The study explores how adding anatomical priors and active learning can improve the accuracy of deep learning models for segmenting the Clinical Target Volume (CTV) in gastric cancer radiotherapy. Using 100 retrospective CT scans, an nnU‑Net model trained on 10 expert‑contoured cases was enhanced with voxel‑wise anatomical prior maps and iterative active learning over four rounds. The combined approach raised the mean Dice Similarity Coefficient from 0.84 to 0.87, demonstrating that both techniques individually and together improve segmentation performance and generalizability.
By Phillip Chlap, Mark Lee, Trevor Leong, Matthew Field, Jason Dowling, Hang Min, Julie Chu, Jennifer Tan, Phillip K. Tran, Tomas Kron, Annette Haworth, Martin A. Ebert, Shalini K. Vinod, Lois Holloway
Foundation models such as Segment Anything Model 2 (SAM2) have transformed natural-image and video segmentation, and recent work has begun adapting them to medical imaging. These adaptations, however, are largely general-purpose models that treat MRI as one modality among many; large-scale, MRI-specific modelling and benchmarking remain limited, even though MRI's low soft-tissue contrast leaves many boundaries effectively invisible on individual slices.
arXiv:2609.37648v1 Announce Type: new
Abstract: Preoperative liver-tumor assessment requires segmentation, physical-space measurement, visual evidence, and resection planning from the same three-dime...
By Binghong Qian, Xuanhe Liu, Yifan Xing, Wenjie Deng, Jian Wu, Haochao Ying
The paper introduces the first adaptation of the MedSAM2 foundation model for interactive 3D segmentation of interstitial lung disease (ILD) on thoracic CT scans. It evaluates three fine‑tuning strategies and four prompt types—bounding‑boxes, points, lassos, and scribbles—finding that full model fine‑tuning yields the best performance, improving Dice scores by 4.7 percentage points over the baseline. A proof‑of‑concept workflow is presented where MedSAM2 is first initialized with an automatic prior and then refined by radiologist prompts, with all resources released on GitHub.
By Vasilis Dedousis, Lubnaa Abdur Rahman, Lorenzo Brigat{\omicron}, Ethan Dack, Andreas Christe, Christoph Frank, Manuela Funke-Chambour, Justus Roos, Adrian Huber, Lukas Ebner, Stavroula Mougiakakou
DALE-CT introduces depth‑aware 2D slice encoders that learn an anatomical world model of chest CT scans without 3D or positional supervision. By sampling self‑supervised views across a physical $z$‑axis slab, the encoder captures how anatomy changes between neighboring slices, enabling it to recover slice ordering and distinguish slices by anatomy alone. The model, trained on a large 287k‑scan corpus, achieves state‑of‑the‑art performance on CT‑RATE and is released with full code and evaluation tools.
By Evan W. Damron, Mahmut S. Gokmen, Mitchell A. Klusty, Caroline N. Leach, Emily B. Collier, V. K. Cody Bumgardner
In clinical oncology studies, metastatic cancer is commonly evaluated using "Response Evaluation Criteria in Solid Tumors" (RECIST), in which the diameter of up to five lesions is measured and followed over the course of treatment. However, RECIST shows limited correlation with overall survival.
arXiv:2608.28455v1 Announce Type: new
Abstract: Contrastive vision-language learning uses paired chest CT volumes and radiology reports to learn abnormality classifiers without manually annotated lab...
By Huseyin Umut Isik, Mehmet Alp Ozaydin, Sila Kurugol, \c{S}eyda Ertekin
BrainIAC is a unified framework for 3D brain lesion segmentation that handles heterogeneous MRI modalities and adapts online during interactive segmentation. It combines a multi‑modal backbone trained with zero‑filling and random modality dropping, 3D interactive prompts that default to fully automatic predictions, and a two‑stage online adaptation guided by pseudo‑labels and a Click‑Centered Gaussian loss. Experiments on seven MRI datasets show that the components work synergistically, outperforming existing methods and generalizing to unseen modalities and pathologies.
By Wentian Xu, Anthony P Addison, Ziyun Liang, Harry Anthony, Guang Yang, Konstantinos Kamnitsas
The study investigates how few expert-annotated cases are needed to fine‑tune MedSAM3 for abdominal organ segmentation using Low‑Rank Adaptation (LoRA). With only 10 annotated CT or MRI cases, the LoRA‑adapted models achieve performance comparable to specialist systems that require orders of magnitude more data, including reliable gallbladder segmentation and near‑state‑of‑the‑art results for liver, kidneys, and spleen. The approach also generalizes to cardiac segmentation on the Whole Heart dataset, and training takes only 3–5 hours per organ on a single GPU, roughly twice as fast as nnU-Net.
By Sachin Dudda Nagaraju, Bendik Skarre Abrahamsen, Ashkan Moradi, Mattijs Elschot
arXiv:2608.30844v1 Announce Type: cross
Abstract: Interactive lesion segmentation in whole-body PET/CT requires a model to provide a strong initial prediction while also responding efficiently to spa...
By Xinglong Liang, Chunyao Lu, Tianyu Zhang, Jiaju Huang, Tao Tan, Yunchao Yin, Lishan Cai
arXiv:2604.27697v2 Announce Type: replace-cross
Abstract: Peritoneal metastases (PM) are staged using the surgically determined Peritoneal Cancer Index (sPCI), which requires invasive laparoscopic as...
By Pieter C. Gort, Lotte J. S. Fleurkens-Ewals, Lenah D. Kampmeijer, Anna F. van Herwijnen, Marion W. Tops-Welten, Cris H. B. Claessens, Joost Nederend, Ignace H. J. T. De Hingh, Max J. Lahaye, Misha D. P. Luyer, Fons van der Sommen
arXiv:2609.16775v1 Announce Type: new
Abstract: Annotating large radiology datasets is bottlenecked by the manual effort of delineating structures slice-by-slice in 3D volumes. Interactive methods re...
By Abhilaksh Singh Reen, Kushal Borkar, Ritvik Mahapatra