arXiv Machine Learning

RegionFM: Interpretable Region-Based Brain MRI Classification Using Foundation Model Embeddings

arXiv:2607. 16325v1 Announce Type: cross Abstract: Foundation models provide powerful representations for brain MRI analysis, but their predictions remain difficult to interpret in anatomically meaningful terms.

arXiv AI
Jun 10

Tractogram foundation model

arXiv:2606. 09893v1 Announce Type: cross Abstract: Diffusion MRI (dMRI) tractography is the only noninvasive approach for mapping white-matter pathways in the living human brain.

By Guikun Chen, Yuqian Chen, Yijie Li, Yogesh Rathi, Nikos Makris, Fan Zhang, Wenguan Wang, Lauren J. O'Donnell
arXiv AI
Jun 12

BrainDINO: A Brain MRI Foundation Model for Generalizable Clinical Representation Learning

arXiv:2604. 27277v3 Announce Type: replace-cross Abstract: Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data.

By Yizhou Wu, Shansong Wang, Yuheng Li, Mojtaba Safari, Mingzhe Hu, Chih-Wei Chang, Harini Veeraraghavan, Xiaofeng Yang
arXiv AI
Jun 30

ReMAP-PET: Beyond Visual Understanding -- Learning Region-Guided Metabolic Alignment Semantics from Brain PET

arXiv:2606. 29577v1 Announce Type: cross Abstract: Positron Emission Tomography (PET) reveals brain metabolism and is clinically central to neurodegenerative disease assessment, yet existing 3D brain foundation models treat PET as generic volumetric data, missing the structured regional metabolic information that distinguishes it from structural neuroimaging.

By Dasen Dai, Yanteng Zhang, Shuoqi Li, Yuxiang Wei, Hongjie Yu, Qingxin Zhang, Qizhen Lan, Jagath C. Rajapakse, Vince D. Calhoun
Hugging Face Trending Papers
Jun 28

ReMAP-PET: Beyond Visual Understanding -- Learning Region-Guided Metabolic Alignment Semantics from Brain PET

Positron Emission Tomography (PET) reveals brain metabolism and is clinically central to neurodegenerative disease assessment, yet existing 3D brain foundation models treat PET as generic volumetric data, missing the structured regional metabolic information that distinguishes it from structural neuroimaging. To address these limitations, we propose ReMAP-PET, a framework that moves beyond visual encoding by supervising a partially-tuned MedicalNet 3D ResNet-50 with brain regional standardized uptake value ratio (SUVR) profiles through joint regression and contrastive objectives, enabling the encoder to learn the metabolic semantics underlying PET modality.

arXiv AI
Jul 17

Parameter-efficient Prompt Tuning of Vision Foundation Model With Adaptive Focal Loss for Interpretable MCI Screening

arXiv:2607. 15047v1 Announce Type: cross Abstract: Mild Cognitive Impairment is a critical early stage of cognitive decline that frequently precedes Alzheimer's disease, yet its automated detection from neuropsychological drawing tests remains fundamentally constrained by data scarcity, class imbalance, and diagnostic ambiguity near clinical boundaries.

By Javad Khoramdel, Farhad Hoseyni, Amirhossein Nikoofard
arXiv Machine Learning
Jun 5

Cross-scale spatially-aware generative modeling of transcriptomic programs underlying neurodegenerative brain organization

arXiv:2606. 05870v1 Announce Type: cross Abstract: Neurodegenerative disorders such as Alzheimer's disease exhibit highly organized patterns of regional brain vulnerability, yet the biological mechanisms underlying this spatial selectivity remain incompletely understood.

By Krishnakumar Vaithianathan (for the Alzheimer's Disease Neuroimaging Initiative)
arXiv AI
5d ago

Mr3D-VL: A generalist vision language foundation model for Multiparametric 3D Magnetic Resonance Imaging

arXiv:2608. 12689v1 Announce Type: cross Abstract: Multi-parametric magnetic resonance imaging (mpMRI) is a cornerstone for brain tumor diagnosis and treatment, yet current AI models face critical limitations: their lack of natural language interaction and interpretability impedes spatial information integration and cross-modal reasoning required clinically.

By Zhi Qiao, Xintong Wu, Yichu He, Feng Shi