arXiv Machine Learning

Virtual Patients, Real Gains: Digital Twin-Based Simulated CT for Multitask Lung Nodule Analysis

arXiv:2502. 21187v4 Announce Type: replace Abstract: AI-based lung cancer screening is constrained by scarce, annotated CT data, particularly for rare nodule presentations.

arXiv Machine Learning
Jul 2

Foundation Models vs. Radiomics for Lung Computed Tomography: A Benchmark of Feature Extractors, Classification Heads, and Segmentation Choices

arXiv:2607. 01001v1 Announce Type: cross Abstract: Radiomics is the established approach for CT-based lung cancer phenotyping, yet comparisons with foundation models rarely isolate contributions of feature extractor, classification head, and segmentation choice, or test cross-cohort robustness.

By Nils Neukirch, Martin Maurer, Nils Strodthoff
arXiv AI
Aug 18

FZ-VLM: A Two Stage Florence-Zephyr Vision Language Model Framework for Pulmonary Nodule Characterization and Clinical Decision Making

arXiv:2608. 15004v1 Announce Type: cross Abstract: Lung cancer remains one of the leading causes of cancer-related mortality worldwide, and Computed Tomography (CT) is a primary imaging tool for screening and followup assessment.

By Pramit Dutta, Jenita Manokaran, Richa Mittal, Ryan Appleby, Eranga Ukwatta
arXiv Computer Vision
Aug 31

Prompt-Guided Interactive Segmentation of Interstitial Lung Disease in Thoracic CT

The paper introduces the first adaptation of the MedSAM2 foundation model for interactive 3D segmentation of interstitial lung disease (ILD) on thoracic CT scans. It evaluates three fine‑tuning strategies and four prompt types—bounding‑boxes, points, lassos, and scribbles—finding that full model fine‑tuning yields the best performance, improving Dice scores by 4.7 percentage points over the baseline. A proof‑of‑concept workflow is presented where MedSAM2 is first initialized with an automatic prior and then refined by radiologist prompts, with all resources released on GitHub.

By Vasilis Dedousis, Lubnaa Abdur Rahman, Lorenzo Brigat{\omicron}, Ethan Dack, Andreas Christe, Christoph Frank, Manuela Funke-Chambour, Justus Roos, Adrian Huber, Lukas Ebner, Stavroula Mougiakakou
arXiv AI
Aug 28

A Comprehensive Comparison of Deep Learning Architectures for COVID-19 Classification on CT & X-ray Imagery

The article presents a comparative study of convolutional neural network (CNN) architectures for classifying COVID-19 from healthy lung images using CT and X‑ray scans. Multiple pre‑trained models—including VGG, DenseNet, ResNet, MobileNet, Xception, Inception, EfficientNet, and NasNet—were evaluated on two X‑ray and two CT datasets. ResNet and VGG achieved the highest accuracies, ranging from 95% to 98%, outperforming previous reports in the literature.

By Sarmad Khan, Basim Azam, Arslan Shaukat
arXiv Computer Vision
Aug 25

Extending the Horizon of Early Diagnosis: Lung Cancer Prediction with Vision Transformers

arXiv:2608.21571v1 Announce Type: new Abstract: Lung cancer remains a leading cause of cancer-related mortality worldwide, and early diagnosis is critical for improving survival. However, early-stage...

By Olivera Kotevska, Ian Goethert, Michael McGee, Maria Mahbub, Sean R. Wilkinson, Rowena Yip, Myvizhi Esai Selvan, Zeynep H. Gumus, Claudia Henschke, Robert J. Klein, Providencia Morales, Samuel M Aguayo, Ioana Danciu, Mayanka Chandrashekar
arXiv AI
Jun 8

When is 3D Worth It? A Resource-Performance Frontier for CNNs and Transformers in Lung CT

arXiv:2606. 06950v1 Announce Type: cross Abstract: Three-dimensional models are widely assumed preferable for volumetric medical imaging, yet their practical value depends on whether performance gains justify added computational cost and complexity.

By Md Enamul Hoq, Sharafat Hossain, Imraul Emmaka, Linda Larson-Prior, Lawrence Tarbox, Jonathan Bona, Donald Johann Jr. and Fred Prior
arXiv AI
Jun 2

RadAgent: A tool-using AI agent for stepwise interpretation of chest computed tomography

arXiv:2604. 15231v2 Announce Type: replace Abstract: Vision-language models (VLM) have markedly advanced AI-driven interpretation and reporting of complex medical imaging, such as computed tomography (CT).

By M\'elanie Roschewitz, Kenneth Styppa, Yitian Tao, Jiwoong Sohn, Jean-Benoit Delbrouck, Benjamin Gundersen, Nicolas Deperrois, Christian Bluethgen, Julia E. Vogt, Bjoern Menze, Farhad Nooralahzadeh, Michael Krauthammer, Michael Moor
arXiv Machine Learning
Jun 16

A Multi-Center Benchmark for Abdominal Disease Diagnosis and Report Generation from Non-Contrast CT

arXiv:2606. 16991v1 Announce Type: cross Abstract: Multiphasic contrast-enhanced CT (CECT) is widely used for abdominal lesion characterization, yet it carries inherent risks of contrast-induced nephropathy, escalates acquisition burden, and heavily contributes to radiologist workload.

By Mariam Elbakry, Aliaa Sayed Sheha, Salma Hassan Tantawy, Aya Yassin, Concetto Spampinato, Karim Lekadir, Xiaomeng Li, Marawan Elbatel