arXiv AI

CARE-MH: Towards Unified, Reproducible, and Comparable Evaluation of Mental Health LLMs

arXiv:2607. 24754v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly used to provide mental health support, requiring reliable evaluation of safety, empathy, and therapeutic appropriateness.

arXiv AI
Sep 15

A primer on evaluation methods for large language models in healthcare

arXiv:2609.14819v1 Announce Type: cross Abstract: Large language models (LLMs) have a growing range of applications in medicine, and their evaluation is critical for ensuring they provide benefit and...

By Suzannah E McKinney, Phuc Vu, Samuel A Justice, Christopher Humphries, Alyssa Pradhan, Timothy J Keyes, Bernardo C Bizzo, Keith J Dreyer, Sarah F Mercaldo, James M Hillis
arXiv Computation and Language
Aug 31

Roleplaying with Structure: Synthetic Therapist-Client Conversation Generation from Questionnaires

arXiv:2510.25384v2 Announce Type: replace Abstract: Large Language Models (LLMs) are promising tools for synthetic data generation in mental health. However, privacy policies and restrictions forced...

By Doan Nam Long Vu, Rui Tan, Lena Moench, Svenja Jule Francke, Daniel Woiwod, Florian Thomas-Odenthal, Sanna Stroth, Tilo Kircher, Christiane Hermann, Udo Dannlowski, Hamidreza Jamalabadi, Simone Balloccu, Shaoxiong Ji
arXiv AI
Jul 10

MentalHospital: A Virtual Environment for Evaluating Psychiatric Clinical Encounters

arXiv:2607. 08257v1 Announce Type: new Abstract: Large language models (LLMs) have shown strong performance on isolated psychiatric tasks, including dialogue, diagnosis, and treatment planning, yet existing benchmarks rarely simulate complete psychiatric clinical encounters.

By Yuming Yang, Xiao Sun, Yuanwei Zou, Zhengxiao Wu, Yun Chen, Jiang Zhong, Haoyang Zeng, Jingwang Huang, Kaiwen Wei
arXiv AI
Jul 1

Training Therapeutic Judges and Multi-Agent Systems for Human-Aligned Mental Health Support

arXiv:2606. 30887v1 Announce Type: cross Abstract: Large language models show promise for mental health support, yet therapeutic quality improves only when evaluation functions as an actionable control signal rather than a passive metric.

By Mizanur Rahman, Abeer Badawi, Elahe Rahimi, Laleh Seyyed-Kalantari, Frank Rudzicz, Enamul Hoque, Elham Dolatabadi
arXiv AI
Sep 15

K-Bench: a clinically calibrated benchmark for evaluating large language models in high-risk mental health conversations

arXiv:2609.15855v1 Announce Type: cross Abstract: % !TEX root = ../main.tex People increasingly use large language models (LLMs) for mental health support, yet their safety in evolving, high-risk con...

By Laura M. Vowels, Matthew J. Vowels, Shivali Sharma, Apoorv Jha, Rehnuma Choudhury, Wasseem El Sarraj, Rachel Francois-Walcott, Aruba Hussain, Sarah Ingram, Angela Loulopoulou, Adva Segal, Elena Volkova
arXiv AI
Jul 16

Ask Before You Diagnose: Safe-Psych, a Sequential Evaluation Benchmark for LLMs in Psychiatry

arXiv:2607. 13036v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly used for decision support in healthcare, but clinical evidence is often incomplete or evolving.

By Oriana Presacan, Andreea Grama, Larisa Irimin\u{a}, Alireza Nik, Jaya Ojha, Vajira Thambawita, Ciprian I. B\u{a}cil\u{a}, Bogdan Ionescu, Michael A. Riegler
arXiv Computation and Language
Sep 22

LLJ Cards: Best practices for the Use of LLMs as Judges

arXiv:2609.24516v1 Announce Type: new Abstract: In recent years, large language models (LLMs) have emerged as a popular alternative for evaluation. Often referred to as LLMs as judges (LLJs), these s...

By Khaoula Chehbouni, Melina Medjdoub, Florian Carichon, Golnoosh Farnadi, Jackie Chi Kit Cheung
arXiv AI
Aug 20

Large Language Models in Mental Health: A Systematic Review of Applications, Innovations, and Ethical Challenges

The paper reviews how large language models are applied in mental health, covering areas such as social media analysis, clinical conversational agents, therapy support tools, prompt engineering, and multimodal learning. It synthesizes interdisciplinary studies that use social media posts, electronic medical records, and multimodal inputs to detect depression, assess suicide risk, provide personalized therapy, and generate psychoeducational content. The review also discusses advances in model interpretability, annotation strategies, multimodal fusion techniques, and highlights ethical, sociotechnical, and regulatory challenges while proposing frameworks for safe, equitable, and accountable deployment.

By Yisong Chen, Yifan Gao, Sijing Yu, Chuqing Zhao, Yang Lu
arXiv Machine Learning
Jul 17

Addressing Benchmarking Gaps in Large Language Models for Health and Medicine with Dynamic Red-Teaming

arXiv:2508. 00923v3 Announce Type: replace Abstract: Large language models (LLMs) are increasingly used to answer health-related questions and support healthcare workflows, yet evidence for their safety still relies heavily on static benchmarks that can rapidly become obsolete or be optimized against.

By Jiazhen Pan (Cherise), Bailiang Jian (Cherise), Paul Hager (Cherise), Yundi Zhang (Cherise), Che Liu (Cherise), Friederike Jungmann (Cherise), Hongwei Bran Li (Cherise), Julian Canisius (Cherise), Chenyu You (Cherise), Junde Wu (Cherise), Jiayuan Zhu (Cherise), Fenglin Liu (Cherise), Yuyuan Liu (Cherise), Niklas Bubeck (Cherise), Moritz Knolle (Cherise), Chen (Cherise), Chen (Cherise), Christian Wachinger, Zhenyu Gong, Cheng Ouyang, Georgios Kaissis, Benedikt Wiestler, Daniel Rueckert
arXiv Computation and Language
Sep 23

From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Health

The article surveys how large language models (LLMs) are being applied to mental health, outlining a three‑phase evolution: Phase I uses LLMs as passive information tools and pattern recognizers for assessment; Phase II employs them as empathetic conversationalists for stateless, in‑the‑moment interactions; Phase III aims to create longitudinal, personalized companions that act as stateful cognitive agents. It systematically reviews core technologies, agent architectures (Profile, Memory, Reasoning, Planning), and the datasets and benchmarks that support this progression, offering a coherent narrative and roadmap for future research. The survey also provides a curated resource list at https://github.com/Emo-gml/Awesome-Mental-Health-LLMs.

By He Hu, Yucheng Zhou, Qianning Wang, Yingjian Zou, Chiyuan Ma, Juzheng Si, Jianzhuang Liu, Zitong Yu, Laizhong Cui, Fei Ma, Qi Tian