arXiv:2606. 05797v1 Announce Type: new Abstract: Longitudinal treatment decisions require predicting potential outcomes under future treatment sequences in the presence of time-varying confounding, heterogeneous patient dynamics, and limited domain-specific data.
Many clinical prediction models treat post-intervention outcomes as a one-step mapping from baseline measurements to a future endpoint. However, recovery after a procedure often unfolds as an irregular trajectory: clinical observations, medication changes, repeat interventions, and physiological measurements are recorded asynchronously and can change risk assessment over time.
Structural causal models are the standard language for reasoning about interventions and counterfactuals, but they describe static variables, typically measured once, and usually forbid cyclic dependencies. Many systems we care about, such as patients, climates, and economies, instead evolve continuously in time, are observed at irregular time points, and contain feedback loops.
arXiv:2512. 08029v3 Announce Type: replace Abstract: Clinical decision-making in oncology requires predicting dynamic disease evolution, a task current static AI predictors cannot perform.
arXiv:2611.08077v1 Announce Type: cross Abstract: We propose a doubly-robust method to estimate the causal effects of multi-valued treatment regimes on patient outcomes. A multi-valued treatment regi...
arXiv:2609.36144v1 Announce Type: new Abstract: Electronic health records provide irregular observations of latent patient states that evolve continuously over time. Recent autoregressive models cond...
arXiv:2606. 30398v1 Announce Type: new Abstract: Accurately predicting the temporal evolution of clinical biomarkers is crucial for the early diagnosis and management of neurodegenerative diseases such as Alzheimer's disease.
The paper introduces PICLE-PFN, a foundation model for longitudinal causal effect estimation that handles dynamic treatment policies. It represents policies via in-context history-decision demonstrations and is pretrained on synthetic data from longitudinal structural causal models, enabling it to predict conditional average potential outcomes in a single forward pass without task-specific training. Experiments on synthetic and semi-synthetic benchmarks show competitive RMSE and better uncertainty calibration while reducing deployment runtime compared to conventional estimators.
The paper tackles the problem of estimating causal effects when an unobserved confounder is present. It assumes a single, possibly multi‑dimensional proxy variable for the confounder and knowledge of the mechanism that generates this proxy. Under the Single Proxy Identifiability of Causal Effects (SPICE) assumption, the authors prove that the error mechanism is complete and causal effects are identifiable, extending prior proxy‑based results to continuous, multi‑dimensional settings and more flexible functional forms. They also introduce SPICE‑Net, a neural‑network‑based framework for estimating causal effects applicable to both discrete and continuous treatments.
arXiv:2606. 18049v1 Announce Type: new Abstract: Decision-making with deep learning-based time series forecasting requires not only accurate predictions but also actionable insights.
arXiv:2607. 27263v1 Announce Type: new Abstract: Most benchmarks for causal inference over time series are observational, small, or domain-specific, leaving interventional and counterfactual estimation under-served exactly where it matters most, such as in healthcare, policy evaluation, and climate science.
arXiv:2608. 13518v1 Announce Type: new Abstract: Many clinical prediction models treat post-intervention outcomes as a one-step mapping from baseline measurements to a future endpoint.