arXiv Computer Vision

Longitudinal Retinal Vascular Remodeling in Myopic Children Treated with Orthokeratology or Defocus Lenses: A Two-Year Comparative Study

arXiv AI
Jun 16

EyeMVP: OCT-Informed Fundus Representation Learning via Paired CFP--OCT Pretraining

arXiv:2606. 15129v1 Announce Type: cross Abstract: Color fundus photography (CFP) is the mainstay for large-scale retinal screening, yet its diagnostic capacity is constrained by the lack of depth-resolved structural information.

By Zhuo Deng, Ruiheng Zhang, Ziheng Zhang, Weihao Gao, Yitong Li, Qian Wang, Lei Shao, Jiaoyue Dong, Zhixi Zeng, Lijian Fang, Haibo Wang, Xiaobin Lin, Tao Liu, Zhicheng Du, Zhengwei Zhang, Lin Yang, Zheng Gong, Xinyu Zhao, Zhenquan Wu, Fang Li, Zhiguang Zhou, Guoming Zhang, Sun Jing, Han Lv, Wenbin We, Lan Ma
arXiv Computer Vision
Sep 1

retinalysis-vascx: An explainable software toolbox for the extraction of retinal vascular biomarkers

arXiv:2602.08580v4 Announce Type: replace-cross Abstract: Automatic extraction of retinal vascular biomarkers from color fundus images (CFI) is crucial for large-scale studies of the retinal vasculat...

By Jose D. Vargas Quiros, Michael J. Beyeler, Sofia Ortin Vela, EyeNED Reading Center, Sven Bergmann, Caroline C. W. Klaver, Bart Liefers, VascX Research Consortium
arXiv Computation and Language
Sep 7

Retinal OCTA Phenotyping with LLM Reporting for Alzheimer's Disease

The study introduces an explainable OCTA pipeline for Alzheimer’s disease phenotyping that combines vessel segmentation, layer‑specific biomarker extraction, and label‑free phenotyping with large language model (LLM) reporting. Using 117 images from 39 subjects, the segmentation models achieved high ROC‑AUC (0.916–0.970) and Dice scores (0.695–0.781), and six vascular biomarkers were used to create subject‑level profiles for exploratory clustering. LLMs (GPT, Gemini, Llama) produced measurement‑grounded reports evaluated for citation faithfulness and diagnostic caution, offering a transparent, non‑diagnostic link between retinal vascular data and Alzheimer’s research.

By Progga Paromita Dutta, Jeba Maliha, Md Rafiul Kabir
arXiv Computer Vision
Aug 28

Automated 2D and 3D Segmentation of AMD and DME Lesions in OCT

This study presents four deep‑learning pipelines—two‑dimensional and three‑dimensional—for segmenting age‑related macular degeneration (AMD) and diabetic macular edema (DME) lesions in optical coherence tomography (OCT) images. The models achieve Dice scores between 0.76 and 0.82 and demonstrate strong volumetric and surface calibration (r_vol, r_surf ≥ 0.97) on an in‑domain validation set. Generalization was assessed on the OLIVES clinical cohort using proxy metrics such as biomarker AUROC, central subfield thickness correlation, and longitudinal concordance, showing that the predictions still track clinical biomarkers outside the training distribution, albeit with reduced strength.

By Lucia Sundberg, Zhihao Zhao, M. Ali Nasseri
arXiv Computer Vision
Sep 14

An Ultra-Widefield Swept-Source OCTA Dataset and a Polar-Gated Mamba Network for Retinal Vessel Segmentation

arXiv:2609.12574v1 Announce Type: new Abstract: Ultra-widefield (UWF) swept-source optical coherence tomography angiography (SS-OCTA) enables large-area retinal vascular imaging, yet vessel segmentat...

By Yang Liu, Yibing Shen, Keming Zhao, Cenk Jiang, Zhenghang Qian, Zhicheng Du, Chen Xiong, Qidong Shao, Zijun Lin, Yunqi Hu, Jingjing Zhou, Lian Zhang, Peter E. Lobie, Peiwu Qin, Chengming Yang
arXiv Computer Vision
Sep 23

Interpretable AI plus Handheld, Portable Retinal Photographs: A Low-Cost Glaucoma Screening Solution for West Africa

The study presents an interpretable AI framework for glaucoma screening using low-cost handheld retinal cameras in a West African population. Trained on 681 participants, the system achieved high performance across vessel segmentation, cup/disc segmentation, and optic nerve head feature detection, with classification AUCs of 0.85 for the handheld device and 0.93 for a tabletop camera. The model provides confidence scores and visual explanations to aid clinical interpretation.

By Charis Y. N. Chiang, Tarela Sarimiye, Adeyinka Ashaye, Martin Buist, Michael A. Hauser, Olusola Olawoye, Micha\"el J. A. Girard
arXiv Computer Vision
Sep 4

ARCOS: Zero-shot Boundary Localization for Corneal Layer Segmentation Across Optical Coherence Tomography Devices

ARCOS is a patch-based zero-shot boundary localization framework designed for corneal layer segmentation in optical coherence tomography (OCT) images. It predicts boundary heatmaps from overlapping native-resolution patches, stitches these predictions across full B-scans, and refines them with a self-conditioned module to produce continuous, anatomically ordered layer segmentations. Evaluated on clinical OCT data from multiple devices, ARCOS achieved 95.1% off‑by‑one boundary accuracy on matched-device tests and 84.3% on unseen devices, with low mean absolute boundary errors and accurate thickness estimates.

By Nuno Vivas Br\'as, Benjamin Memmi, Ma\"elle Bouhassane, Cristina Georgeon, Vincent Borderie, Karsten Plamann, Anatole Chessel