Large language models (LLMs) increasingly support science, but they can also convert hazardous scientific knowledge into actionable misuse guidance. Existing benchmarks often rely on templated queries disconnected from real-world hazards, and employ LLM-as-a-Judge paradigms without domain grounding.
arXiv:2606. 18936v1 Announce Type: new Abstract: Large language models (LLMs) are increasingly embedded in AI for Science (AI4Science) workflows, from scientific question answering and literature analysis to laboratory planning and autonomous discovery.
By Linghao Feng, Yinqian Sun, Dongqi Liang, Sicheng Shen, Chenfei Yan, Yuxuan Peng, Yilin Zhao, Haibo Tong, Kai Li, FeiFei Zhao, Yi Zeng
Large language models (LLMs) are increasingly embedded in AI for Science (AI4Science) workflows, from scientific question answering and literature analysis to laboratory planning and autonomous discovery. This progress creates an urgent need for safety benchmarks that evaluate not only scientific competence, but also whether models recognize and avoid risks in high-stakes scientific contexts.
arXiv:2606. 28332v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly used for medical and health-related questions, yet their safety in high-risk medical scenarios remains poorly understood.
By Yige Li, Jun Sun, Wei Zhao, Zhe Li, Yutao Wu, Hanxun Huang, Xiang Zheng, Xingjun Ma
arXiv:2609.01210v1 Announce Type: cross
Abstract: Safety benchmarks for large language models often assess the risk of a user query, although the outcome of question answering depends on whether the...
By Rui Yang, Shuang Huang, Junhua Liu, Ziqi Zhao, Qingzhong Yan, Yuhang Sun, Cong Liu, Guoping Hu, Rui Mei, Jing Shao
arXiv:2508. 00923v3 Announce Type: replace Abstract: Large language models (LLMs) are increasingly used to answer health-related questions and support healthcare workflows, yet evidence for their safety still relies heavily on static benchmarks that can rapidly become obsolete or be optimized against.
By Jiazhen Pan (Cherise), Bailiang Jian (Cherise), Paul Hager (Cherise), Yundi Zhang (Cherise), Che Liu (Cherise), Friederike Jungmann (Cherise), Hongwei Bran Li (Cherise), Julian Canisius (Cherise), Chenyu You (Cherise), Junde Wu (Cherise), Jiayuan Zhu (Cherise), Fenglin Liu (Cherise), Yuyuan Liu (Cherise), Niklas Bubeck (Cherise), Moritz Knolle (Cherise), Chen (Cherise), Chen (Cherise), Christian Wachinger, Zhenyu Gong, Cheng Ouyang, Georgios Kaissis, Benedikt Wiestler, Daniel Rueckert
Safety benchmarks for large language models often assess the risk of a user query, although the outcome of question answering depends on whether the response violates a policy. This distinction is cri...
arXiv:2601. 17642v2 Announce Type: replace Abstract: Safety alignment in Large Language Models is critical for healthcare; however, reliance on binary refusal boundaries often results in over-refusal of benign queries or unsafe compliance with harmful ones.
By Zhihao Zhang, Liting Huang, Guanghao Wu, Preslav Nakov, Heng Ji, Usman Naseem
arXiv:2606. 08234v1 Announce Type: new Abstract: LLM-based scientific agents have shown strong capacity for autonomous research, yet their safety layers remain structurally divorced from core reasoning: they inspect pipeline outputs rather than shaping the deliberation that produces them.
By Tanush Swaminathan, Runmin Jiang, Letian Zhang, Min Xu
The paper investigates whether existing AI safety benchmarks, designed for large language models, are suitable for evaluating small language models (SLMs). By testing five benchmark suites on 26 open‑source SLMs with a unified scoring rubric, the authors find that ambiguous judgments dominate, especially for complex prompts and certain architectures. This ambiguity, linked to factors like lexical density and output perplexity, undermines the reliability of aggregate leaderboards and reveals a confound between model capability and perceived safety.
By Nyamtulla Shaik, Fengjun Li, Bo Luo
arXiv:2607. 01153v3 Announce Type: replace-cross Abstract: Safety evaluations for language models increasingly depend on judgments about ambiguous natural-language behaviour: whether a model followed an instruction, refused appropriately, complied with a policy, or misreported progress in an agentic task.
By Brett Reynolds
arXiv:2606. 00160v1 Announce Type: cross Abstract: Large language models (LLMs) suffer from degraded safety capabilities even when fine-tuned with benign datasets.
By Junbo Zhang, Qianli Zhou, Xinyang Deng, Wen Jiang, Jie Pan, Jinbiao Zhu