arXiv:2606. 28332v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly used for medical and health-related questions, yet their safety in high-risk medical scenarios remains poorly understood.
arXiv:2601. 17642v2 Announce Type: replace Abstract: Safety alignment in Large Language Models is critical for healthcare; however, reliance on binary refusal boundaries often results in over-refusal of benign queries or unsafe compliance with harmful ones.
arXiv:2602.06268v2 Announce Type: replace-cross Abstract: Large Language Models (LLMs) and Retrieval-Augmented Generation (RAG) systems are increasingly integrated into clinical workflows. However, p...
arXiv:2607. 18665v1 Announce Type: new Abstract: Large language models (LLMs) increasingly support science, but they can also convert hazardous scientific knowledge into actionable misuse guidance.
The paper introduces HarmReduction, a benchmark for evaluating large language models (LLMs) on their ability to provide accurate and safe harm reduction information to people who use drugs (PWUD). The benchmark, HR-Basic, contains 2,160 question‑answer‑evidence pairs covering safety boundary checks, quantitative value provision, and polysubstance risk inference. Experiments show that even state‑of‑the‑art LLMs struggle with accuracy and can pose severe safety risks, underscoring the need for a dedicated evaluation framework.
arXiv:2606. 07237v1 Announce Type: cross Abstract: Large Language Models (LLMs) are increasingly used in healthcare for tasks such as clinical question answering, diagnosis support, and report summarization.
arXiv:2508. 00923v3 Announce Type: replace Abstract: Large language models (LLMs) are increasingly used to answer health-related questions and support healthcare workflows, yet evidence for their safety still relies heavily on static benchmarks that can rapidly become obsolete or be optimized against.
arXiv:2608. 03028v1 Announce Type: new Abstract: Applying a valid medication-safety rule when its patient-specific conditions are not met can produce an incorrect decision.
Large language models (LLMs) increasingly support science, but they can also convert hazardous scientific knowledge into actionable misuse guidance. Existing benchmarks often rely on templated queries disconnected from real-world hazards, and employ LLM-as-a-Judge paradigms without domain grounding.
arXiv:2409. 07314v3 Announce Type: replace-cross Abstract: While Large Language Models (LLMs) achieve superhuman performance on standardized medical licensing exams, these static benchmarks have become saturated and increasingly disconnected from the functional requirements of clinical workflows.
arXiv:2507. 02983v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) hold significant promise for transforming digital health by enabling automated medical question answering.
SafeTune is a source‑available library that consolidates four safety‑intervention paradigms—post‑hoc weight recovery, safety‑constrained fine‑tuning, gradient‑based unlearning, and inference‑time steering—into a single, configuration‑driven workflow. It offers shared interpretability, evaluation, and deployment tools, and its modular registry allows easy addition of new methods, benchmarks, judges, models, and fine‑tuning domains. The authors demonstrate SafeTune with controlled comparisons and case studies in finance and medical deployments, showing how it characterizes safety drift, evaluates interventions on refusal‑behavior and capability metrics, and supports calibrated or layered mitigation.
arXiv:2512. 01241v3 Announce Type: replace-cross Abstract: Large language models (LLMs) are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized.