arXiv:2601.10485v5 Announce Type: replace
Abstract: Domain-specific knowledge graphs (DKGs) are critical yet often suffer from limited coverage compared to General Knowledge Graphs (GKGs). Existing t...
By Runhao Zhao, Weixin Zeng, Wentao Zhang, Chong Chen, Zhengpin Li, Xiang Zhao, Lei Chen
arXiv:2609.06779v1 Announce Type: cross
Abstract: Drug repurposing aims to identify new therapeutic uses for existing compounds and, compared with de novo drug discovery, offers a faster and more cos...
By Zijie Liu, Hongxuan Li, Zhen Tan, Jinhao Duan, Baixiang Huang, Zunpeng Liu, Kai Shu, Tianlong Chen
arXiv:2606.22419v3 Announce Type: replace
Abstract: A recent Nature Medicine study reports that general-purpose frontier LLMs outperform specialized retrieval-augmented clinical tools on medical benc...
By Madhulatha Mandarapu, Sandeep Kunkunuru
Thalamus‑Reasoning is a 9B multimodal large language model that embeds bulk or single‑cell transcriptomes as continuous vectors, allowing them to be interleaved with natural‑language instructions and other samples. The model is trained on a large corpus that links experimental measurements to biological knowledge and task supervision, covering 157 task groups and 5.21 million conversations. It outperforms competing models on several held‑out annotation tasks, the GEO‑OmicsQA benchmark, and PerturbQA perturbation‑response prediction, demonstrating the benefit of continuous omics representations over text‑only gene lists.
By Maciej Sypetkowski, {\L}ukasz Smoli\'nski, Remigiusz Kinas, Joanna Krawczyk, Bart{\l}omiej Hofman, Aleksandra Mo\.zwi{\l}{\l}o, Micha{\l} Pikusa, Tomasz Jetka, Rafa{\l} Powalski
arXiv:2604. 06684v2 Announce Type: replace Abstract: Clinical reasoning over electronic health records (EHRs) is a fundamental yet challenging task in modern healthcare.
By Yue Fang, Weibin Liao, Yuxin Guo, Jiaran Gao, Hongxin Ding, Jinyang Zhang, Xinke Jiang, Zhibang Yang, Junfeng Zhao, Yasha Wang, Liantao Ma
arXiv:2607. 14149v1 Announce Type: new Abstract: Although large language models (LLMs) have set benchmarks for zero-shot reasoning, their deployment remains cost-prohibitive and environmentally taxing.
By Dimitrios Kelesis, Konstantinos Bougiatiotis, Georgios Paliouras