatial transcriptomics (ST) enables the simultaneous profiling of gene expression and tissue morphology, creating an opportunity to learn multimodal representations capturing shared morpho-transcriptomic structure.
By Julian Ostermaier, Swann Ruyter, Reuben Dorent, Daniel Racoceanu
The paper introduces MedIDL, a Medical Imaging Disentanglement Learning framework that separates disease-related features from confounding covariates and individual variability in medical images. It achieves this by projecting image features into three orthogonal latent spaces—disease classification, covariate alignment, and a Gaussian head for individual variation—using specialized disentanglement heads. Across seven diverse imaging datasets, MedIDL surpasses state‑of‑the‑art supervised and self‑supervised methods in classification accuracy, and its latent representations and gradient‑based visualizations align with known clinical patterns.
By Shengjie Zhang, Jinglin Zhang, Zhuangzhuang Jiang, Ziqi Yu, Yipin Zhang, Qi Zhang, Xiang Chen, Haibo Yang, Fei Gao, Longbiao Cui, Yuan Zhou, Xiao-Yong Zhang, Alzheimer's Disease Neuroimaging Initiative
arXiv:2509.22404v2 Announce Type: replace
Abstract: Anatomical understanding, which is the ability to identify, localize, or segment anatomical structures, is critical in medical image analysis; howe...
By Yiwei Li, Yikang Liu, Jiaqi Guo, Lin Zhao, Zheyuan Zhang, Xiao Chen, Boris Mailhe, Ankush Mukherjee, Terrence Chen, Shanhui Sun
arXiv:2607. 03103v1 Announce Type: cross Abstract: Clinical cardiac imaging pipelines currently deploy separate models for each dataset and modality, incurring redundant training costs and precluding knowledge sharing across anatomically related tasks.
By Jiahao Liu, Hang Wei, Shuai Wu
arXiv:2603.13044v2 Announce Type: replace-cross
Abstract: Medical image segmentation (MIS) is a fundamental component of computer-assisted diagnosis and clinical decision support. Over the past decad...
By Vanessa Borst, Anna Riedmann, Samuel Kounev
InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.
By Ziquan Liu, Zhewei Zhu, Xuyang Shi
arXiv:2608. 05960v1 Announce Type: cross Abstract: Routine CT interpretation is inherently comprehensive, capturing incidental findings across the entire scan volume.
By Maulik Chevli, Johannes Brandt, Rickmer Braren, Daniel Rueckert, Philip M\"uller
arXiv:2607.12896v3 Announce Type: replace
Abstract: Medical image segmentation foundation models are expected to generalize across diverse clinical scenarios, yet existing universal methods remain fr...
By Yunzhou Li, Jiesi Hu, Yanwu Yang, Hanyang Peng, Chenfei Ye, Jianfeng Cao, Yixuan Yuan, Ting Ma
arXiv:2605.30972v2 Announce Type: replace
Abstract: Accurate 3D medical image segmentation requires both fine spatial detail and long-range volumetric context. Although Mamba provides efficient long-...
By Bakht Zada, Chao Tong, Qile Su, Shuai Zhang
AlphaRAD introduces a grounded zero‑shot classification framework for chest radiology that leverages structured medical concepts extracted from reports and a novel α‑Corrected Binary Cross‑Entropy loss to reduce in‑batch noise. It also presents FLaS, a lightweight cross‑modal fusion module that factorizes VLPM representations into independent subspaces, improving spatial grounding without adding parameters. The method achieves state‑of‑the‑art performance on 16 classification benchmarks and sets new records on several grounding, phrase‑grounding, and segmentation datasets.
By Jianzhong You, Yuan Gao, Chris McIntosh
The paper introduces an unsupervised approach to medical image segmentation by training a Denoising Diffusion Probabilistic Model (DDPM) on 21 unlabeled abdominal CT scans to learn anatomical features. The encoder weights from the DDPM are transferred to a U‑Net for downstream segmentation on the BTCV multi‑organ dataset, resulting in a significant Dice score improvement for liver segmentation from 0.75 to 0.93. In low‑data regimes, diffusion‑pretrained models retain robust performance, achieving high Dice scores even with only 10% of labeled data.
By Akshat G, Divyansh Gupta, Shaleen Bhatnagar, Shilpa Ankalaki, Tusar Kanti Mishra
The growing number of medical vision foundation models highlights the need for effective model selection. However, mainstream selection methods rely on exhaustive fine-tuning, which is computationally expensive.