arXiv AI

Finding H. pylori in the Fine Print: Evidence-Linked Multi-Agent Case Finding from Gastric Biopsy Reports

arXiv:2607. 06435v1 Announce Type: new Abstract: Data from Singapore indicated that about 31% of the population had evidence of Helicobacter pylori infection.

arXiv AI
Sep 1

From Analytics to Tumor Boards: An Evidence-Linked Multi-Agent Workflow for Oncology Feature Extraction

arXiv:2608.28974v1 Announce Type: new Abstract: Clinically relevant oncology information is distributed across heterogeneous, longitudinal documentation, creating substantial abstraction burden and r...

By Daniel Kang, Michelle Hu, Soorya Ram Shimgekar, Shayan Vassef, Yufan Wang, Anit Kumar Sahu, Munmun De Choudhury, Vedant Das Swain, Christian Poellabauer, Li Yan Khor, Koustuv Saha, Robert Wojciechowski, Elliot Kidd, Piyum Zonooz, Navin Kumar
arXiv Computation and Language
Sep 7

VERGE: Verification-Enhanced Refinement for Grounded Extraction of Early-Onset Colorectal Cancer Symptoms in Clinical Notes

The paper introduces VERGE, a verification-enhanced refinement workflow that extracts six red‑flag symptoms and family‑history risk status for early‑onset colorectal cancer from free‑text clinical notes. VERGE uses retrieval‑augmented generation followed by a bounded verification‑refinement cycle that checks textual grounding and clinical validity, correcting claims until resolved or escalating to human review. In evaluation on 4,033 clinician‑labeled note‑finding pairs, VERGE improved precision from 0.764 to 0.849 and MCC from 0.681 to 0.730 compared to a single‑agent baseline, while requiring human review for only 1.5 % of claims.

By Nikkie Hooman, Monarch Nigam, Amy E. Hughes, Rasmi G. Nair, Mehak Gupta
arXiv AI
Oct 31

Advancing Clinical Genomic Analysis with a Skill-Centred Agent

The paper introduces ClinGeX, a large‑language‑model agent that uses 105 curated executable skills to automate clinical genomic analysis. In benchmark tests, ClinGeX achieved 71.7% macro‑averaged task‑level concordance, outperforming the best comparator at 45.7%. Human‑AI collaboration studies showed ClinGeX significantly improved case‑level concordance across variant analysis, rare disease interpretation, and oncology decision‑making, while also reducing interpretation time.

By Qiaoyu Zheng, Weike Zhao, Yanjie Fan, Ye Cao, Mengqi Jiang, Xiao Zhou, Xiaoman Zhang, Pengcheng Qiu, Yongguo Yu, Yanfeng Wang, Ya Zhang, Chaoyi Wu, Weidi Xie
arXiv AI
Jun 16

MedCollab: IBIS-Guided Multi-Agent Collaboration with Hierarchical Disease Relation Chains for Clinical Diagnosis

arXiv:2603. 01131v3 Announce Type: replace-cross Abstract: Clinical diagnosis is a gradual process of evidence integration, in which physicians move from symptoms and medical history to examinations, competing hypotheses, disease relations, and treatment decisions.

By Yuqi Zhan, Xinyue Wu, Tianyu Lin, Yutong Bao, Xiaoyu Wang, Weihao Cheng, Huangwei Chen, Feiwei Qin, Zhu Zhu
arXiv AI
Aug 26

LUCAID: Agentic Multimodal AI for Lung Cancer Precision Pathology

LUCAID is an agentic multimodal AI system designed for precision lung cancer pathology, integrating nine modules that cover the entire routine workflow—from quality control and tumor detection to histological subtyping, microenvironment profiling, cellularity quantification, and biomarker scoring (PD‑L1, MET, TROP‑2). The system generates automated structured reports and allows interactive querying of module outputs. In prospective clinical validation, LUCAID achieved 93.0% concordance with an expert‑panel reference standard for clinically actionable decisions, outperforming five experienced thoracic pathologists who ranged from 68.3% to 81.1% concordance.

By Marie-Lisa Eich, Kai Standvoss, Timo Milbich, Alexander M\"ollers, Miriam H\"agele, Philipp Anders, Lars Tharun, Hanna Kontradiuk, Sebastian Kons, Nader Aldoj, Recepcan Adig\"uzel, Adam Narai, Lukas H\"onig, Jonathan Striebel, Binru Yang, Mihnea P. Dragomir, Marvin Sextro, Philipp Keyl, Philipp Jurmeister, Rosemarie Krupar, Evelyn Ramberger, James Wells, Julika Ribbat-Idel, Andreas Kunft, Hussam Shuaib, Christian Groh\'e, Reinhard B\"uttner, David Horst, Klaus-Robert M\"uller, Lukas Ruff, Maximilian Alber, Frederick Klauschen, Simon Schallenberg
arXiv AI
Oct 16

ReviewPilot: A Multi-Agent System for Screening and Data Extraction in Systematic Reviews

ReviewPilot is a conversational multi‑agent system designed to automate the PRISMA workflow for systematic literature reviews, covering both paper screening and evidence extraction. Researchers can customize screening criteria and extraction schemas through dialogue, with a project memory preserving configurations and revisions. The system records the rationale for each screening decision and the source of every extracted value, and it has demonstrated superior performance to single‑prompt LLMs and AgentSLR in epidemiology, achieving screening macro F1 scores up to 0.776 and extraction F1 up to 0.788, while also showing close agreement with human annotators in biomedicine and human‑computer interaction case studies.

By Zhaoqian Xue, Shaoze Zhou, Xuexin Li, Junting Mu, Haozheng Liu, Zhongyin Wang, Yichun He, Renkai Ma, Hao Zhou, Sarah Bratt, Siyuan Ma, Chen Chen, Lingyao Li
arXiv Computation and Language
Aug 27

Retrieval-Augmented Agentic Rubric Generation for Reliable Medical Response Evaluation

The paper introduces a retrieval‑augmented multi‑agent framework that automatically generates instance‑specific evaluation rubrics for medical language models. By retrieving authoritative medical evidence, decomposing it into atomic facts, and combining these with user interaction constraints, the system produces fine‑grained criteria that outperform GPT‑4o on HealthBench and LLMEval‑Med. The generated rubrics also guide response refinement, improving medical LLM output quality by 9.2%.

By Yinzhu Chen, Abdine Maiga, Hossein A. Rahmani, Emine Yilmaz