ASTAR is an LLM-based framework that automatically generates standardized radiology reporting templates from large-scale clinical free-text corpora, eliminating the manual, expert-driven template construction process. In experiments on 4,215 fetal brain MRI reports from multiple centers, ASTAR‑induced templates outperformed two expert‑curated templates in template coverage, information fidelity, diagnostic fidelity, and expert‑rated usability. The approach reduces template development time from weeks of committee deliberation to hours of automated processing.
By Xinfeng Zhang, Mingxuan Liu, Yifei Chen, Juncheng Zhu, Kasidit Anmahapong, Yiming Huang, Yuan Zhang, Hongjia Yang, Yi Liao, Gang Ning, Haibo Qu, Qiyuan Tian
Large language model assistants are being deployed to clinicians, but their readiness is judged mainly by benchmark scores that are based on examination questions or curated cases. This study analyzed 127,833 queries from 6,342 healthcare professionals across 35 specialties, finding that most requests were for documentation, administration, and knowledge retrieval, with a significant portion of queries unanswerable. When compared to 58 public benchmarks, the median benchmark lacked documentation requests and only shared 31% of the real task mix, indicating that current benchmarks poorly reflect actual clinical use.
By Krithik Vishwanath, Haitong Lin, Anton Alyakin, Jin Vivian Lee, D. Brock Hewitt, Jie J. Yao, William Robert Small, Hammad A. Khan, Cordelia Orillac, Aakaash Varma, Brandon Ye, Daniel Alexander Alber, Gustavo Stolovitzky, Batia Wiesenfeld, Oded Nov, Wei Wu, Kang Zhang, Yindalon Aphinyanaphongs, Tim Requarth, Eric Karl Oermann, The International Digital Twin Consortium in Healthcare, Medicine
arXiv:2601.16753v2 Announce Type: replace-cross
Abstract: Longitudinal information in radiology reports refers to the sequential tracking of findings across multiple examinations over time, which is...
By Xinyi Wang, Grazziela Figueredo, Ruizhe Li, Xin Chen
MeddeX is a medical report analyzer that fuses a QLoRA‑fine‑tuned LLaMA‑3 (8B) model with Retrieval‑Augmented Generation and a Gemini Vision layer to produce concise, evidence‑backed summaries of medical documents. It processes text‑native PDFs, scanned PDFs, and radiological images via a hybrid extraction pipeline featuring a garbage‑text detection mechanism for corrupted or UTF‑16‑encoded files. The system adds report‑scoped retrieval, an automated longitudinal comparison engine, and a self‑healing backfill pipeline, and is backed by a FastAPI backend, Supabase vector store, and Next.js frontend. Evaluation shows significant gains over the base LLaMA‑3‑Med42‑8B model across ROUGE, BLEU, and BERTScore metrics, underscoring the value of domain‑specific fine‑tuning.
By Rajdeep Pandhare, Rohit Kundaikar, Yakub Kojar, Shreyansh Tiwari
This thesis explores how to select and adapt NLP models for global health literature when annotated data and computational resources are scarce. It compares skip‑gram word2vec models trained on increasingly large specialized corpora with BioWordVec for semantic tag discovery, finding that larger coverage does not always yield more useful domain associations. The study also evaluates convolutional spaCy models versus a RoBERTa transformer for named entity recognition, noting a trade‑off between higher F1 scores and longer inference time, and investigates MiniLM few‑shot versus BART‑MNLI zero‑shot classification for multi‑label topic classification, highlighting practical constraints of inference cost.
"whyItMatters":"The work provides empirical guidance on balancing model accuracy and resource demands for building knowledge systems in low‑resource global health settings."
By Genis Skura, Antoine Geissb\"uhler, Jean-Luc Falcone
arXiv:2604. 25605v2 Announce Type: replace-cross Abstract: Introduction: Semantic search, which retrieves documents based on conceptual similarity rather than keywords, offers advantages for retrieval of clinical information.
By Faith Wavinya Mutinda, Spandana Makeneni, Anna Lin, Shivaji Dutta, Irit R. Rasooly, Patrick Dibussolo, Shivani Kamath Belman, Hessam Shahriari, Kevin Murphy, Alex B. Ruan, Barbara H. Chaiyachati, Sanjay Chainani, Robert W. Grundmeier, Scott M. Haag, Jeffrey M. Miller, Heather M. Griffis, Ian M. Campbell
The paper introduces Diagnostic Loss (DLoss), an objective designed to align radiology report generation with the asymmetric requirement of accurately stating supported diagnoses while avoiding unsupported ones. DLoss operates on decoder token probabilities, aggregating mass over vocabularies for supported and unsupported diagnoses and applying asymmetric pooling to encourage correct diagnoses and suppress spurious ones. Applied to various 3D MedVLMs on 50,000 abdominal CT scans, DLoss improves diagnostic faithfulness without compromising conventional language‑generation metrics.
By Ignacy Kolton, Wenxuan Li, Zongwei Zhou, Jaros{\l}aw B. \'Cwik{\l}a, Arkadiusz Sitek, Pedro R. A. S. Bassi, Szymon P{\l}otka
The paper presents a method for extracting key information from OCR‑digitized clinical reports, addressing challenges posed by heterogeneous documents and noisy OCR output. It introduces an open key space that is iteratively mined, normalized, clustered, and verified to build a canonical key inventory, and defines key coverage as a metric for inventory completeness. Experiments on reports from over 20 hospitals using a 0.2B BERT model show that performance improves steadily with key coverage, achieving high F1 scores when the top 90 keys are covered and outperforming a fine‑tuned Qwen3‑0.6B baseline.
By Yu Wang, Yingyun Li, Ying Qin, Haiyang Qian
CRISS is a retrieval‑augmented generation chatbot designed to aid cancer registrars by providing rapid, citation‑supported answers to complex coding and staging questions. It uses a domain‑specific knowledge base of national registry standards, indexed as dense embeddings, to retrieve relevant passages that ground responses generated by a large language model. In evaluations, RAG configurations consistently outperformed non‑RAG baselines across easy, medium, and hard questions, achieving higher grounding and semantic similarity scores while maintaining human oversight for final decisions.
By Vani Seth, Mohammad Beheshti, Anirudh Kambhampati, Vishwa Bhayani, Lucinda Ham, Prasad Calyam, Iris Zachary
The paper introduces a structured approach to extracting skill and responsibility level pairs from free text using the Skills Framework for the Information Age (SFIA). It evaluates five methods—including lexical baselines, retrieval‑augmented generation, and multi‑agent crews—against expert‑mapped European ICT role profiles, finding that generative strategies are more precise and that only explicit level‑prediction strategies reliably assign responsibility levels. The study also releases an automated SFIA‑9 corpus and establishes the first reproducible baseline for level‑aware skill extraction.
By Ranuga Disansa, U. S. Samarasinghe, Lasith Gunawardena
The paper introduces ICD-Deepresearch, a workflow that combines foundation models for electronic health records (EHR) and language models with medical search and ICD dictionaries to forecast future ICD codes for upcoming clinical encounters. It evaluates candidate code transitions by linking patient evidence, external clinical relations, and exact code semantics within a fixed top‑K budget, using SparseEHR for initial priors, GPT‑5 for complementary forecasts, and a final selection step that validates, deduplicates, and ranks candidates. The method achieves patient‑averaged precision/recall of 24.60/35.09% on MIMIC‑III and 25.14/48.32% on MIMIC‑IV, with physicians rating 51–68% of its retrieved documents as useful, outperforming standalone GPT‑5 web search and Medical Deep Research.
By Junda Wang, Meysam Ghaffari, Akshat Choube, Mohsen Sharifi Renani, Hong Yu, Carlos Morato
The paper introduces Clinical System One (CS1), a 4‑billion‑parameter decision model that rapidly produces typed judgments from clinical records. Trained on 12.4 million Q&A pairs from 3.6 million patients, CS1 can answer multiple questions in a single forward pass, providing probability estimates for uncertain cases. In evaluations on 963,408 held‑out patients and 21 external datasets, CS1 outperformed larger open models and, when paired with a language‑model agent, efficiently identified trial‑eligible patients with far fewer tokens.
By Andrew Zhang, Trinh T. L. Vuong, Sophia J. Wagner, Dongmin Bang, Tong Ding, Yuchang Su, Mary Cipperman, Christina S. Chen, Judith Lefkes, Ramin Kahidi, Ming Y. Lu, Caiwei Tian, Tianhao Luo, Jingnan Ma, Rowland Pettit, Long Phi Le, Faisal Mahmood