arXiv AI

Training Therapeutic Judges and Multi-Agent Systems for Human-Aligned Mental Health Support

arXiv:2606. 30887v1 Announce Type: cross Abstract: Large language models show promise for mental health support, yet therapeutic quality improves only when evaluation functions as an actionable control signal rather than a passive metric.

arXiv AI
Jul 10

MentalHospital: A Virtual Environment for Evaluating Psychiatric Clinical Encounters

arXiv:2607. 08257v1 Announce Type: new Abstract: Large language models (LLMs) have shown strong performance on isolated psychiatric tasks, including dialogue, diagnosis, and treatment planning, yet existing benchmarks rarely simulate complete psychiatric clinical encounters.

By Yuming Yang, Xiao Sun, Yuanwei Zou, Zhengxiao Wu, Yun Chen, Jiang Zhong, Haoyang Zeng, Jingwang Huang, Kaiwen Wei
arXiv Computation and Language
Aug 27

Retrieval-Augmented Agentic Rubric Generation for Reliable Medical Response Evaluation

The paper introduces a retrieval‑augmented multi‑agent framework that automatically generates instance‑specific evaluation rubrics for medical language models. By retrieving authoritative medical evidence, decomposing it into atomic facts, and combining these with user interaction constraints, the system produces fine‑grained criteria that outperform GPT‑4o on HealthBench and LLMEval‑Med. The generated rubrics also guide response refinement, improving medical LLM output quality by 9.2%.

By Yinzhu Chen, Abdine Maiga, Hossein A. Rahmani, Emine Yilmaz
arXiv Machine Learning
Aug 24

Designing a Robust LLM-Based Evaluation System for Agentic AI in Drug Discovery Through Human Alignment

The paper introduces an LLM-as-a-Judge framework for evaluating the outputs of an agentic drug discovery assistant, ChatInvent, deployed at AstraZeneca. It defines four quality dimensions—Completeness, Relevancy, Structural Clarity, and Scope Adherence—alongside deterministic Tool Call Correctness checks, and validates the judge against five expert annotators. After optimizing the best-performing judge with few-shot demonstrations, alignment with human majority votes improves from 0.80 to 0.86, and the framework reveals that informal question phrasing does not degrade output quality.

By Emma Granqvist, Roc\'io Mercado, Samuel Genheden
arXiv Computation and Language
Sep 1

Graph2Counsel: Clinically Grounded Synthetic Counseling Dialogue Generation from Client Psychological Graphs

Graph2Counsel is a framework that generates synthetic counseling dialogues by leveraging Client Psychological Graphs (CPGs) to encode the relationships among a client’s thoughts, emotions, and behaviors. The system uses a structured prompting pipeline guided by counselor strategies and explores techniques such as Chain‑of‑Thought and Multi‑Agent Feedback to produce 760 realistic sessions from 76 CPGs. Expert evaluation shows the dataset surpasses previous ones in specificity, counselor competence, authenticity, conversational flow, and safety, and fine‑tuning an open‑source model on it improves performance on several counseling benchmarks.

By Aishik Mandal, Hiba Arnaout, Clarissa W. Ong, Juliet Bockhorst, Kate Sheehan, Rachael Moldow, Tanmoy Chakraborty, Iryna Gurevych
arXiv AI
Jul 28

OpenAIs HealthBench in Action: Evaluating an LLM-Based Medical Assistant on Realistic Clinical Queries

arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.

By Sandhanakrishnan Ravichandran, Shivesh Kumar, Rogerio Corga Da Silva, Miguel Romano, Reinhard Berkels, Michiel van der Heijden, Olivier Fail, Valentine Emmanuel Gnanapragasam
arXiv AI
Jul 29

PatientAgentBench: A Benchmark Framework for Evaluating Patient-Facing Health AI Agents

arXiv:2607. 25485v1 Announce Type: new Abstract: Health AI is evolving from answering questions to agentic systems that converse with patients, reason about health records, and act on their behalf.

By Korosh Vatanparvar, Ashutosh Joshi, Maria Xenochristou, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Daniel Lopez-Martinez, Anchal Nema, Ramya Ganesan, Will Kimbrough, Alex Woody, Yadunandana Rao, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
arXiv AI
Aug 24

When Vocabulary Comprehension Fails Clinical Reasoning: Evaluating Therapy Bots' Safety Risks for Generation Alpha

The paper evaluates the safety of conversational AI therapy bots for Generation Alpha, revealing that while these models understand 76‑82% of youth‑specific vocabulary, they correctly assess clinical risk only 64‑72% of the time, creating a significant vocabulary‑comprehension gap. Six failure patterns—such as sarcasm masking, minimization acceptance, and semantic drift—were identified, with compounded errors leading to a 94% miss rate when three or more patterns co‑occur. The authors estimate 146,880 missed crises annually and recommend mandatory human‑in‑the‑loop systems, quarterly youth‑specific validation, transparent performance disclosure, and regulatory oversight for youth‑facing mental health AI.

By Manisha Mehta, Virendra Mehta