Environment-Robust Representation Learning with Empirical Bayes
arXiv:2606. 05365v1 Announce Type: cross Abstract: We consider multi-environment prediction problems.
This paper introduces a hierarchical Bayesian multitask learning model that assumes a shared sparsity structure across different binary classification tasks. The authors develop a variational inference algorithm for efficient posterior approximation and evaluate the method on synthetic data and pooled microbiome studies. Results show superior support recovery in synthetic experiments and robust, well‑calibrated predictions with informative taxa selection in microbiome classification.
arXiv:2606. 05365v1 Announce Type: cross Abstract: We consider multi-environment prediction problems.
arXiv:2607. 02103v1 Announce Type: cross Abstract: Classifying heterogeneous omics data remains a fundamental challenge in computational biology, particularly in high-dimensional, small-sample settings where nonlinear interactions dominate and class imbalance further complicates reliable prediction of minority phenotypes.
arXiv:2606. 20538v1 Announce Type: new Abstract: Bayesian predictive inference provides a principled framework for uncertainty quantification, data efficiency, and robust generalization.
arXiv:2608. 08182v1 Announce Type: cross Abstract: Machine learning models for MALDI-TOF mass spectrometry have shown considerable promise for clinical microbiology tasks such as microbial identification and antimicrobial resistance prediction.
arXiv:2605. 29058v2 Announce Type: replace Abstract: Bayesian Networks (BNs) are of interest from an explainable AI viewpoint, offering transparent probabilistic models for decision support.
arXiv:2509. 00123v2 Announce Type: replace-cross Abstract: A fundamental challenge in microbial ecology is determining whether bacteria compete or cooperate in different environmental conditions.
Antimicrobial peptides (AMPs) often act against multiple pathogen classes, making multi-label activity prediction a more realistic screening target than binary antimicrobial classification. The ESCAPE...
arXiv:2607. 00995v1 Announce Type: cross Abstract: Most existing multitask learning approaches are limited by their reliance on task-specific loss functions tailored to the scale and type of each outcome.
arXiv:2605. 31014v2 Announce Type: replace Abstract: Multi-omics data provide complementary molecular characterizations of disease phenotypes and play an important role in disease diagnosis and subtype classification in precision medicine.
The study demonstrates that a simple, sequence-only approach using 330 interpretable descriptors and the TabPFN tabular foundation model can outperform complex multimodal deep learning methods for multi-label antimicrobial peptide activity prediction. On the ESCAPE benchmark (82,359 peptides, five labels), a label‑powerset TabPFN model achieved a mean average precision of 77.8%, surpassing the previous best of 72.1%. The approach also shows that predicted structure is unnecessary, that a small set of global physicochemical scalars can recover most performance, and that modeling label dependence benefits rare activities and informs assay prioritization.
arXiv:2607. 27023v1 Announce Type: new Abstract: Evaluating large generative models across benchmarks is time-consuming and computationally expensive.
arXiv:2606. 02228v1 Announce Type: cross Abstract: Predicting whether an individual with Alzheimer's disease will experience mild or severe disease progression is essential for personalized treatment.