arXiv AI

Meta-CLIP: Metadata-Conditioned Contrastive Learning for Zero-Shot Disease Inference

Meta-CLIP is a metadata‑conditioned contrastive learning framework that incorporates DICOM acquisition information to reweight cross‑modal negatives during medical vision‑language pretraining. By defining a bounded pairwise margin over numerical and categorical DICOM fields, the method emphasizes distinctions among studies with similar imaging conditions while keeping the kernel fixed during optimization. Evaluations on chest radiography and volumetric CT show that Meta‑CLIP improves zero‑shot classification performance, achieving higher macro‑AUROC scores than baseline CLIP models on multiple benchmarks.

arXiv AI
Sep 25

Med-AR: Autoregressive Vision-Language Pretraining for Long-Tailed Chest X-Ray Classification and Uncertainty-Aware Evaluation

Med-AR introduces two autoregressive vision‑language models, Med‑AR‑8B and Med‑AR‑2B, pretrained on structured radiology reports, abnormality‑focused text, and region annotations to address long‑tailed chest X‑ray classification. The models outperform existing contrastive, self‑supervised, and supervised encoders—including Med‑CLIP, CheXFound, EVA‑Base, ARK, and BioViL‑T—across PadChest, MIMIC‑CXR, and CheXpert, achieving higher mean AUROC and AUPRC for head, medium, and tail findings and lower excess area under the risk‑coverage curve. Med‑AR also demonstrates improved selective‑prediction performance, with Med‑AR‑8B raising tail‑label mean AUPRC on MIMIC‑CXR from 0.1033 to 0.1441 and Med‑AR‑2B delivering the strongest discrimination on PadChest.

By Janhavi Prabhu, Sahil, Akshay V, Shivam Shukla, Manoj Tadepalli, Preetham Putha
arXiv Computer Vision
Aug 26

Example-based Robust Abnormality Detection with Minimal Annotations using Exemplar Med-DETR

arXiv:2608.24281v1 Announce Type: new Abstract: Reducing annotation requirements remains a key challenge in developing robust medical object detectors. To address this, Vision-Language (VL) object de...

By Sheethal Bhat, Bogdan Georgescu, Awais Mansoor, Mathias Zinnen, Pranjal Sahu, Florin C. Ghesu, Sasa Grbic, Andreas Maier
arXiv Computer Vision
Oct 16

SCCL-DT: Semantic-Conflict-Aware Contrastive Learning with Dual-Rule Teacher Distillation for Zero-Shot Chest X-Ray Diagnosis

The paper introduces SCCL-DT, a method that improves zero‑shot chest X‑ray diagnosis by addressing semantic conflicts in contrastive vision‑language pre‑training. It uses adaptive thresholds derived from exponential‑moving‑average statistics to hard‑mask conflicting pairs, and combines two teachers—an inclusive and a consensus rule—through distillation into a single student model. On five public chest X‑ray benchmarks, SCCL‑DT achieves a mean zero‑shot AUC of 0.850, outperforming the best baseline at 0.837.

By Ting Liu, Haoran Lai, HaobinChen, Ming Liu, S Kevin Zhou
arXiv Machine Learning
Aug 18

Comprehensive language-image pre-training for 3D medical image understanding

arXiv:2510. 15042v3 Announce Type: replace-cross Abstract: In the 3D medical image domain, vision-language pre-training is used to create vision-language encoders (VLEs) that can support radiologists by retrieving patients with similar abnormalities, predicting likelihoods of abnormality, or, with downstream adaptation, generating radiological reports.

By Tassilo Wald, Ibrahim Ethem Hamamci, Yuan Gao, Sam Bond-Taylor, Harshita Sharma, Maximilian Ilse, Cynthia Lo, Olesya Melnichenko, Anton Schwaighofer, Noel C. F. Codella, Maria Teodora Wetscherek, Klaus H. Maier-Hein, Panagiotis Korfiatis, Valentina Salvatelli, Javier Alvarez-Valle, Fernando P\'erez-Garc\'ia
Hugging Face Trending Papers
Jun 24

Disease-Centric Vision-Language Pretraining with Hybrid Visual Encoding for 3D Computed Tomography

Vision-language pre-training (VLP) holds great promise for general-purpose medical AI by leveraging radiology reports as rich textual supervision, yet existing methods struggle with 3D CT imaging due to inefficient visual backbones and coarse semantic alignment. To address these issues, we propose a tailored VLP framework featuring three key components: (1) a CNN-ViT hybrid encoder that replaces ViT's patch embedding with a 3D CNN backbone to efficiently capture local anatomical details while preserving global attention and compatibility with pre-trained cross-modal priors; (2) a disease-level contrastive learning mechanism using learnable query tokens to dynamically extract disease-specific semantics from full reports and align them with corresponding visual features, thereby disentangling distinct diseases within the same anatomical region; and (3) a diagnosis-aware prompt strategy that employs real clinical phrases and aggregated disease prototypes to bridge the pre-training-inference gap and enhance zero-shot diagnostic reliability.

arXiv Computer Vision
Oct 22

Expandable Modality Experts for Medical Vision-Language Learning

The paper introduces Expandable Modality Experts, a medical vision‑language framework that uses an expandable bank of modality experts and a Multiway Transformer to combine shared visual computation with deterministic routing and a separate text pathway. It employs a modality‑aware visual tokenizer for masked pretraining on 19.4 million unpaired image rows across seven modalities, followed by contrastive alignment on 3.23 million image‑text pairs. With a ViT‑Large backbone, the method achieves state‑of‑the‑art results in 24 of 25 benchmark settings across nine modalities, including zero‑shot classification, linear probing, and retrieval tasks, while preserving existing representations.

By DM BAPPY, Eunsu Kim, Hanjoo Lee, Sung Hak Lee, Sangjeong Ahn
arXiv Computer Vision
Aug 25

Expert-level vision-language foundation model for real-world radiology and comprehensive evaluation

arXiv:2409.16183v2 Announce Type: replace Abstract: Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in m...

By Xiaohong Liu, Guoxing Yang, Yulin Luo, Jiaji Mao, Xiang Zhang, Haibo Wang, Zhiyang He, Ming Gao, Shanghang Zhang, Jun Shen, Guangyu Wang
arXiv Machine Learning
Jun 3

GLINT: Sparsely Gated Vision-Language Alignment for Fine-Grained Radiology Representations

arXiv:2606. 03180v1 Announce Type: cross Abstract: Vision-language models (VLMs) for radiology have emerged as a scalable paradigm by leveraging image-report pairs naturally produced in clinical workflows.

By Jonggwon Park, Seongeun Lee, Junhyun Park, Hannah Yun, Hyunwoong Kim, Sohyun Jeong, Hyewon Kang, Byungmu Yoon, Kyoyun Choi
arXiv AI
Aug 5

CARE-X: Towards Clinically Useful Radiology VLMs with Auxiliary Supervision, Reward-Aligned Learning, and Tool-Augmented Measurement

arXiv:2608. 03890v1 Announce Type: cross Abstract: A clinically useful chest X-ray system must go beyond fluent report generation: it should classify findings with tunable decision thresholds, localize them spatially, and derive the anatomical measurements upon which many diagnoses depend.

By Mercy Prasanna Ranjit, Anirban Porya, Sathvik Joel, Niharika Vadlamudi, Nikhilesh Chowdary Eathamukkala, Prasanth V V, Abhyuday Kumara Swamy, Pranay Narhari Umredkar, Pradeep Narayan, Vivek Rajagopal, Tanuja Ganu