arXiv AI

Right Choice of Classification Algorithms Based on Reinforcement Learning for Prediction of Non-Alcoholic Fatty Liver

The paper proposes a reinforcement‑learning framework, termed Fourth Degree Learning, that automatically selects the most suitable classification algorithm for disease prediction tasks. Using this method, the authors report a significant improvement in predictive accuracy for Primary Biliary Cirrhosis, raising it from 63% to 98%. The approach relies on a scoring mechanism called square learning (SL) to guide the algorithm selection process.

arXiv Machine Learning
Jun 2

Early Prediction of Liver Cirrhosis Up to Two Years in Advance: A Machine Learning Study Benchmarking Against the FIB-4 and APRI Scores

arXiv:2601. 00175v2 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years prior to diagnosis using routinely collected electronic health record (EHR) data and benchmark their performance against the FIB-4 and APRI clinical scores.

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv Machine Learning
Aug 20

Transforming Heart Disease Prediction with Advanced Machine Learning Techniques

The study evaluates several machine‑learning classifiers for predicting heart disease using two public datasets, each with 14 health‑related attributes. Performance metrics such as MAE, RAE, accuracy, precision, recall, and F‑measure were used, revealing that SVM performed best on the UCI data while Simple Cart excelled on the Kaggle data. The authors conclude that well‑tuned ML models can aid early heart‑disease diagnosis and suggest future work on hybrid methods and newer datasets.

By Sami Ullah, Muhammad Mohsin Khan
arXiv Machine Learning
Sep 30

Does Machine Learning Outperform Traditional Fibrosis Scores in Predicting Liver Cirrhosis Risk? A Longitudinal EHR-Based Study

arXiv:2601.00175v3 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years before diagnosis using...

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv AI
Sep 15

Potential of Artificial Intelligence Algorithms for Identification of Relevant Diagnostic and Prognostic Biomarkers of Early-Stage Liver Cancer

This study investigates deep learning and explainable AI methods to diagnose hepatocellular carcinoma (HCC) and identify diagnostic and prognostic biomarkers across five disease stages using a transcriptomic dataset built via semi‑supervised learning. The best model used 15 genes selected by SelectKBest, achieving 90.74% accuracy, while a 20‑gene model had the lowest loss of 0.3187. SHAP‑based XAI highlighted DNAJB14 as the most influential gene, and functional validation showed that inhibiting DNAJB14 reverses key malignant traits of HCC cells.

By Ali Bou Nassif, Darko Castven, Manar Abu Talib, Jibran Sualeh Muhammad, Ahmed Ammar Kubba, Jens Marquardt, Abdalla Sayed Ali